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Preoperative, intraoperative and postoperative risk factors for anastomotic leakage after laparoscopic low anterior resection with double stapling technique anastomosis 被引量:54
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作者 Kenji Kawada Yoshiharu Sakai 《World Journal of Gastroenterology》 SCIE CAS 2016年第25期5718-5727,共10页
Anastomotic leakage(AL) is one of the most devastating complications after rectal cancer surgery. The double stapling technique has greatly facilitated intestinal reconstruction especially for anastomosis after low an... Anastomotic leakage(AL) is one of the most devastating complications after rectal cancer surgery. The double stapling technique has greatly facilitated intestinal reconstruction especially for anastomosis after low anterior resection(LAR). Risk factor analyses for AL after open LAR have been widely reported. However, a few studies have analyzed the risk factors for AL after laparoscopic LAR. Laparoscopic rectal surgery provides an excellent operative field in a narrow pelvic space, and enables total mesorectal excision surgery and preservation of the autonomic nervous system with greater precision. However, rectal transection using a laparoscopic linear stapler is relatively difficult compared with open surgery because of the width and limited performance of the linear stapler. Moreover, laparoscopic LAR exhibits a different postoperative course compared with open LAR, which suggests that the risk factors for AL after laparoscopic LAR may also differ from those after open LAR. In this review, we will discuss the risk factors for AL after laparoscopic LAR. 展开更多
关键词 Risk factor LAPAROSCOPIC low anterior resection Anastomotic leakage
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颅脑损伤后血清垂体前叶激素甲状腺素水平的变化及意义 被引量:51
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作者 龚德生 孔云龙 +2 位作者 邵耐远 刘信基 李璐 《中华创伤杂志》 CAS CSCD 北大核心 2000年第1期32-34,共3页
目的 研究颅脑损伤后下丘脑、垂体、甲状腺功能改变及意义。 方法 应用磁性酶联免疫定量分析法检测156 例急性颅脑损伤患者血清泌乳素(PRL) 、促卵泡生成素(FSH)、促甲状腺激素(TSH)、甲状腺素(T3 和T4) 水... 目的 研究颅脑损伤后下丘脑、垂体、甲状腺功能改变及意义。 方法 应用磁性酶联免疫定量分析法检测156 例急性颅脑损伤患者血清泌乳素(PRL) 、促卵泡生成素(FSH)、促甲状腺激素(TSH)、甲状腺素(T3 和T4) 水平的变化,并与100 例正常对照组比较。 结果 颅脑损伤急性期血清PRL、FSH、T4 含量显著升高,而T3 显著降低;分组资料表明,颅脑损伤愈严重,昏迷愈深,上述指标变化愈明显。部分病例受伤72 h 后及2 周后复测,上述指标逐渐恢复正常。结论 颅脑损伤急性期内分泌功能有明显异常变化。 展开更多
关键词 颅脑损伤 血清 垂体前叶激素 甲状腺素
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Anterior muscle sparing approach for total hip arthroplasty 被引量:47
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作者 Joseph T Moskal Susan G Capps John A Scanelli 《World Journal of Orthopedics》 2013年第1期12-18,共7页
The purpose of this review is to examine the validity of positive claims regarding the direct anterior approach(DAA) with a fracture table for total hip arthroplasty. Recent literature regarding the DAA was searched a... The purpose of this review is to examine the validity of positive claims regarding the direct anterior approach(DAA) with a fracture table for total hip arthroplasty. Recent literature regarding the DAA was searched and specific claims investigated including improved early outcomes, speed of recovery, component placement, dislocation rates, and complication rates. Recent literature is positive regarding the effects of total hip arthroplasty with the anterior approach. While the data is not definitive at present, patients receiving the anterior approach for total hip arthroplasty tend to recover more quickly and have improved early outcomes. Component placement with the anterior approach is more often in the "safe zone" than with other approaches. Dislocation rates tend to be less than 1% with the anterior approach. Complication rates vary widely in the published literature. A possible explanation is that the varianceis due to surgeon and institutional experience with the anterior approach procedure. Concerns remain regarding the "learning curve" for both surgeons and institutions. In conclusion, it is not a matter of should this approach be used, but how should it be implemented. 展开更多
