Emerging viruses are viruses whose occurrence has risen within the past twenty years,or whose presence is likely to increase in the near future.Diseases caused by emerging viruses are a major threat to global public h...Emerging viruses are viruses whose occurrence has risen within the past twenty years,or whose presence is likely to increase in the near future.Diseases caused by emerging viruses are a major threat to global public health.In spite of greater awareness of safety and containment procedures,the handling of pathogenic viruses remains a likely source of infection,and mortality,among laboratory workers.There is a steady increase in both the number of laboratories and scientist handling emerging viruses for diagnostics and research.The potential for harm associated to work with these infectious agents can be minimized through the application of sound biosafety concepts and practices.The main factors to the prevention of laboratory-acquired infection are well-trained personnel who are knowledgable and biohazard aware,who are perceptive of the various ways of transmission,and who are professional in safe laboratory practice management.In addition,we should emphasize that appropriate facilities,practices and procedures are to be used by the laboratory workers for the handling of emerging viruses in a safe and secure manner.This review is aimed at providing researchers and laboratory personnel with basic biosafety principles to protect themselves from exposure to emerging viruses while working in the laboratory.This paper focuses on what emerging viruses are,why emerging viruses can cause laboratory-acquired infection,how to assess the risk of working with emerging viruses,and how laboratory-acquired infection can be prevented.Control measures used in the laboratory designed as such that they protect workers from emerging viruses and safeguard the public through the safe disposal of infectious wastes are also addressed.展开更多
Introduction:In today’s globalized world where travel is commonplace,a threat in one region can easily spread throughout the whole world.It is,therefore,essential for multi-disciplinary risk assessment,risk mitigatio...Introduction:In today’s globalized world where travel is commonplace,a threat in one region can easily spread throughout the whole world.It is,therefore,essential for multi-disciplinary risk assessment,risk mitigation,and collaborative strategies to take place among various stakeholders to mitigate this.Any strategic plan to deal with biosecurity,therefore,needs to be a complete loop,top to bottom and bottom to top.This paper describes the results of Project 62,which involved mapping and biosecurity risk assessment in South East Asia.Materials and methods:The mapping and biosecurity risk assessment activities for the participating partner countries was carried out in two phases.The first phase involved risk assessment by six partnercountry bio-experts for their own countries and the second phase involved conducting a joint Strengths,Weaknesses,Opportunities,and Threats(SWOT)analysis and risk assessment for the South East Asian region as whole,together with international bio-experts at a workshop.Results and discussion:The following key recommendations of the project show that biosecurity needs to be addressed through stakeholder engagement at multiple levels starting from the top echelons of the government to the worker who needs to recognize and understand the threats they might face:1.Systematic analysis of existing information from BWC ISU Article 10,IHR capacities,JEE,UN Security Council Resolution 1540 Action Plan,EU CBRN NAP,and other relevant sources to develop a common understanding of the definition of biosecurity for all stakeholders in the region.2.Creation of programs for awareness building in biosecurity,not limiting them to laboratory biosecurity but using an all-inclusive approach to include border biosecurity,pandemic response,etc.3.Creation of a country-specific list of high-risk biological materials.4.Compulsory standardized biosecurity training,including responsible conduct in biosecurity research.5.Framework for one-health and security interface addressing biosecurity threats.6.Framework for展开更多
Availability of mobile laboratories can facilitate rapid on-spot detection of pathogens,monitor its presence in certain populations and inform health authorities to take immediate remedial measures.Currently available...Availability of mobile laboratories can facilitate rapid on-spot detection of pathogens,monitor its presence in certain populations and inform health authorities to take immediate remedial measures.Currently available biosafety and biosecurity guidelines and policies may not completely articulate the increased demand to manage mobile units in infectious disease outbreaks in remote parts of the country for rapid diagnosis,and also allows research and epidemiological study take place appropriately.The main objective of this study is to evaluate the current limitations and develop and implement biosafety and biosecurity guidelines as well as the protocols for operations,security,and response plan of mobile biosafety level 2 laboratories and their deployment.Keeping in view the sensitivity of it,a comprehensive plan was developed to address it in view of Global Health Security framework.Biosafety and biosecurity protocols were developed including Risk Assessment Tool(RAT)fitting the needs and strengthen the diagnostic and epidemiological capacity in the field covering remote parts of country to fill the gaps observed during the COVID-19 pandemic.Currently the biosafety and biosecurity best practices guidelines and biosecurity policy and regulations are directed mostly towards static laboratories.A biosafety and biosecurity manual developed to adopt and meet the requirements for MBSL 2.For acute health infectious threats including the COVID-19 outbreak and other epidemics,rapid diagnosis can curb and mitigate the problem before it gets out of its boundaries creating significant health risks for the public and economy.The deployment of mobile laboratories will certainly help in curbing these catastrophes.展开更多
