Objective The occurrence characteristic of Kashin Beck Disease (KBD) in pedigrees ascertained on the basis of one proband was estimated. Methods A total of 255 individuals in 40 pedigrees were collected from areas ...Objective The occurrence characteristic of Kashin Beck Disease (KBD) in pedigrees ascertained on the basis of one proband was estimated. Methods A total of 255 individuals in 40 pedigrees were collected from areas in the Shaanxi Province. Results ① Parents and siblings of index cases have a 3-4 times higher risk than a random unrelated individual. The odds ratio for disease is higher in mothers than in fathers of index cases; ② Prevalence in relatives of index cases (K r= 59.2% ) greatly exceeds population prevalence (K= 17.5% ); ③ K r increases with sibship size; ④ There is no significant difference of K r for male and female siblings of index cases. Also, population prevalence is not sex specific. Conclusion In conjunction with environmental agents, genetics may play an important role in KBD etiology.展开更多
AIM: To investigate the prevalence of erectile dysfunction(ED) and its association with depression in patients with chronic viral hepatitis.METHODS: This single center cross-sectional study was conducted from August 2...AIM: To investigate the prevalence of erectile dysfunction(ED) and its association with depression in patients with chronic viral hepatitis.METHODS: This single center cross-sectional study was conducted from August 2013 through January 2014. All outpatients with chronic viral hepatitis in our liver clinic between 18 and 80 years of age were considered eligible for this study. The exclusion criteria included well-established causes of ED, such as diabetes, hypertension, hyperlipidemia, alcohol abuse, liver cirrhosis, ischemic heart disease, renal disease, neurologic disease, and malignancy. We also excluded the patients who had incompletely answered the questionnaires. ED was assessed using the validated Korean version of the International Index of Erectile Function(IIEF-5) scale. The Korean version of the self-administered Beck Depression Inventory(BDI) scale was used to assess depression in the patients. Demographic and medical data were obtained from the patients' medical records. Current or past history of psychiatric diagnosis and drug history including the use of an antiviral agent and an antidepressant were also recorded. RESULTS: A total of 727 patients met the initial eligibility criteria. Six hundred seventeen patients were excluded because their medical records contained one or more of the previously determined exclusion criteria. The remaining 110 patients were assessed based on the BDI and IIEF-5 questionnaires. Based on the IIEF-5 scale, the prevalence of ED among patients with chronic viral hepatitis was 40%. Compared with the non-ED group, patients in the ED group were older. The proportion of patients in the ED group who had a job or who were na?ve peg-interferon users was lower than that in patients in the non-ED group. Patients with ED had significantly lower scores on the IIEF-5 scale than patients without ED(11.75 ± 4.88 vs 21.33 ± 1.86, P = 0.000). Patients with ED rated significantly higher scores on the BDI scale compared with patients without ED(12.59 ± 7.08 vs 5.30 ± 4.00, P = 0.000)展开更多
Objective： To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals....Objective： To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals. Methods： In this double blind, cross-over trial, 30 obese subjects were randomized to receive either curcumin （1 g/day） or placebo for a period of 30 days. Following a wash-out interval of 2 weeks, each subject was crossed over to the alternative regimen for a further 30 days. Severity of anxiety and depression was assessed at baseline and at weeks 4, 6 and 10 of the trial using the Beck Anxiety Inventory （BAI） and Beck Depression Inventory （BDI） scales, respectively. Results： Mean BAI score was found to be significantly reduced following curcumin therapy （P=0.03）. However, curcumin supplementation did not exert any significant impact on BDI scores （P=0.7）. Conclusion： Curcumin has a potential anti-anxiety effect in individuals with obesity.展开更多
In this paper, we study the upper bounds for ruin probabilities of an insurance company which invests its wealth in a stock and a bond. We assume that the interest rate of the bond is stochastic and it is described by...In this paper, we study the upper bounds for ruin probabilities of an insurance company which invests its wealth in a stock and a bond. We assume that the interest rate of the bond is stochastic and it is described by a Cox-Ingersoll-Ross （CIR） model. For the stock price process, we consider both the case of constant volatility （driven by an O U process） and the case of stochastic volatility （driven by a CIR model）. In each case, under certain conditions, we obtain the minimal upper bound for ruin probability as well as the corresponding optimal investment strategy by a pure probabilistic method.展开更多