关键词 Total HIP ARTHROPLASTY anterior APPROACH HIP ARTHRITIS Joint replacement
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前壁急性ST段抬高型心肌梗死患者直接经皮冠状动脉介入术后主要不良心血管事件发生的影响因素 被引量:43
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作者 刘雅婷 谷新顺 +1 位作者 张芳 赵甲彧 《中华实用诊断与治疗杂志》 2020年第5期505-508,共4页
目的探讨前壁急性ST段抬高型心肌梗死(ST-elevation myocardial infarction,STEMI)患者直接经皮冠状动脉介入术(percutaneous coronary intervention,PCI)后发生主要不良心血管事件(major adverse cardiovascular events,MACE)的影响因... 目的探讨前壁急性ST段抬高型心肌梗死(ST-elevation myocardial infarction,STEMI)患者直接经皮冠状动脉介入术(percutaneous coronary intervention,PCI)后发生主要不良心血管事件(major adverse cardiovascular events,MACE)的影响因素。方法前壁STEMI患者92例,均行直接PCI治疗,术后12~24h行心肌超声造影测量心肌血管床容积(A)、心肌血流速度(β)、心肌血流量(A×β)及左室射血分数。PCI后随访6个月,13例发生MACE者为MACE组,79例未发生MACE者为无MACE组。比较2组临床资料、生化指标、PCI治疗相关资料,多因素logistic回归分析前壁STEMI患者PCI后发生MACE的影响因素。结果MACE组PCI前血清B型脑钠肽[(413.00±101.72)ng/L]、PCI次日肌钙蛋白I峰值[(66.20±17.89)μg/L]较无MACE组[(295.80±155.77)ng/L、(42.68±22.73)μg/L]高(P<0.05)。2组年龄,男性比率,吸烟比率,有高血压、糖尿病、冠心病家族史比率以及PCI次日血清总胆固醇、三酰甘油、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇水平比较差异无统计学意义(P>0.05)。MACE组A[(6.39±0.75)dB]、β[(0.45±0.06)/s]、A×β[(2.82±0.51)dB/s]、左室射血分数[(45.00±2.92)%]较无MACE组[(7.38±0.76)dB、(0.51±0.07)/s、(3.79±0.72)dB/s、(50.90±6.00)%]低(P<0.05)。MACE组PCI后心肌灌注分级3级比率(46.15%)较无MACE组(69.62%)低,发病至再灌注时间[(368.26±60.35)min]较无MACE组[(293.23±99.63)min]长(P<0.05)。多因素logistic回归分析结果显示,A×β(OR=0.047,95%CI:0.003~0.729,P=0.029)、肌钙蛋白I峰值(OR=1.069,95%CI:1.001~1.141,P=0.047)是前壁STEMI患者PCI后6个月发生MACE的影响因素。结论前壁STEMI患者PCI后6个月发生MACE与PCI次日肌钙蛋白I峰值及心肌血流量有关。 展开更多
关键词 急性ST段抬高型心肌梗死 前壁 直接经皮冠状动脉介入术 主要不良心血管事件 心肌超声造影
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Neoadjuvant radiotherapy for rectal cancer management 被引量:36
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作者 Gerard Feeney Rishabh Sehgal +4 位作者 Margaret Sheehan Aisling Hogan Mark Regan Myles Joyce Michael Kerin 《World Journal of Gastroenterology》 SCIE CAS 2019年第33期4850-4869,共20页
Thirty per cent of all colorectal tumours develop in the rectum.The location of the rectum within the bony pelvis and its proximity to vital structures presents significant therapeutic challenges when considering neoa... Thirty per cent of all colorectal tumours develop in the rectum.The location of the rectum within the bony pelvis and its proximity to vital structures presents significant therapeutic challenges when considering neoadjuvant options and surgical interventions.Most patients with early rectal cancer can be adequately managed by surgery alone.However,a significant proportion of patients with rectal cancer present with locally advanced disease and will potentially benefit from down staging prior to surgery.Neoadjuvant therapy involves a variety of options including radiotherapy,chemotherapy used alone or in combination.Neoadjuvant radiotherapy in rectal cancer has been shown to be effective in reducing tumour burden in advance of curative surgery.The gold standard surgical rectal cancer management aims to achieve surgical removal of the tumour and all draining lymph nodes,within an intact mesorectal package,in order to minimise local recurrence.It is critically important that all rectal cancer cases are discussed at a multidisciplinary meeting represented by all relevant specialties.Pre-operative