文摘Emerging viruses are viruses whose occurrence has risen within the past twenty years,or whose presence is likely to increase in the near future.Diseases caused by emerging viruses are a major threat to global public health.In spite of greater awareness of safety and containment procedures,the handling of pathogenic viruses remains a likely source of infection,and mortality,among laboratory workers.There is a steady increase in both the number of laboratories and scientist handling emerging viruses for diagnostics and research.The potential for harm associated to work with these infectious agents can be minimized through the application of sound biosafety concepts and practices.The main factors to the prevention of laboratory-acquired infection are well-trained personnel who are knowledgable and biohazard aware,who are perceptive of the various ways of transmission,and who are professional in safe laboratory practice management.In addition,we should emphasize that appropriate facilities,practices and procedures are to be used by the laboratory workers for the handling of emerging viruses in a safe and secure manner.This review is aimed at providing researchers and laboratory personnel with basic biosafety principles to protect themselves from exposure to emerging viruses while working in the laboratory.This paper focuses on what emerging viruses are,why emerging viruses can cause laboratory-acquired infection,how to assess the risk of working with emerging viruses,and how laboratory-acquired infection can be prevented.Control measures used in the laboratory designed as such that they protect workers from emerging viruses and safeguard the public through the safe disposal of infectious wastes are also addressed.
文摘Introduction:In today’s globalized world where travel is commonplace,a threat in one region can easily spread throughout the whole world.It is,therefore,essential for multi-disciplinary risk assessment,risk mitigation,and collaborative strategies to take place among various stakeholders to mitigate this.Any strategic plan to deal with biosecurity,therefore,needs to be a complete loop,top to bottom and bottom to top.This paper describes the results of Project 62,which involved mapping and biosecurity risk assessment in South East Asia.Materials and methods:The mapping and biosecurity risk assessment activities for the participating partner countries was carried out in two phases.The first phase involved risk assessment by six partnercountry bio-experts for their own countries and the second phase involved conducting a joint Strengths,Weaknesses,Opportunities,and Threats(SWOT)analysis and risk assessment for the South East Asian region as whole,together with international bio-experts at a workshop.Results and discussion:The following key recommendations of the project show that biosecurity needs to be addressed through stakeholder engagement at multiple levels starting from the top echelons of the government to the worker who needs to recognize and understand the threats they might face:1.Systematic analysis of existing information from BWC ISU Article 10,IHR capacities,JEE,UN Security Council Resolution 1540 Action Plan,EU CBRN NAP,and other relevant sources to develop a common understanding of the definition of biosecurity for all stakeholders in the region.2.Creation of programs for awareness building in biosecurity,not limiting them to laboratory biosecurity but using an all-inclusive approach to include border biosecurity,pandemic response,etc.3.Creation of a country-specific list of high-risk biological materials.4.Compulsory standardized biosecurity training,including responsible conduct in biosecurity research.5.Framework for one-health and security interface addressing biosecurity threats.6.Framework for
文摘Availability of mobile laboratories can facilitate rapid on-spot detection of pathogens,monitor its presence in certain populations and inform health authorities to take immediate remedial measures.Currently available biosafety and biosecurity guidelines and policies may not completely articulate the increased demand to manage mobile units in infectious disease outbreaks in remote parts of the country for rapid diagnosis,and also allows research and epidemiological study take place appropriately.The main objective of this study is to evaluate the current limitations and develop and implement biosafety and biosecurity guidelines as well as the protocols for operations,security,and response plan of mobile biosafety level 2 laboratories and their deployment.Keeping in view the sensitivity of it,a comprehensive plan was developed to address it in view of Global Health Security framework.Biosafety and biosecurity protocols were developed including Risk Assessment Tool(RAT)fitting the needs and strengthen the diagnostic and epidemiological capacity in the field covering remote parts of country to fill the gaps observed during the COVID-19 pandemic.Currently the biosafety and biosecurity best practices guidelines and biosecurity policy and regulations are directed mostly towards static laboratories.A biosafety and biosecurity manual developed to adopt and meet the requirements for MBSL 2.For acute health infectious threats including the COVID-19 outbreak and other epidemics,rapid diagnosis can curb and mitigate the problem before it gets out of its boundaries creating significant health risks for the public and economy.The deployment of mobile laboratories will certainly help in curbing these catastrophes.