BACKGROUND Medical school is known for its lengthy process,which is both physically and emotionally draining.Students’mental balance would shrink as they progress in their medical training.A systematic review and met...BACKGROUND Medical school is known for its lengthy process,which is both physically and emotionally draining.Students’mental balance would shrink as they progress in their medical training.A systematic review and meta-analysis reported that the prevalence of depressive symptoms among medical students remained relatively constant at 27.2%.AIM To assess the prevalence of depressive symptoms among Tunisian medical students and evaluate its associated factors.METHODS This is a descriptive cross-sectional study that was carried out in the second semester of the academic year 2017/2018,between April 2018 and July 2018 among 1138 medical students.Data were collected using a socio-demographic questionnaire and the Beck Depression Inventory-II(BDI-II).RESULTS Sixty-four percent(n=728)of the participants had depressive symptoms,of which 266(23.4%)met the criteria for mild,271(23.8%)for moderate,and 191(16.8%)for severe depressive symptoms.Female gender,low socio-economic level,smoking habits and history of mental disorder,performing leisure and physical activities,satisfaction toward a career choice,and happiness perception were the main prognostic factors for depression among medical students.Although academic grades may not be considered a prognostic factor,final-year students appeared to be less depressive than their colleagues.CONCLUSION These findings give insight into mental health issues and comorbidities among Tunisian medical students.It is a hopeful request for decision-makers and academic authorities to set serious measures and draw effective interventions to minimize the currency of psychological distress among this subpopulation.展开更多
BACKGROUND According to the trend of global population aging,the proportion of elderly patients with chronic kidney disease(CKD)is expected to increase.However,there are more than 20 million people in China with decom...BACKGROUND According to the trend of global population aging,the proportion of elderly patients with chronic kidney disease(CKD)is expected to increase.However,there are more than 20 million people in China with decompensated kidney function,of which 19.25%are elderly people.Therefore,special attention should be paid to the education years,sleep quality,anxiety status,comorbidities with diabetes,cardiovascular disease(CVD),and anemia as independent risk factors for depression in elderly CKD patients.This study explores the clinical management of elderly CKD patients that should address these risk factors to prevent depression and improve their prognosis.AIM To investigate depression risk factors in older patients receiving peritoneal dialysis,aiding future prevention of depression in these patients.METHODS This retrospective study included a primary study population of 170 patients with CKD who received peritoneal dialysis from January 2020 to December 2022.We assessed the patients’mental status using the Beck Depression Inventory Score-II(BDI-II),Self-Rating Anxiety Scale(SAS),Anxiety Inventory Score,and the Pittsburgh Sleep Quality Index(PSQI).Logistic regression was employed to identify depression independent risk factors among these patients.RESULTS The non-depressed group had a significantly longer education period than the depressed group(P<0.05).The depressed group exhibited significantly higher mental status scores than the non-depressed group(P<0.001).Patients with diabetes mellitus(DM)or CVD had a higher probability of developing depression.Patients with depression had significantly lower hemoglobin and albumin levels than patients without depression(P<0.05).Spearman correlation analysis of BDI-II scale scores,measuring depression,indicated positive correlations with BDI-II and SAS scores as risk factors for depression in patients with CKD.In contrast,years of education,hemoglobin levels,and peritoneal Kt/V were negatively correlated,serving as protective factors against depression.An analysis of vari展开更多
Kaschin-Beck disease (KBD) could be exogeneous free radical induced endemic osteoarthropathy under conditions of lacking necessary antioxidant defences.especially selenium-cored defence in Chinese eco-en-vironment. Ex...Kaschin-Beck disease (KBD) could be exogeneous free radical induced endemic osteoarthropathy under conditions of lacking necessary antioxidant defences.especially selenium-cored defence in Chinese eco-en-vironment. Experimental evidences have been provided for the internal relations among previously suggested pathologic factors, i.e., selenium deficiency, organic matters of drinking waterand mycotoxins from contaminated grains, based on the facts that the former is a preventory factor while the others are exogenous freeradical carriers. ESR spectrum shows that these exogenous free radical carriers have a property of semi-quinone compounds and are toxic in in-vitro cartilage cell culture and animal tests in inducing lipid peroxidation process.展开更多
