BACKGROUND: It has been suggested that addition of obesity score to the APACHE-Ⅱ system can lead to more accurate prediction of severity of acute pancreatitis. However there is scanty information on the usefulness of...BACKGROUND: It has been suggested that addition of obesity score to the APACHE-Ⅱ system can lead to more accurate prediction of severity of acute pancreatitis. However there is scanty information on the usefulness of the combined APACHE-O scoring system in Asian patients. This study aimed to compare the accuracy of Ranson, APACHE-Ⅱ and APACHE-O systems in assessing severity of acute pancreatitis in a local Chinese population. METHODS: One hundred and one consecutive patients with acute pancreatitis were prospectively studied. Body mass index (BMI) was measured on admission. Ranson score, APACHE-Ⅱ and APACHE-O scores were recorded on admission and at 48 hours. By adopting the cut-off levels and definitions advocated in the Atlanta consensus for severe disease, the diagnostic accuracy of the three scoring systems was compared by the area under the curve (AUC) under the receiver operator characteristic curve. RESULTS: Of the 101 patients, 12 (11.9%) patients suffered from severe pancreatitis. Obesity was uncommon and only two patients (2.0%) had BMI >30. Eighty-two (81.2%) patients were normal weight (BMI≤25) whereas 17 (16.8%) were overweight ( BMI 25-30 ). Overweight or obesity (BMI >25) was not associated with severe pancreatitis (P= 0.40). The AUC for admission scores of Ranson, APACHE-Ⅱ, and APACHE-O systems was 0. 549, 0. 904 and 0. 904, respectively. The AUC for 48-hour scores of Ranson, APACHE-Ⅱ and APACHE-O systems was 0.808, 0.955 and 0.951, respectively. CONCLUSIONS: The APACHE-Ⅱ scoring system is more accurate than the Ranson scoring system of the prediction of severity in acute pancreatitis. Addition of obesity score does not significantly improve the predictive accuracy of the APACHE-Ⅱ system in our local population with a low prevalence of obesity.展开更多
目的比较改良早期预警评分(modified early warning score,MEWS)与急性生理和慢性健康评分系统(acute physiological and chronic health evaluation-Ⅱ,APACHE-Ⅱ)在评估急诊内科患者病情的效果。方法 2014年1-3月,采用方便抽样法选取...目的比较改良早期预警评分(modified early warning score,MEWS)与急性生理和慢性健康评分系统(acute physiological and chronic health evaluation-Ⅱ,APACHE-Ⅱ)在评估急诊内科患者病情的效果。方法 2014年1-3月,采用方便抽样法选取乌鲁木齐市某三级甲等综合医院急诊内科患者640例为研究对象,对其进行MEWS评分以及入院24h后APACHE-Ⅱ评分,比较两种评分病情评估预测指标灵敏度、特异度、阳性预测值、阴性预测值、受试者ROC曲线。结果MEWS评分与APACHE-Ⅱ评分病情评估预测价值中等,MEWS评分ROC曲线下面积为0.648,最佳截断值是4分,灵敏度0.567,特异度0.708,阳性预测值71.68%,阴性预测值55.38%;APACHE-Ⅱ评分ROC曲线下面积为0.680,最佳截断值是14分,灵敏度61.16%,特异度66.79%,阳性预测值61.16%,阴性预测值66.79%;两种评分ROC曲线下面积比较,差异无统计学意义(P>0.05)。结论 MEWS评分可用于评估少数民族地区急诊内科患者病情,其操作简单便捷,可实现对患者病情的快速、动态监测,可与APACHE-Ⅱ评分进行联合应用。展开更多
文摘BACKGROUND: It has been suggested that addition of obesity score to the APACHE-Ⅱ system can lead to more accurate prediction of severity of acute pancreatitis. However there is scanty information on the usefulness of the combined APACHE-O scoring system in Asian patients. This study aimed to compare the accuracy of Ranson, APACHE-Ⅱ and APACHE-O systems in assessing severity of acute pancreatitis in a local Chinese population. METHODS: One hundred and one consecutive patients with acute pancreatitis were prospectively studied. Body mass index (BMI) was measured on admission. Ranson score, APACHE-Ⅱ and APACHE-O scores were recorded on admission and at 48 hours. By adopting the cut-off levels and definitions advocated in the Atlanta consensus for severe disease, the diagnostic accuracy of the three scoring systems was compared by the area under the curve (AUC) under the receiver operator characteristic curve. RESULTS: Of the 101 patients, 12 (11.9%) patients suffered from severe pancreatitis. Obesity was uncommon and only two patients (2.0%) had BMI >30. Eighty-two (81.2%) patients were normal weight (BMI≤25) whereas 17 (16.8%) were overweight ( BMI 25-30 ). Overweight or obesity (BMI >25) was not associated with severe pancreatitis (P= 0.40). The AUC for admission scores of Ranson, APACHE-Ⅱ, and APACHE-O systems was 0. 549, 0. 904 and 0. 904, respectively. The AUC for 48-hour scores of Ranson, APACHE-Ⅱ and APACHE-O systems was 0.808, 0.955 and 0.951, respectively. CONCLUSIONS: The APACHE-Ⅱ scoring system is more accurate than the Ranson scoring system of the prediction of severity in acute pancreatitis. Addition of obesity score does not significantly improve the predictive accuracy of the APACHE-Ⅱ system in our local population with a low prevalence of obesity.
文摘目的比较改良早期预警评分(modified early warning score,MEWS)与急性生理和慢性健康评分系统(acute physiological and chronic health evaluation-Ⅱ,APACHE-Ⅱ)在评估急诊内科患者病情的效果。方法 2014年1-3月,采用方便抽样法选取乌鲁木齐市某三级甲等综合医院急诊内科患者640例为研究对象,对其进行MEWS评分以及入院24h后APACHE-Ⅱ评分,比较两种评分病情评估预测指标灵敏度、特异度、阳性预测值、阴性预测值、受试者ROC曲线。结果MEWS评分与APACHE-Ⅱ评分病情评估预测价值中等,MEWS评分ROC曲线下面积为0.648,最佳截断值是4分,灵敏度0.567,特异度0.708,阳性预测值71.68%,阴性预测值55.38%;APACHE-Ⅱ评分ROC曲线下面积为0.680,最佳截断值是14分,灵敏度61.16%,特异度66.79%,阳性预测值61.16%,阴性预测值66.79%;两种评分ROC曲线下面积比较,差异无统计学意义(P>0.05)。结论 MEWS评分可用于评估少数民族地区急诊内科患者病情,其操作简单便捷,可实现对患者病情的快速、动态监测,可与APACHE-Ⅱ评分进行联合应用。
