The design and implementation of a Generalized Predictive Control(GPC)strategy for the superheated steam temperature regulation in a supercritical(SC)coal-fired power plant is presented.A Controlled Auto-Regressive Mo...The design and implementation of a Generalized Predictive Control(GPC)strategy for the superheated steam temperature regulation in a supercritical(SC)coal-fired power plant is presented.A Controlled Auto-Regressive MovingAverage(CARMA)model of the plant is derived from using the experimental data to approximately predict the plant’s future behavior.This model is required by the GPC algorithm to calculate the future control inputs.A new GPC controller is designed and its performance is tested through extensive simulation studies.Compared with the performance of the plant using a conventional PID controller,the steam temperature controlled by the GPC controller is found to be more stable.The stable steam temperature leads to more efficient plant operation and energy saving,as demonstrated by the simulation results.Plant performance improvement is also tested while the plant experiences the load demand changes and disturbances resulting from the malfunctioning of coal mills.展开更多
Human BCL10 (hBCL10) protein is a signal transduction molecule originally identified because of its direct involvement in a subset of mucosa-associated lymphoid tissue (MALT) lymphomas, and later recognized as a cruci...Human BCL10 (hBCL10) protein is a signal transduction molecule originally identified because of its direct involvement in a subset of mucosa-associated lymphoid tissue (MALT) lymphomas, and later recognized as a crucial factor in regulating activation of NF-kB transcription factor following antigen receptor stimulation on lymphocytes. In this study, we characterized the NF-kB inducing activity of porcine BCL10 (pBCL10). pBCL10 oligimerizes, binds to components of the CARMA/ BCL10/MALT1 complex and forms cytoplasmic filaments. Functionally, in human cells pBCL10 is more effective in activating NF-kB compared to hBCL10, possibly due to the lack of carboxy-terminal inhibitory serine residues present in the human protein. Also, depletion experiments carried out through expression of short hairpin RNAs targeting hBCL10 indicate that pBcl10 can functionally replace the human protein and retains its higher NF-kB-inducing property in the absence of hBCL10. Our results contribute useful information on BCL10 protein in pigs, and may help the development of strategies based on the control of the immune response in pigs.展开更多
Carma HintonGardon own a small Richard Gardonand her husband Richard film studio named Long Bow. Richard Gardon is the studio's boss and cameraman and employs several Harvard students as part-timers. Xiao Lan, a S...Carma HintonGardon own a small Richard Gardonand her husband Richard film studio named Long Bow. Richard Gardon is the studio's boss and cameraman and employs several Harvard students as part-timers. Xiao Lan, a Shanghai girl oraduating from Harvard's East Asia展开更多
基金supported by the EPSRC Grant(EP/G062889/2),Advantage West Midlands and the European Regional Development Agency(Birmingham Science City Energy Efficiency&Demand Reduction project).
文摘The design and implementation of a Generalized Predictive Control(GPC)strategy for the superheated steam temperature regulation in a supercritical(SC)coal-fired power plant is presented.A Controlled Auto-Regressive MovingAverage(CARMA)model of the plant is derived from using the experimental data to approximately predict the plant’s future behavior.This model is required by the GPC algorithm to calculate the future control inputs.A new GPC controller is designed and its performance is tested through extensive simulation studies.Compared with the performance of the plant using a conventional PID controller,the steam temperature controlled by the GPC controller is found to be more stable.The stable steam temperature leads to more efficient plant operation and energy saving,as demonstrated by the simulation results.Plant performance improvement is also tested while the plant experiences the load demand changes and disturbances resulting from the malfunctioning of coal mills.
文摘Human BCL10 (hBCL10) protein is a signal transduction molecule originally identified because of its direct involvement in a subset of mucosa-associated lymphoid tissue (MALT) lymphomas, and later recognized as a crucial factor in regulating activation of NF-kB transcription factor following antigen receptor stimulation on lymphocytes. In this study, we characterized the NF-kB inducing activity of porcine BCL10 (pBCL10). pBCL10 oligimerizes, binds to components of the CARMA/ BCL10/MALT1 complex and forms cytoplasmic filaments. Functionally, in human cells pBCL10 is more effective in activating NF-kB compared to hBCL10, possibly due to the lack of carboxy-terminal inhibitory serine residues present in the human protein. Also, depletion experiments carried out through expression of short hairpin RNAs targeting hBCL10 indicate that pBcl10 can functionally replace the human protein and retains its higher NF-kB-inducing property in the absence of hBCL10. Our results contribute useful information on BCL10 protein in pigs, and may help the development of strategies based on the control of the immune response in pigs.
文摘Carma HintonGardon own a small Richard Gardonand her husband Richard film studio named Long Bow. Richard Gardon is the studio's boss and cameraman and employs several Harvard students as part-timers. Xiao Lan, a Shanghai girl oraduating from Harvard's East Asia
