目的探讨研究美国国立综合癌症网络（National Comprehensive Cancer Network,NCCN）心理痛苦干预对中晚期肺癌患者行为功能状态和生活质量的影响。方法选取我院2012年3月~2015年11月收治确诊的154例中晚期肺癌病患,对纳入研究的全体患...目的探讨研究美国国立综合癌症网络（National Comprehensive Cancer Network,NCCN）心理痛苦干预对中晚期肺癌患者行为功能状态和生活质量的影响。方法选取我院2012年3月~2015年11月收治确诊的154例中晚期肺癌病患,对纳入研究的全体患者采取随机数字表法将其平均分成观察组与对照组,每组各77例。其中对照组实施常规性护理,观察组则在此护理基础上施以NCCN心理痛苦干预,观察比较两组患者的护理前后的行为功能状态量表（KPS）评分,心理痛苦温度计（DT）评分与心理痛苦相关因素调查表（PL）评分、生命质量测定量表（QLQ-C30）评分。结果两组患者实施护理干预前上述量表评分组间比较差异无统计学意义（P〉0.05）;实施护理干预后上每组患者的上述量表评分均较干预前明显好转,且差异有统计学意义（P〈0.05）;观察组干预后KPS评分、PL评分及DT的痛苦检出率均明显较对照组为优（P〈0.05）。两组患者护理干预后QLQ-C30评分中,只有经济困难维度评分组间比较差异无统计学意义（P〉0.05）,剩余各项评分观察组较对照组均显著为优（P〈0.05）。结论 NCCN心理痛苦干预可更有效的缓解中晚期肺癌的痛苦,改善其生活质量与行为功能状态。展开更多
Alzheimer's disease(AD)is the most common cognitive disorder in the elderly.Its main clinical manifestations are cognitive decline(C),behavioral and psychological symptoms(B),and a decline in the activities of dai...Alzheimer's disease(AD)is the most common cognitive disorder in the elderly.Its main clinical manifestations are cognitive decline(C),behavioral and psychological symptoms(B),and a decline in the activities of daily living(A),also known as ABC symptoms.Early identification and evaluation of ABC symptoms are helpful for establishing the accurate diagnosis,comprehensive treatment,and prognosis of AD.To guide Chinese clinical practice for optimization of the comprehensive management of AD,in 2018,The Academy of Cognitive Disorder of China gathered 22 neurologists and gerontologists in China to build a consensus on the comprehensive management of AD.Based on a review of the evidence,the consensus summarizes the pathogenesis,pathological changes,clinical manifestations,evaluation,diagnosis,drug and non-drug treatment,and patient care for AD.Focus group discussion was used to establish a flowchart of comprehensive ABC management for AD patients.The new consensus provides a feasible AD management process for clinicians.展开更多
目的探讨基于中医情志护理的持续沟通联合耳穴压豆在精神分裂症患者中的护理效果。方法选择2020年1月至2021年12月在长沙市某三甲医院收治的精神分裂症患者98例,随机分为观察组和对照组,各49例。两组患者均予以奥氮平片,5~20 mg/d,1次/d...目的探讨基于中医情志护理的持续沟通联合耳穴压豆在精神分裂症患者中的护理效果。方法选择2020年1月至2021年12月在长沙市某三甲医院收治的精神分裂症患者98例,随机分为观察组和对照组,各49例。两组患者均予以奥氮平片,5~20 mg/d,1次/d,对照组行常规心理疏导及健康宣教,观察组给予基于中医情志护理的持续沟通联合耳穴压豆,两组疗程均为8周。采用精神病评估量表(brief psychiatric rating scale,BPRS)评估两组患者精神病症状、社会功能评定量表(scale of social function of psychosis inpatients,SSFPI)评估社会功能改善情况、住院病人观察量表(nurses'observation scale for inpatient evaluation,NOSIE)评估行为障碍程度,并记录危险发生情况,比较两组患者护理效果。结果干预后,观察组BPRS评分低于对照组,差异有统计学意义(P<0.05);观察组SSFPI评分、NOSIE积极方面评分均高于对照组,差异有统计学意义(P<0.05);观察组NOSIE量表消极方面评分及危险行为发生率均低于对照组,差异有统计学意义(P<0.05)。结论基于中医情志护理的持续沟通联合耳穴压豆可有效改善精神分裂症患者的精神症状、社会功能及行为障碍,并降低其危险行为发生率,值得临床推广应用。展开更多
The present study investigated the effects of catalpol, the main constituent of the Chinese herb Rehmannia root, on neurons following brain ischemia, A rat model of focal permanent brain ischemia was established using...The present study investigated the effects of catalpol, the main constituent of the Chinese herb Rehmannia root, on neurons following brain ischemia, A rat model of focal permanent brain ischemia was established using electrocoagulation, The rats were intrapedtoneally injected with catalpol, at a dose of 5 mg/kg, daily for 1 week, Results showed that the number of neuronal synapses in the motor cortex and growth associated protein 43 expression were increased following catalpol treatment, indicating that catalpol might contribute to neuroplasticity and ameliorate functional neurological deficits induced by cerebral ischemia.展开更多
