This paper aims to propose the sequential pattern discovery method of Deoxyribonucleic Acid (DNA) sequence database in order to identify cancer disease. The DNA which is composed of amino acids of gene P53 is mutated....This paper aims to propose the sequential pattern discovery method of Deoxyribonucleic Acid (DNA) sequence database in order to identify cancer disease. The DNA which is composed of amino acids of gene P53 is mutated. It effects to change of P53 formation. Sequential pattern discovery is a process of extracting data to generate knowledge about the series of events that has the sequences in a certain frequency so that it creates a pattern. PrefixSpan is to propose method to find a pattern of DNA sequence database. As a result, there are various selected patterns of DNA sequence. The pattem which has high similarity is used as biomarker to identify the breast cancer disease. The performance measure of support value average is 0.8. It means that the frequent sequence pattern is high. Another measure is confidence. All of the confidence values are 1. Then, the last performance measure is lift ratio at average more than 1. It means that the composed sequence items in the pattern has high dependency and relatedness. Futhermore, the selected patterns are applied as biomarker with accuracy as 100%.展开更多
Aim: Many classifications have been described in the literature for ptotic breasts, focusing on the nipple areola complex position compared to the inframammary fold. These use centimeters and lateral views to illustra...Aim: Many classifications have been described in the literature for ptotic breasts, focusing on the nipple areola complex position compared to the inframammary fold. These use centimeters and lateral views to illustrate their various grades in a manner always insufficient to propose a clear treatment plan aimed at achieving natural results. We discuss a new dynamic approach to breast ptosis with a complete treatment algorithm. Methods: Patients were examined in a standing position first with hands down then with hands up. We observed the elevation of the inter-nipple line called the 'BK-line' and its relationship to a sternal benchmark that we call the 'BK-Point'. The 'hands-up test' was positive when the line crossed the landmark. The algorithm defines the indication according to this clinical examination and to the patient's wishes. An angle between the nipple, the 'BK-point' and the body meridian (called the 'BK angle') was appreciated before and after surgery. This angle should become 90° or more after ptosis treatment. Results: Three hundred patients were treated for ptotic breasts, including breast reductions, from January 2010 to September 2017. The definitions of 'normal' non-ptotic and ptotic breast and the 'ideal' breast were reconsidered. The surgical indications were adjusted to the clinical situation and to the patient's wishes, refining the final version of the algorithm. Conclusion: This new classification is easy, reproducible and efficient. We propose an appropriate algorithm to treat every situation that takes care to consider patient's wishes and expectations.展开更多
Aim:The primary author previously described his technique for periareolar closure in mastopexy using a pinwheel interlocking purse string with absorbable barbed suture and now reports the results of a retrospective ph...Aim:The primary author previously described his technique for periareolar closure in mastopexy using a pinwheel interlocking purse string with absorbable barbed suture and now reports the results of a retrospective photometric analysis comparing this technique with the same closure using Gortex®suture.This study is designed to compare the degree of areolar widening and safety profile of using absorbable barbed sutures for periareolar closure versus permanent smooth suture.Methods:A retrospective chart review was conducted of all patients whose periareolar closures were performed using an interlocking purse-string technique over a 10-year period.Only patients undergoing circumvertical mastopexy were included.All had photometric evaluation and follow-up performed within 6-24 months.Results:In total,20 patients(40 areolas),which were closed with absorbable barbed suture,were analyzed photometrically.In this suture group,areola size increased a mean of 4.9%from baseline,and no complications(0%)were observed.This compared favorably with previously reported complication rates using permanent sutures and with a series of cases presented herein in which permanent smooth suture was used for purse string closure.The degree to which absorbable barbed suture controls areolar spread was shown to be significantly better than those where permanent smooth purse string techniques were employed.Conclusion:Circumvertical mastopexy closures using absorbable barbed suture was shown to be safe and effective and compared favorably to older techniques using permanent smooth suture for similar closures.This paper lends support to the safety of using absorbable barbed suture in circumareolar closures to limit areolar spread.展开更多
文摘This paper aims to propose the sequential pattern discovery method of Deoxyribonucleic Acid (DNA) sequence database in order to identify cancer disease. The DNA which is composed of amino acids of gene P53 is mutated. It effects to change of P53 formation. Sequential pattern discovery is a process of extracting data to generate knowledge about the series of events that has the sequences in a certain frequency so that it creates a pattern. PrefixSpan is to propose method to find a pattern of DNA sequence database. As a result, there are various selected patterns of DNA sequence. The pattem which has high similarity is used as biomarker to identify the breast cancer disease. The performance measure of support value average is 0.8. It means that the frequent sequence pattern is high. Another measure is confidence. All of the confidence values are 1. Then, the last performance measure is lift ratio at average more than 1. It means that the composed sequence items in the pattern has high dependency and relatedness. Futhermore, the selected patterns are applied as biomarker with accuracy as 100%.
文摘Aim: Many classifications have been described in the literature for ptotic breasts, focusing on the nipple areola complex position compared to the inframammary fold. These use centimeters and lateral views to illustrate their various grades in a manner always insufficient to propose a clear treatment plan aimed at achieving natural results. We discuss a new dynamic approach to breast ptosis with a complete treatment algorithm. Methods: Patients were examined in a standing position first with hands down then with hands up. We observed the elevation of the inter-nipple line called the 'BK-line' and its relationship to a sternal benchmark that we call the 'BK-Point'. The 'hands-up test' was positive when the line crossed the landmark. The algorithm defines the indication according to this clinical examination and to the patient's wishes. An angle between the nipple, the 'BK-point' and the body meridian (called the 'BK angle') was appreciated before and after surgery. This angle should become 90° or more after ptosis treatment. Results: Three hundred patients were treated for ptotic breasts, including breast reductions, from January 2010 to September 2017. The definitions of 'normal' non-ptotic and ptotic breast and the 'ideal' breast were reconsidered. The surgical indications were adjusted to the clinical situation and to the patient's wishes, refining the final version of the algorithm. Conclusion: This new classification is easy, reproducible and efficient. We propose an appropriate algorithm to treat every situation that takes care to consider patient's wishes and expectations.
文摘Aim:The primary author previously described his technique for periareolar closure in mastopexy using a pinwheel interlocking purse string with absorbable barbed suture and now reports the results of a retrospective photometric analysis comparing this technique with the same closure using Gortex®suture.This study is designed to compare the degree of areolar widening and safety profile of using absorbable barbed sutures for periareolar closure versus permanent smooth suture.Methods:A retrospective chart review was conducted of all patients whose periareolar closures were performed using an interlocking purse-string technique over a 10-year period.Only patients undergoing circumvertical mastopexy were included.All had photometric evaluation and follow-up performed within 6-24 months.Results:In total,20 patients(40 areolas),which were closed with absorbable barbed suture,were analyzed photometrically.In this suture group,areola size increased a mean of 4.9%from baseline,and no complications(0%)were observed.This compared favorably with previously reported complication rates using permanent sutures and with a series of cases presented herein in which permanent smooth suture was used for purse string closure.The degree to which absorbable barbed suture controls areolar spread was shown to be significantly better than those where permanent smooth purse string techniques were employed.Conclusion:Circumvertical mastopexy closures using absorbable barbed suture was shown to be safe and effective and compared favorably to older techniques using permanent smooth suture for similar closures.This paper lends support to the safety of using absorbable barbed suture in circumareolar closures to limit areolar spread.
