The relatively uniform bismuth-copper film was electrodeposited between -15 and -20 mV in the sulfate electrolyte containing 4 mmol/L bismuth ion and 2 mmol/L copper ion.Only copper was electrodeposited at -5 mV.The d...The relatively uniform bismuth-copper film was electrodeposited between -15 and -20 mV in the sulfate electrolyte containing 4 mmol/L bismuth ion and 2 mmol/L copper ion.Only copper was electrodeposited at -5 mV.The dendritic bismuth-copper film was electrodeposited under -20 mV.The cathodic current became constant between -20 and -400 mV.Therefore,bismuth-copper electrodeposition changes from charge transfer controlling to diffusion controlling at -20 mV.On the other hand,the uniform bismuth-copper film was electrodeposited between -5 and -35 mV in the methanesulfonate electrolyte containing 4 mmol/L bismuth ion and 2 mmol/L copper ion.The dendritic bismuth-copper film was electrodeposited under -35 mV.The potential region for good electrodepositon in methanesulfonate electrolyte is wider than that in sulfate electrolyte.Therefore,it is easy to control electrodeposition conditions by using methanesulfonate electrolyte.展开更多
The doping of radiocontrast agent such as bismuth（Bi） in copper chalcogenide nanocrystals for computed tomography（CT） imaging guided photothermal therapy（PTT） has drawn increasing attention. However, the doping ...The doping of radiocontrast agent such as bismuth（Bi） in copper chalcogenide nanocrystals for computed tomography（CT） imaging guided photothermal therapy（PTT） has drawn increasing attention. However, the doping of Bi often suffers from the weak CT signal due to the low Bi doping concentration and deteriorates the PTT efficacy of copper chalcogenides. Here we report a multifunctional nanoprobe by encapsulating both Cu_（1.94） S and Bi_2S_3 nanocrystals into a biocompatible poly（amino acid） matrix with size of^85 nm for CT imaging guided PTT. The amount of nanocrystals and the ratio of Cu1.94S-to-Bi2S3 in the multifunctional nanocomposites（NCs） are tunable toward both high photothermal conversion efficiency（~31%） and excellent CT imaging capability（27.8 HU g L^（-1））. These NCs demonstrate excellent effects for photothermal ablation of tumors after intratumoral injection on 4T1 tumor-bearing mice. Our study may provide a facile strategy for the fabrication of multifunctional theranostics towards simultaneous strong CT signal and excellent PTT.展开更多
文摘The relatively uniform bismuth-copper film was electrodeposited between -15 and -20 mV in the sulfate electrolyte containing 4 mmol/L bismuth ion and 2 mmol/L copper ion.Only copper was electrodeposited at -5 mV.The dendritic bismuth-copper film was electrodeposited under -20 mV.The cathodic current became constant between -20 and -400 mV.Therefore,bismuth-copper electrodeposition changes from charge transfer controlling to diffusion controlling at -20 mV.On the other hand,the uniform bismuth-copper film was electrodeposited between -5 and -35 mV in the methanesulfonate electrolyte containing 4 mmol/L bismuth ion and 2 mmol/L copper ion.The dendritic bismuth-copper film was electrodeposited under -35 mV.The potential region for good electrodepositon in methanesulfonate electrolyte is wider than that in sulfate electrolyte.Therefore,it is easy to control electrodeposition conditions by using methanesulfonate electrolyte.
基金upported in part by the National Natural Science Foundation of China(21475007 and 21675009)the Fundamental Research Funds for the Central Universities(buctrc201608 and buctrc201720)
文摘The doping of radiocontrast agent such as bismuth（Bi） in copper chalcogenide nanocrystals for computed tomography（CT） imaging guided photothermal therapy（PTT） has drawn increasing attention. However, the doping of Bi often suffers from the weak CT signal due to the low Bi doping concentration and deteriorates the PTT efficacy of copper chalcogenides. Here we report a multifunctional nanoprobe by encapsulating both Cu_（1.94） S and Bi_2S_3 nanocrystals into a biocompatible poly（amino acid） matrix with size of^85 nm for CT imaging guided PTT. The amount of nanocrystals and the ratio of Cu1.94S-to-Bi2S3 in the multifunctional nanocomposites（NCs） are tunable toward both high photothermal conversion efficiency（~31%） and excellent CT imaging capability（27.8 HU g L^（-1））. These NCs demonstrate excellent effects for photothermal ablation of tumors after intratumoral injection on 4T1 tumor-bearing mice. Our study may provide a facile strategy for the fabrication of multifunctional theranostics towards simultaneous strong CT signal and excellent PTT.