Background: Stroke ranks third and is the leading cause of permanent disability in western countries. Furthermore there are no treatments for the psychosocial effects of this pathology. Purpose: Analyse the effect of ...Background: Stroke ranks third and is the leading cause of permanent disability in western countries. Furthermore there are no treatments for the psychosocial effects of this pathology. Purpose: Analyse the effect of an aquatic exercise program in depression and trace and state anxiety in subjects who suffered an ischemic stroke. Methods: Two groups were analyzed: experimental group (EG) n = 15, 50.3 ± 9.1 years;control group (CG) n = 13, 52.5 ± 7.7 years. EG underwent a 12-week aquatic exercise program. Both groups were evaluated in pre and post- treatment using Beck Depression Inventory (BDI) and Trace State Anxiety Inventory (IDATE). Wilcoxon signed-rank and Mann-Whitney tests were used to compare moments and groups, respec- tively. Results: The BDI scores of aquatic activities were: pre-treatment, 17.4 ± 7.7 and 16.9 ± 8.6 for the EG and CG, respectively;post-treat- ment, 13.2 + 7.1 and 16.4 + 7.9 for the EG and CG, respectively. The IDATE scores for anxiety trace in strength training were: pre-treatment, 43.2 + 12.5 and 42.9 + 12.2 for the EG and CG, respec- tively;post-treatment, 39.7 + 7.1 and 42.6 + 12.1 for the EG and CG, respectively. The IDATE scores for anxiety state in strength training were: pre-treatment, 46.9 + 7.6 and 47.4 + 8.1 for the EG and CG, respectively;post-treatment, 44.4 + 7.9 and 47.5 + 8.0 for the EG and CG, respectively. Significant differences were found in pre and post-treatment values in the EG and between groups in the depression and trace and state anxiety levels in post-treatment (p Conclusions: Aquatic physical activity contributes to an improvement of the levels of depression and anxiety in people who suffered a stroke.展开更多
Background: It is well known that depression is effective upon the occurrence of hypertension. The aim was to determine the prevalence of depression in the population aged 30 years old and over, and its impact on hype...Background: It is well known that depression is effective upon the occurrence of hypertension. The aim was to determine the prevalence of depression in the population aged 30 years old and over, and its impact on hypertension. Methods: This study is a cross-sectional study conducted on people aged 30 years and over between Sep., 1st and Oct., 30th 2009 in a region of western Turkey, Eskisehir. The questionnaire included the information about the subjects’ sociodemographic characteristics and the Beck Depression Inventory (BDI) used to determine those who were at the risk of depression. The data were analyzed using Student’s t test, Chi-square test and Logistic regression analysis. A value of p < 0.05 was considered statistically significant. Results: According to the Logistic analysis, older age (OR = 16.050), adding extra salt to meals (OR = 2.079), obesity (OR = 2.170) and family history of hypertension (OR = 2.139) were the important risk factors for hypertension (p < 0.05 for each one). It was determined that there was a positive connection between the scores received from the BDI and systolic and diastolic BP values [(rs = 0.151;p < 0.001) and (rs = 0.146;p < 0.001)], respectively. Conclusion: According to the above results, we may conclude that depression is effective upon the occurrence of hypertension.展开更多
This study is to acquire the relationship between organic substances in water and prevalence of Kashin Beck disease (KBD). We sampled in three endemic areas and their corresponding neighboring non endemic areas, det...This study is to acquire the relationship between organic substances in water and prevalence of Kashin Beck disease (KBD). We sampled in three endemic areas and their corresponding neighboring non endemic areas, determined the contents of organic substances and examined the children. The results showed that:①humus type B exited only in endemic areas; ②the content of humus type B is proportional to the state of the illness. KBD may be related to the humus type B in drinking water.展开更多
Objectives: This study investigated the relationship between depression and obesity in severely obese retired individuals using the case-control method. Methods: The subject group consisted of 112 individuals receivin...Objectives: This study investigated the relationship between depression and obesity in severely obese retired individuals using the case-control method. Methods: The subject group consisted of 112 individuals receiving a permanent disability pension primarily due to obesity. The prevalence of depression was measured with a personal psychiatric interview and the Beck Depression Inventory (21). Male and female controls were selected separately, with five controls for male subjects and three controls for female subjects. The controls were matched with the subjects according to place of residence, age, time that pension was granted, and occupation. The statistical analyses included χ2 tests, means, t-tests for paired variables, a