文摘目的探讨研究美国国立综合癌症网络（National Comprehensive Cancer Network,NCCN）心理痛苦干预对中晚期肺癌患者行为功能状态和生活质量的影响。方法选取我院2012年3月~2015年11月收治确诊的154例中晚期肺癌病患,对纳入研究的全体患者采取随机数字表法将其平均分成观察组与对照组,每组各77例。其中对照组实施常规性护理,观察组则在此护理基础上施以NCCN心理痛苦干预,观察比较两组患者的护理前后的行为功能状态量表（KPS）评分,心理痛苦温度计（DT）评分与心理痛苦相关因素调查表（PL）评分、生命质量测定量表（QLQ-C30）评分。结果两组患者实施护理干预前上述量表评分组间比较差异无统计学意义（P〉0.05）;实施护理干预后上每组患者的上述量表评分均较干预前明显好转,且差异有统计学意义（P〈0.05）;观察组干预后KPS评分、PL评分及DT的痛苦检出率均明显较对照组为优（P〈0.05）。两组患者护理干预后QLQ-C30评分中,只有经济困难维度评分组间比较差异无统计学意义（P〉0.05）,剩余各项评分观察组较对照组均显著为优（P〈0.05）。结论 NCCN心理痛苦干预可更有效的缓解中晚期肺癌的痛苦,改善其生活质量与行为功能状态。
文摘Alzheimer's disease(AD)is the most common cognitive disorder in the elderly.Its main clinical manifestations are cognitive decline(C),behavioral and psychological symptoms(B),and a decline in the activities of daily living(A),also known as ABC symptoms.Early identification and evaluation of ABC symptoms are helpful for establishing the accurate diagnosis,comprehensive treatment,and prognosis of AD.To guide Chinese clinical practice for optimization of the comprehensive management of AD,in 2018,The Academy of Cognitive Disorder of China gathered 22 neurologists and gerontologists in China to build a consensus on the comprehensive management of AD.Based on a review of the evidence,the consensus summarizes the pathogenesis,pathological changes,clinical manifestations,evaluation,diagnosis,drug and non-drug treatment,and patient care for AD.Focus group discussion was used to establish a flowchart of comprehensive ABC management for AD patients.The new consensus provides a feasible AD management process for clinicians.
文摘目的探讨基于中医情志护理的持续沟通联合耳穴压豆在精神分裂症患者中的护理效果。方法选择2020年1月至2021年12月在长沙市某三甲医院收治的精神分裂症患者98例,随机分为观察组和对照组,各49例。两组患者均予以奥氮平片,5~20 mg/d,1次/d,对照组行常规心理疏导及健康宣教,观察组给予基于中医情志护理的持续沟通联合耳穴压豆,两组疗程均为8周。采用精神病评估量表(brief psychiatric rating scale,BPRS)评估两组患者精神病症状、社会功能评定量表(scale of social function of psychosis inpatients,SSFPI)评估社会功能改善情况、住院病人观察量表(nurses'observation scale for inpatient evaluation,NOSIE)评估行为障碍程度,并记录危险发生情况,比较两组患者护理效果。结果干预后,观察组BPRS评分低于对照组,差异有统计学意义(P<0.05);观察组SSFPI评分、NOSIE积极方面评分均高于对照组,差异有统计学意义(P<0.05);观察组NOSIE量表消极方面评分及危险行为发生率均低于对照组,差异有统计学意义(P<0.05)。结论基于中医情志护理的持续沟通联合耳穴压豆可有效改善精神分裂症患者的精神症状、社会功能及行为障碍,并降低其危险行为发生率,值得临床推广应用。
基金the National Natural Science Foundation of China, No. 81073084the Fundamental Research Funds for the Central Universities, No.XDJK2009C081+1 种基金the Natural Science Foundation Project of CQ CSTC, No.2010BB5127Science and Technology Innovative Capacity Construction Program of Chongqing(CSTC) No.2009CB1010
文摘The present study investigated the effects of catalpol, the main constituent of the Chinese herb Rehmannia root, on neurons following brain ischemia, A rat model of focal permanent brain ischemia was established using electrocoagulation, The rats were intrapedtoneally injected with catalpol, at a dose of 5 mg/kg, daily for 1 week, Results showed that the number of neuronal synapses in the motor cortex and growth associated protein 43 expression were increased following catalpol treatment, indicating that catalpol might contribute to neuroplasticity and ameliorate functional neurological deficits induced by cerebral ischemia.