staging including CT thorax,abdomen,pelvis to assess for distal disease and magnetic resonance imaging to assess local involvement is essential.Staging radiology and MDT discussion are integral in identifying patients who require neoadjuvant radiotherapy.While Neoadjuvant radiotherapy is potentially beneficial it may also result in morbidity and thus should be reserved for those patients who are at a high risk of local failure,which includes patients with nodal involvement,extramural venous invasion and threatened circumferential margin.The aim of this review is to discuss the role of neoadjuvant radiotherapy in the management of rectal cancer. 展开更多
关键词 RECTAL cancer NEOADJUVANT therapy Low anterior resection syndrome STOMA TRANSANAL endoscopic MICROSURGERY Trans-anal total mesorectal EXCISION Robotic surgery Watch and wait
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Direct anterior total hip arthroplasty: Literature review of variations in surgical technique 被引量:33
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作者 Keith P Connolly Atul F Kamath 《World Journal of Orthopedics》 2016年第1期38-43,共6页
The direct anterior approach to the hip has been suggested to have several advantages compared to previously popular approaches through its use of an intra-muscular and intra-nervous interval betweenthe tensor fasciae... The direct anterior approach to the hip has been suggested to have several advantages compared to previously popular approaches through its use of an intra-muscular and intra-nervous interval betweenthe tensor fasciae latae and sartorius muscles. Recent increased interest in tissue-sparing and minimallyinvasive arthroplasty has given rise to a sharp increase in the utilization of direct anterior total hip arthroplasty. A number of variations of the procedure have been described and several authors have published their experiences and feedback to successfully accomplishing this procedure. Additionally, improved understanding of relevant soft tissue constraints and anatomic variants has provided improved margin of safety for patients. The procedure may be performed using speciallydesigned instruments and a fracture table, however many authors have also described equally efficacious performance using a regular table and standard arthroplasty tools. The capacity to utilize fluoroscopy intraoperatively for component positioning is a valuable asset to the approach and can be of particular benefit for surgeons gaining familiarity. Proper management of patient and limb positioning are vital to reducing risk of intra-operative complications. An understanding of its limitations and challenges are also critical to safe employment. This review summarizes the key features of the direct anterior approach for total hip arthroplasty as an aid to improving the understanding of this important and effective method for modern hip replacement surgeons. 展开更多
关键词 anterior HIP ARTHROPLASTY anterior SUPINE intramuscular APPROACH Total HIP ARTHROPLASTY DIRECT anterior APPROACH
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Relationship between tunnel widening and different rehabilitation procedures after anterior cruciate ligament reconstruction with quadrupled hamstring tendons 被引量:27
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作者 YUJia-kuo HansH.Paessler 《Chinese Medical Journal》 SCIE CAS CSCD 2005年第4期320-326,共7页