conditional logistic linear model, correlation coefficients and the percent distributions. Results: Depression was diagnosed more often in the subject group than in the control group according to the psychiatric interview. Based on the conditional logistic linear model, individuals with severe obesity had a higher risk of depression than those in the control group. The most common disturbance was chronic depression in both groups. Additionally, there were significant findings regarding the outcome of depression for every classification in the psychiatric interview. According to the Beck Depression Inventory, depression was more common in subjects than in controls. However, slight depression was most common in the study group. Seven percent of the subjects had masked depression. The questions on the Beck Depression Inventory that measure irritability, indecisiveness, body image and ability to work were nearly significant. Regarding weight changes, the Beck Depression Inventory questions on both weight loss (p = 0.014) and weight gain (p = 0.017) were statistically significant. In the study group, individuals with BMI over 40 kg/m2 gained the most weight;however, weight loss was very low overall. Regarding changes in appetite, the majority of the study group responded that they had a poorer a展开更多
文摘Objective The occurrence characteristic of Kashin Beck Disease (KBD) in pedigrees ascertained on the basis of one proband was estimated. Methods A total of 255 individuals in 40 pedigrees were collected from areas in the Shaanxi Province. Results ① Parents and siblings of index cases have a 3-4 times higher risk than a random unrelated individual. The odds ratio for disease is higher in mothers than in fathers of index cases; ② Prevalence in relatives of index cases (K r= 59.2% ) greatly exceeds population prevalence (K= 17.5% ); ③ K r increases with sibship size; ④ There is no significant difference of K r for male and female siblings of index cases. Also, population prevalence is not sex specific. Conclusion In conjunction with environmental agents, genetics may play an important role in KBD etiology.
文摘AIM: To investigate the prevalence of erectile dysfunction(ED) and its association with depression in patients with chronic viral hepatitis.METHODS: This single center cross-sectional study was conducted from August 2013 through January 2014. All outpatients with chronic viral hepatitis in our liver clinic between 18 and 80 years of age were considered eligible for this study. The exclusion criteria included well-established causes of ED, such as diabetes, hypertension, hyperlipidemia, alcohol abuse, liver cirrhosis, ischemic heart disease, renal disease, neurologic disease, and malignancy. We also excluded the patients who had incompletely answered the questionnaires. ED was assessed using the validated Korean version of the International Index of Erectile Function(IIEF-5) scale. The Korean version of the self-administered Beck Depression Inventory(BDI) scale was used to assess depression in the patients. Demographic and medical data were obtained from the patients' medical records. Current or past history of psychiatric diagnosis and drug history including the use of an antiviral agent and an antidepressant were also recorded. RESULTS: A total of 727 patients met the initial eligibility criteria. Six hundred seventeen patients were excluded because their medical records contained one or more of the previously determined exclusion criteria. The remaining 110 patients were assessed based on the BDI and IIEF-5 questionnaires. Based on the IIEF-5 scale, the prevalence of ED among patients with chronic viral hepatitis was 40%. Compared with the non-ED group, patients in the ED group were older. The proportion of patients in the ED group who had a job or who were na?ve peg-interferon users was lower than that in patients in the non-ED group. Patients with ED had significantly lower scores on the IIEF-5 scale than patients without ED(11.75 ± 4.88 vs 21.33 ± 1.86, P = 0.000). Patients with ED rated significantly higher scores on the BDI scale compared with patients without ED(12.59 ± 7.08 vs 5.30 ± 4.00, P = 0.000)
基金Support by the Research Council at the Mashhad University of Medical Sciences,Mashhad,Iran
文摘Objective： To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals. Methods： In this double blind, cross-over trial, 30 obese subjects were randomized to receive either curcumin （1 g/day） or placebo for a period of 30 days. Following a wash-out interval of 2 weeks, each subject was crossed over to the alternative regimen for a further 30 days. Severity of anxiety and depression was assessed at baseline and at weeks 4, 6 and 10 of the trial using the Beck Anxiety Inventory （BAI） and Beck Depression Inventory （BDI） scales, respectively. Results： Mean BAI score was found to be significantly reduced following curcumin therapy （P=0.03）. However, curcumin supplementation did not exert any significant impact on BDI scores （P=0.7）. Conclusion： Curcumin has a potential anti-anxiety effect in individuals with obesity.
