动物水泡性口炎病毒(VSV)引起动物水泡性疾病。VSV有两个主要抗原群是核酸蛋白和G蛋白抗原。G蛋白因为能产生中和性抗体被认为是在发动抑制病毒感染方面起主要作用。已经证实VSV 的New Jersey 株中产生独立的中和性单克隆抗体的抗原决...动物水泡性口炎病毒(VSV)引起动物水泡性疾病。VSV有两个主要抗原群是核酸蛋白和G蛋白抗原。G蛋白因为能产生中和性抗体被认为是在发动抑制病毒感染方面起主要作用。已经证实VSV 的New Jersey 株中产生独立的中和性单克隆抗体的抗原决定蔟分布在G 蛋白的193~289氨基酸之间。展开更多
The nucleoprotein (NP) gene of rabies CTN strain isolated from China was recombined into pMal-c2x. The antigenicity of the recombined MBP-NP fusion proteins was examined by western blotting and by enzyme linked immuno...The nucleoprotein (NP) gene of rabies CTN strain isolated from China was recombined into pMal-c2x. The antigenicity of the recombined MBP-NP fusion proteins was examined by western blotting and by enzyme linked immunosorbent assay (ELISA). The results demonstrated that the recombined protein possesses predominant antigenicity.展开更多
文摘The nucleoprotein (NP) gene of rabies CTN strain isolated from China was recombined into pMal-c2x. The antigenicity of the recombined MBP-NP fusion proteins was examined by western blotting and by enzyme linked immunosorbent assay (ELISA). The results demonstrated that the recombined protein possesses predominant antigenicity.