Background It has been demonstrated that bone tunnel widening could appear after knee anterior cruciate ligament (ACL) reconstruction, especially for those patients whose ruptured ACL were reconstructed with semitendi... Background It has been demonstrated that bone tunnel widening could appear after knee anterior cruciate ligament (ACL) reconstruction, especially for those patients whose ruptured ACL were reconstructed with semitendinosus and gracilis tendons. Many factors can influence the extent of tunnel widening. Few studies have investigated the relationship between bone tunnel widening and rehabilitation procedures. This research was carried out to find the rehabilitation procedures' influence on the tibial bone tunnel widening after ACL reconstruction. Methods Sixty-five cases, whose ACL reconstructions were done using quadrupled semitendinosus and gracilis tendons, were divided into two groups. Group A had 33 cases, 19 men, 14 women, averaged (31.2±12.4) years old, only ACL reconstruction was done using Paessler's technique, and aggressive rehabilitation procedure was used for function recovery post operation. Group B had 32 cases, 20 men, 12 women, averaged (30.3±10.3) years old. Except for ACL reconstruction, every patient in group B accepted meniscus repair using re-fixation methods or cartilage repair using microfracture technique, conservative rehabilitation procedure was used post operation. Six months post operation, standard posterior-anterior radiographic plates were taken for each case, CorelDRAW 8.0 software was used to digitize all X-ray plates and measure the upper, middle and lower parts of the tibial tunnel. Magnification effect of X-ray plates was taken out after measurement. Results Six months after ACL reconstruction the tibial tunnel widening of the upper, middle and lower parts on both the posterior-anterior and lateral X-ray plates in Group A with aggressive rehabilitation procedure was much more serious than in Group B with conservative rehabilitation. KT-1000 knee stability measurement and clinical manifestation showed no difference between the two groups. Conclusions Rehabilitation procedure after ACL reconstruction is one of the reasons for tunnel widening. It not only can directly influence th 展开更多
关键词 semitendinosus tendon gracilis tendon anterior cruciate ligament tunnel widening
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Anterior resection for rectal carcinoma-risk factors for anastomotic leaks and strictures 被引量:29
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作者 Ashok Kumar Ram Daga +5 位作者 Paari Vijayaragavan Anand Prakash Rajneesh Kumar Singh Anu Behari Vinay K Kapoor Rajan Saxena 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第11期1475-1479,共5页
AIM:To determine the incidence and factors responsible for anastomotic leaks and stricture following anterior resection(AR)and its subsequent management.METHODS:Retrospective analysis of data from 108 patients with re... AIM:To determine the incidence and factors responsible for anastomotic leaks and stricture following anterior resection(AR)and its subsequent management.METHODS:Retrospective analysis of data from 108 patients with rectal carcinoma who underwent AR or low anterior resection(LAR)to identify the various preoperative,operative,and post operative factors that might have influence on anastomotic leaks and strictures.RESULTS:There were 68 males and 40 females with an average of 47 years(range 21-75 years).The median distance of the tumor from the anal verge was 8 cm(range 3-15 cm).Sixty(55.6%)patients underwent handsewn anastomosis and 48(44.4%)were stapled.The median operating time was 3.5 h(range2.0-7.5 h).Sixteen(14.6%)patients had an anastomotic leak.Among these,11 patients required reexploration and five were managed expectantly.The anastomotic leak rate was similar in patients with and without diverting