基金Supported by National Basic Research Program of China (973 Program, Grant No. 2007CB814905)National Natural Science Foundation of China (Grant No. 10871102)
文摘In this paper, we study the upper bounds for ruin probabilities of an insurance company which invests its wealth in a stock and a bond. We assume that the interest rate of the bond is stochastic and it is described by a Cox-Ingersoll-Ross （CIR） model. For the stock price process, we consider both the case of constant volatility （driven by an O U process） and the case of stochastic volatility （driven by a CIR model）. In each case, under certain conditions, we obtain the minimal upper bound for ruin probability as well as the corresponding optimal investment strategy by a pure probabilistic method.
文摘BACKGROUND Medical school is known for its lengthy process,which is both physically and emotionally draining.Students’mental balance would shrink as they progress in their medical training.A systematic review and meta-analysis reported that the prevalence of depressive symptoms among medical students remained relatively constant at 27.2%.AIM To assess the prevalence of depressive symptoms among Tunisian medical students and evaluate its associated factors.METHODS This is a descriptive cross-sectional study that was carried out in the second semester of the academic year 2017/2018,between April 2018 and July 2018 among 1138 medical students.Data were collected using a socio-demographic questionnaire and the Beck Depression Inventory-II(BDI-II).RESULTS Sixty-four percent(n=728)of the participants had depressive symptoms,of which 266(23.4%)met the criteria for mild,271(23.8%)for moderate,and 191(16.8%)for severe depressive symptoms.Female gender,low socio-economic level,smoking habits and history of mental disorder,performing leisure and physical activities,satisfaction toward a career choice,and happiness perception were the main prognostic factors for depression among medical students.Although academic grades may not be considered a prognostic factor,final-year students appeared to be less depressive than their colleagues.CONCLUSION These findings give insight into mental health issues and comorbidities among Tunisian medical students.It is a hopeful request for decision-makers and academic authorities to set serious measures and draw effective interventions to minimize the currency of psychological distress among this subpopulation.
文摘BACKGROUND According to the trend of global population aging,the proportion of elderly patients with chronic kidney disease(CKD)is expected to increase.However,there are more than 20 million people in China with decompensated kidney function,of which 19.25%are elderly people.Therefore,special attention should be paid to the education years,sleep quality,anxiety status,comorbidities with diabetes,cardiovascular disease(CVD),and anemia as independent risk factors for depression in elderly CKD patients.This study explores the clinical management of elderly CKD patients that should address these risk factors to prevent depression and improve their prognosis.AIM To investigate depression risk factors in older patients receiving peritoneal dialysis,aiding future prevention of depression in these patients.METHODS This retrospective study included a primary study population of 170 patients with CKD who received peritoneal dialysis from January 2020 to December 2022.We assessed the patients’mental status using the Beck Depression Inventory Score-II(BDI-II),Self-Rating Anxiety Scale(SAS),Anxiety Inventory Score,and the Pittsburgh Sleep Quality Index(PSQI).Logistic regression was employed to identify depression independent risk factors among these patients.RESULTS The non-depressed group had a significantly longer education period than the depressed group(P<0.05).The depressed group exhibited significantly higher mental status scores than the non-depressed group(P<0.001).Patients with diabetes mellitus(DM)or CVD had a higher probability of developing depression.Patients with depression had significantly lower hemoglobin and albumin levels than patients without depression(P<0.05).Spearman correlation analysis of BDI-II scale scores,measuring depression,indicated positive correlations with BDI-II and SAS scores as risk factors for depression in patients with CKD.In contrast,years of education,hemoglobin levels,and peritoneal Kt/V were negatively correlated,serving as protective factors against depression.An analysis of vari
文摘Kaschin-Beck disease (KBD) could be exogeneous free radical induced endemic osteoarthropathy under conditions of lacking necessary antioxidant defences.especially selenium-cored defence in Chinese eco-en-vironment. Experimental evidences have been provided for the internal relations among previously suggested pathologic factors, i.e., selenium deficiency, organic matters of drinking waterand mycotoxins from contaminated grains, based on the facts that the former is a preventory factor while the others are exogenous freeradical carriers. ESR spectrum shows that these exogenous free radical carriers have a property of semi-quinone compounds and are toxic in in-vitro cartilage cell culture and animal tests in inducing lipid peroxidation process.
