Background:Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options.Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate an...Background:Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options.Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen.The dermal matrix serves as a scaffold for fibroblasts and endothelial cells.Vascularization of the matrix begins after 2-3 weeks,and eventually,the matrix incorporates with the tissue to create a new dermis.The main advantage of the Integra is that the neodermis is of the same quality as a native dermis.Case presentation:In this case report,we present post-burn breast reconstruction of a 12-year-old girl using Integra,with a long follow-up of 7 years.To the best of our knowledge,there is no published follow-up of breast development after reconstruction with Integra from its beginning point at the age of puberty until after the growing process has terminated.Conclusions:Integra is a reliable reconstructive tool for burned breast.If done before puberty,it can help in getting normal developing tissue with satisfying esthetic results of size,shape and symmetry.展开更多
文摘Background:Full thickness burns of the chest in childhood are a devastating problem that requires challenging reconstructive options.Integra is a bilaminate artificial dermis composed of shark chondroitin 6-sulfate and bovine collagen.The dermal matrix serves as a scaffold for fibroblasts and endothelial cells.Vascularization of the matrix begins after 2-3 weeks,and eventually,the matrix incorporates with the tissue to create a new dermis.The main advantage of the Integra is that the neodermis is of the same quality as a native dermis.Case presentation:In this case report,we present post-burn breast reconstruction of a 12-year-old girl using Integra,with a long follow-up of 7 years.To the best of our knowledge,there is no published follow-up of breast development after reconstruction with Integra from its beginning point at the age of puberty until after the growing process has terminated.Conclusions:Integra is a reliable reconstructive tool for burned breast.If done before puberty,it can help in getting normal developing tissue with satisfying esthetic results of size,shape and symmetry.