Since the nanogenerator(NG) was invented in 2006, it has been successfully developed and utilized to harvest various forms of mechanical energy in vivo. The NGs promote the progress of self-powered biomedical devices....Since the nanogenerator(NG) was invented in 2006, it has been successfully developed and utilized to harvest various forms of mechanical energy in vivo. The NGs promote the progress of self-powered biomedical devices. Moreover, NGs can also be used as sensors to detect a variety of important physiological signals, which brings us closer to real-time, high-fidelity monitoring of physical and pathological information. This paper summarizes the in vivo applications of NGs as biomedical sensors, including in cardiac sensors, respiration sensors, blood pressure sensors, gastrointestinal sensors and bladder sensors.However, there are still many challenges in using NGs as sensors in vivo. For example, how can we minimize and encapsulate the NGs, how can we increase the stability and reliability during long-term detection, and how can we establish a corresponding relationship between the NG’s electrical output and the physiological signals. It is also critical to follow the medical principles more closely in the development of self-powered sensors in the future. We believe that the self-powered sensors would promote the development of the next-generation healthcare monitoring systems.展开更多
Intracavity absorption spectroscopy is a strikingly sensitive technique that has been integrated with a two-wavelength setup to develop a sensor for human breath.Various factors are considered in such a scenario,out o...Intracavity absorption spectroscopy is a strikingly sensitive technique that has been integrated with a two-wavelength setup to develop a sensor for human breath.Various factors are considered in such a scenario,out of which Relative Intensity Noise(RIN)has been exploited as an important parameter to characterize and calibrate the said setup.During the performance of an electrical based assessment arrangement which has been developed in the laboratory as an alternative to the expensive Agilent setup,the optical amplifier plays a pivotal role in its development and operation,along with other components and their significance.Therefore,the investigation and technical analysis of the amplifier in the system has been explored in detail.The algorithm developed for the automatic measurements of the system has been effectively deployed in terms of the laser’s performance.With this in perspective,a frequency dependent calibration has been pursued in depth with this scheme which enhances the sensor’s efficiency in terms of its sensitivity.In this way,our investigation helps us in a better understanding and implementation perspective of the proposed system,as the outcomes of our analysis adds to the precision and accuracy of the entire system.展开更多
基金supported by the National Key Research and Development Program of China (2016YFA0202703)the Scientific Research Foundation for Advanced Scholars of Foshan University (Gg07136, Gg07164)+4 种基金the Key Platform and Scientific Research Project of Guangdong Provincial Education Department (2018KTSCX246)the Science and Technology Planning Project of Guangdong Province (2018B030331001)the National Natural Science Foundation of China (61875015, 31571006, 81570202, and 8157037)the Beijing Natural Science Foundation (2182091)the National Youth Talent Support Program
文摘Since the nanogenerator(NG) was invented in 2006, it has been successfully developed and utilized to harvest various forms of mechanical energy in vivo. The NGs promote the progress of self-powered biomedical devices. Moreover, NGs can also be used as sensors to detect a variety of important physiological signals, which brings us closer to real-time, high-fidelity monitoring of physical and pathological information. This paper summarizes the in vivo applications of NGs as biomedical sensors, including in cardiac sensors, respiration sensors, blood pressure sensors, gastrointestinal sensors and bladder sensors.However, there are still many challenges in using NGs as sensors in vivo. For example, how can we minimize and encapsulate the NGs, how can we increase the stability and reliability during long-term detection, and how can we establish a corresponding relationship between the NG’s electrical output and the physiological signals. It is also critical to follow the medical principles more closely in the development of self-powered sensors in the future. We believe that the self-powered sensors would promote the development of the next-generation healthcare monitoring systems.
基金This work was supported in part by the German Academic Exchange Service(Deutsche Akademische Austausch Dienst(DAAD)),and in part by the University of Kassel.
文摘Intracavity absorption spectroscopy is a strikingly sensitive technique that has been integrated with a two-wavelength setup to develop a sensor for human breath.Various factors are considered in such a scenario,out of which Relative Intensity Noise(RIN)has been exploited as an important parameter to characterize and calibrate the said setup.During the performance of an electrical based assessment arrangement which has been developed in the laboratory as an alternative to the expensive Agilent setup,the optical amplifier plays a pivotal role in its development and operation,along with other components and their significance.Therefore,the investigation and technical analysis of the amplifier in the system has been explored in detail.The algorithm developed for the automatic measurements of the system has been effectively deployed in terms of the laser’s performance.With this in perspective,a frequency dependent calibration has been pursued in depth with this scheme which enhances the sensor’s efficiency in terms of its sensitivity.In this way,our investigation helps us in a better understanding and implementation perspective of the proposed system,as the outcomes of our analysis adds to the precision and accuracy of the entire system.