文摘Background: Stroke ranks third and is the leading cause of permanent disability in western countries. Furthermore there are no treatments for the psychosocial effects of this pathology. Purpose: Analyse the effect of an aquatic exercise program in depression and trace and state anxiety in subjects who suffered an ischemic stroke. Methods: Two groups were analyzed: experimental group (EG) n = 15, 50.3 ± 9.1 years;control group (CG) n = 13, 52.5 ± 7.7 years. EG underwent a 12-week aquatic exercise program. Both groups were evaluated in pre and post- treatment using Beck Depression Inventory (BDI) and Trace State Anxiety Inventory (IDATE). Wilcoxon signed-rank and Mann-Whitney tests were used to compare moments and groups, respec- tively. Results: The BDI scores of aquatic activities were: pre-treatment, 17.4 ± 7.7 and 16.9 ± 8.6 for the EG and CG, respectively;post-treat- ment, 13.2 + 7.1 and 16.4 + 7.9 for the EG and CG, respectively. The IDATE scores for anxiety trace in strength training were: pre-treatment, 43.2 + 12.5 and 42.9 + 12.2 for the EG and CG, respec- tively;post-treatment, 39.7 + 7.1 and 42.6 + 12.1 for the EG and CG, respectively. The IDATE scores for anxiety state in strength training were: pre-treatment, 46.9 + 7.6 and 47.4 + 8.1 for the EG and CG, respectively;post-treatment, 44.4 + 7.9 and 47.5 + 8.0 for the EG and CG, respectively. Significant differences were found in pre and post-treatment values in the EG and between groups in the depression and trace and state anxiety levels in post-treatment (p Conclusions: Aquatic physical activity contributes to an improvement of the levels of depression and anxiety in people who suffered a stroke.
文摘Background: It is well known that depression is effective upon the occurrence of hypertension. The aim was to determine the prevalence of depression in the population aged 30 years old and over, and its impact on hypertension. Methods: This study is a cross-sectional study conducted on people aged 30 years and over between Sep., 1st and Oct., 30th 2009 in a region of western Turkey, Eskisehir. The questionnaire included the information about the subjects’ sociodemographic characteristics and the Beck Depression Inventory (BDI) used to determine those who were at the risk of depression. The data were analyzed using Student’s t test, Chi-square test and Logistic regression analysis. A value of p < 0.05 was considered statistically significant. Results: According to the Logistic analysis, older age (OR = 16.050), adding extra salt to meals (OR = 2.079), obesity (OR = 2.170) and family history of hypertension (OR = 2.139) were the important risk factors for hypertension (p < 0.05 for each one). It was determined that there was a positive connection between the scores received from the BDI and systolic and diastolic BP values [(rs = 0.151;p < 0.001) and (rs = 0.146;p < 0.001)], respectively. Conclusion: According to the above results, we may conclude that depression is effective upon the occurrence of hypertension.
文摘This study is to acquire the relationship between organic substances in water and prevalence of Kashin Beck disease (KBD). We sampled in three endemic areas and their corresponding neighboring non endemic areas, determined the contents of organic substances and examined the children. The results showed that:①humus type B exited only in endemic areas; ②the content of humus type B is proportional to the state of the illness. KBD may be related to the humus type B in drinking water.
文摘Objectives: This study investigated the relationship between depression and obesity in severely obese retired individuals using the case-control method. Methods: The subject group consisted of 112 individuals receiving a permanent disability pension primarily due to obesity. The prevalence of depression was measured with a personal psychiatric interview and the Beck Depression Inventory (21). Male and female controls were selected separately, with five controls for male subjects and three controls for female subjects. The controls were matched with the subjects according to place of residence, age, time that pension was granted, and occupation. The statistical analyses included χ2 tests, means, t-tests for paired variables, a conditional logistic linear model, correlation coefficients and the percent distributions. Results: Depression was diagnosed more often in the subject group than in the control group according to the psychiatric interview. Based on the conditional logistic linear model, individuals with severe obesity had a higher risk of depression than those in the control group. The most common disturbance was chronic depression in both groups. Additionally, there were significant findings regarding the outcome of depression for every classification in the psychiatric interview. According to the Beck Depression Inventory, depression was more common in subjects than in controls. However, slight depression was most common in the study group. Seven percent of the subjects had masked depression. The questions on the Beck Depression Inventory that measure irritability, indecisiveness, body image and ability to work were nearly significant. Regarding weight changes, the Beck Depression Inventory questions on both weight loss (p = 0.014) and weight gain (p = 0.017) were statistically significant. In the study group, individuals with BMI over 40 kg/m2 gained the most weight;however, weight loss was very low overall. Regarding changes in appetite, the majority of the study group responded that they had a poorer a
