AIM: To investigate knee awareness and functional outcomes in patients treated with simultaneous bilateral vs unilateral total knee arthroplasty(TKA).METHODS: Through a database search, we identified 210 patients who ...AIM: To investigate knee awareness and functional outcomes in patients treated with simultaneous bilateral vs unilateral total knee arthroplasty(TKA).METHODS: Through a database search, we identified 210 patients who had undergone unilateral TKA(UTKA) and 65 patients who had undergone simultaneous bilateral TKA(SBTKA) at our institution between 2010 and 2012. All TKAs were cemented and cruciate retaining. The mean follow-up period was 3.2(2 to 4) years. All the patients had symptomatic and debilitating unilateral or bilateral osteoarthritis for which all conservative and non-surgical treatments were failed, thus preoperatively the patients had poor functionality. All patients were asked to complete Forgotten Joint Score(FJS) and Oxford Knee Score(OKS) questionnaires. The patients were matched according to age, gender, year of surgery, Kellgren-Lawrence score and pre- andpostoperative overall knee alignment. The FJS and OKS questionnaire results of the two groups were then compared. RESULTS: A mixed-effects model was used to analyze differences between SBTKA and UTKA. OKS: The mean difference in the OKS between the patients who had undergone SBTKA and those who had undergone UTKA was 1.5, which was not statistically significant(CI =-0.9:4.0, P-value = 0.228). The mean OKS of the SBTKA patients was 37.6(SD = 9.0), and the mean OKS of the UTKA patients was 36.1(SD = 9.9). FJS: The mean difference in the FJS between the patients who had undergone SBTKA and those who had undergone UTKA was 2.3, which was not statistically significant(CI =-6.2:10.8, P-value = 0.593). The mean FJS of the SBTKA patients was 59.9(SD = 27.5), and the mean FJS of the UTKA patients was 57.5(SD = 28.8). CONCLUSION: SBTKA and UTKA patients exhibited similar joint functionality and knee awareness. Our results support the use of SBTKA in selected patients suffering from clinically symptomatic bilateral osteoarthritis.展开更多
目的评价重组人促红细胞生成素(recombinant human erythropoietin,r Hu EPO)短期快速应用对同期双侧全膝关节置换术围手术期输血的作用及安全性。方法回顾性分析2013年1月至2015年11月大连医科大学附属第二医院关节外科收治的行同期双...目的评价重组人促红细胞生成素(recombinant human erythropoietin,r Hu EPO)短期快速应用对同期双侧全膝关节置换术围手术期输血的作用及安全性。方法回顾性分析2013年1月至2015年11月大连医科大学附属第二医院关节外科收治的行同期双侧全膝关节置换的患者72例,根据资料完整程度最终选入63例。所有患者入院后均给予多糖铁复合物胶囊补充铁剂。治疗组30例患者于术前3~5 d使用r Hu EPO(10000 IU皮下注射,隔日1次,共7次);对照组33例不给予其他治疗。观察两组患者围手术期输血情况、不良反应、术前及术后2、4、7天血红蛋白(Hb)、红细胞压积(HCT)变化。结果治疗组围手术期输血率(23.33%)低于对照组(48.48%),输血量(2.29±0.78)U小于对照组(3.81±0.94)U,差异均有统计学意义,P<0.05。治疗组术后2、4、7天的Hb及HCT均高于对照组,差异有统计学意义,P<0.05。两组术后不良反应及并发症发生情况比较,差异无统计学意义,P>0.05。结论同期双侧全膝关节置换术患者在围手术期短期快速应用r Hu EPO可显著降低输血率及平均输血量,且临床应用较为安全,可考虑临床广泛推广。展开更多
文摘AIM: To investigate knee awareness and functional outcomes in patients treated with simultaneous bilateral vs unilateral total knee arthroplasty(TKA).METHODS: Through a database search, we identified 210 patients who had undergone unilateral TKA(UTKA) and 65 patients who had undergone simultaneous bilateral TKA(SBTKA) at our institution between 2010 and 2012. All TKAs were cemented and cruciate retaining. The mean follow-up period was 3.2(2 to 4) years. All the patients had symptomatic and debilitating unilateral or bilateral osteoarthritis for which all conservative and non-surgical treatments were failed, thus preoperatively the patients had poor functionality. All patients were asked to complete Forgotten Joint Score(FJS) and Oxford Knee Score(OKS) questionnaires. The patients were matched according to age, gender, year of surgery, Kellgren-Lawrence score and pre- andpostoperative overall knee alignment. The FJS and OKS questionnaire results of the two groups were then compared. RESULTS: A mixed-effects model was used to analyze differences between SBTKA and UTKA. OKS: The mean difference in the OKS between the patients who had undergone SBTKA and those who had undergone UTKA was 1.5, which was not statistically significant(CI =-0.9:4.0, P-value = 0.228). The mean OKS of the SBTKA patients was 37.6(SD = 9.0), and the mean OKS of the UTKA patients was 36.1(SD = 9.9). FJS: The mean difference in the FJS between the patients who had undergone SBTKA and those who had undergone UTKA was 2.3, which was not statistically significant(CI =-6.2:10.8, P-value = 0.593). The mean FJS of the SBTKA patients was 59.9(SD = 27.5), and the mean FJS of the UTKA patients was 57.5(SD = 28.8). CONCLUSION: SBTKA and UTKA patients exhibited similar joint functionality and knee awareness. Our results support the use of SBTKA in selected patients suffering from clinically symptomatic bilateral osteoarthritis.
文摘目的评价重组人促红细胞生成素(recombinant human erythropoietin,r Hu EPO)短期快速应用对同期双侧全膝关节置换术围手术期输血的作用及安全性。方法回顾性分析2013年1月至2015年11月大连医科大学附属第二医院关节外科收治的行同期双侧全膝关节置换的患者72例,根据资料完整程度最终选入63例。所有患者入院后均给予多糖铁复合物胶囊补充铁剂。治疗组30例患者于术前3~5 d使用r Hu EPO(10000 IU皮下注射,隔日1次,共7次);对照组33例不给予其他治疗。观察两组患者围手术期输血情况、不良反应、术前及术后2、4、7天血红蛋白(Hb)、红细胞压积(HCT)变化。结果治疗组围手术期输血率(23.33%)低于对照组(48.48%),输血量(2.29±0.78)U小于对照组(3.81±0.94)U,差异均有统计学意义,P<0.05。治疗组术后2、4、7天的Hb及HCT均高于对照组,差异有统计学意义,P<0.05。两组术后不良反应及并发症发生情况比较,差异无统计学意义,P>0.05。结论同期双侧全膝关节置换术患者在围手术期短期快速应用r Hu EPO可显著降低输血率及平均输血量,且临床应用较为安全,可考虑临床广泛推广。