stoma(8/60,13.4%with stoma and 8/48;16.7%without stoma).In 15(13.9%)patients,resection margins were positive for malignancy.Ninteen(17.6%)patients developed anastomotic strictures at a median duration of 8 mo(range 3-20 mo).Among these,15 patients were successfully managed with per-anal dilatation.On multivariate analysis,advance age(>60 years)was the only risk factor for anastomotic leak(P=0.004).On the other hand,anastomotic leak(P=0.00),mucin positive tumor(P =0.021),and lower rectal growth(P=0.011)were found as risk factors for the development of an anastomotic stricture.CONCLUSION:Advance age is a risk factor for an anastomotic leak.An anastomotic leak,a mucin-secreting tumor,and lower rectal growth predispose patients to develop anastomotic strictures. 展开更多
关键词 Rectal carcinoma anterior resection Anastomotic leak STRICTURE
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急性前壁ST段抬高心肌梗死患者的心电图表现及心肌酶峰与近期左心功能的相关性 被引量:29
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作者 孙王乐贤 赵洁 +5 位作者 刘会玲 单伟超 张英 郭金锐 孙静 李春华 《中华医学杂志》 CAS CSCD 北大核心 2014年第3期187-190,共4页
目的探讨急性前壁ST段抬高心肌梗死(STEMI)患者的心电图及心肌酶峰与左室功能的相关性。方法2009年1月至2012年1月河北承德医学院附属医院心内科住院STEMI患者288例,其中前壁186例,符合纳入标准的138例均连续人选,收集患者的临床... 目的探讨急性前壁ST段抬高心肌梗死(STEMI)患者的心电图及心肌酶峰与左室功能的相关性。方法2009年1月至2012年1月河北承德医学院附属医院心内科住院STEMI患者288例,其中前壁186例,符合纳入标准的138例均连续人选,收集患者的临床资料并随访梗死后3个月心功能。结果STEMI患者的心电图前壁导联ST段抬高幅度之和(∑ST)、Q波之和(∑Q)以及Q波导联数,与Killip分级、心肌酶峰值、脑钠肽(BNP)、急性期/梗死后3个月的左室舒张末内径(LVEDD)正相关[γ,0.52~0.75,P〈0.01],但与急性期/梗死后3个月的左室射血分数(LVEF)负相关[γ,-0.63~-0.95,P〈0.01];前壁导联R波振幅之和(∑R),与心肌酶峰值、BNP、急性期/梗死后3个月LVEDD负相关[γ,-0.48~-0.79,P〈0.01],但与急性期/梗死后3个月LVEF正相关[γ,0.73~0.82,P〈0.01];前壁各导联ST段抬高最大值,与Killip分级、心肌酶峰值、BNP、急性期/梗死后3个月LVEDD正相关[γ,0.41~0.62,P〈0.05]。Q波振幅最大值,与Killip分级、心肌酶峰值、BNP、急性期/梗死后3个月的LVEDD正相关[γ,0.42~0.64,P〈0.05]。∑ST、∑Q、∑R和Q波导联数与梗死后3个月心功能无显著相关(P〉0.05)。BNP与STEMI急性期/3个月LVEF呈强负相关[γ,-0.92、-0.80,P〈0.01]。结论急性前壁STEMI心电图ST段、Q波、R波及心肌酶峰与左室功能呈强相关,可用于预测STEMI后近期心功能。 展开更多
关键词 急性心肌梗死 前壁 心电图 心肌酶 左心功能
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内镜经鼻前颅底肿瘤的外科治疗 被引量:26
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作者 孔锋 张秋航 严波 《中国微侵袭神经外科杂志》 CAS 2006年第10期443-445,共3页
目的总结内镜经鼻入路切除前颅底肿瘤的经验。方法回顾性分析2003年11月~2006年5月18例肿瘤侵犯前颅底的临床资料,其中14例单独采用内镜经鼻手术入路,4例采用颅鼻联合入路进行了治疗。病理类型包括:脑膜瘤2例,脊索瘤1例,视神经鞘瘤1例... 目的总结内镜经鼻入路切除前颅底肿瘤的经验。方法回顾性分析2003年11月~2006年5月18例肿瘤侵犯前颅底的临床资料,其中14例单独采用内镜经鼻手术入路,4例采用颅鼻联合入路进行了治疗。病理类型包括:脑膜瘤2例,脊索瘤1例,视神经鞘瘤1例,骨纤维异常增殖症1例,鳞状细胞癌3例,嗅神经母细胞瘤3例,腺样囊性癌1例,恶性骨巨细胞瘤1例,脊索肉瘤1例,神经内分泌小细胞癌1例,透明细胞癌1例,甲状腺癌颅底转移1例,腮腺癌颅底转移1例。结果经术中镜下及术后影像学检查证实17例肿瘤被全部切除,1例大部分切除。2例术后出现脑脊液鼻漏,经保守治疗后痊愈。无颅内出血、感染及死亡病例。结论内镜经鼻入路能够充分显露和切除前颅底肿瘤,且大多数病例无需处理硬脑膜及进行颅底重建。 展开更多
关键词 内镜外科 颅窝 肿瘤
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心电图以ST段抬高为特征的TakoSTubo心肌病与急性前壁ST段抬高型心肌梗死临床特征比较 被引量:28
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作者 梁滨 黄榕翀 +5 位作者 康美丽 史晓利 李智 刘俊 朱皓 周旭晨 《中国循环杂志》 CSCD 北大核心 2015年第6期534-539,共6页
目的:分析单中心急性心肌梗死患者6年临床数据,探讨Tako STubo心肌病患者与急性心肌梗死患者临床特征的差异。方法:连续入选2008-01至2014-04在大连医科大学附属第一医院心内科住院,初步诊断为急性前壁ST段抬高型心肌梗死患者1 042例。... 目的:分析单中心急性心肌梗死患者6年临床数据,探讨Tako STubo心肌病患者与急性心肌梗死患者临床特征的差异。方法:连续入选2008-01至2014-04在大连医科大学附属第一医院心内科住院,初步诊断为急性前壁ST段抬高型心肌梗死患者1 042例。经冠状动脉造影和左心室造影更正诊断为Tako STubo心肌病有10例患者纳入Tako STubo心肌病组。选取同一时期内发病时间≤6 h,诊断为急性前壁ST段抬高型心肌梗死,经冠状动脉造影证实为前降支单支病变的32例患者纳入前壁急性心肌梗死组。比较两组患者的基本临床特征、血脂水平、心肌标志物水平、常规12导联心电图前壁导联病理性Q波发生率、QTc间期及倒置T波分布情况。结果:在初步诊断为急性前壁ST段抬高型心肌梗死患者中,修正诊断为Tako STubo心肌病的比例为1.06%。Tako STubo心肌病组患者均为女性患者,前壁急性心肌梗死组患者中女性占9%(P<0.01)。Tako STubo心肌病组发病前存在应激史的患者比例显著高于前壁急性心肌梗死组(70%vs 22%,P=0.02),Tako STubo心肌病组患者心肌标志物峰值水平显著低于前壁急性心肌梗死组[肌酸激酶:(486.0±249.0)U/L vs(716.0±132.0)U/L,肌酸激酶同工酶:(13.5±17.1)mg/L vs(47.5±21.9)mg/L,心肌肌钙蛋白I:(22.8±16.3)ng/ml vs(56.4±24.0)ng/ml,P均<0.01]。两组间发病年龄、高血压患者比例、糖尿病患者比例、血脂水平差异均无统计学意义。两组间前壁导联Q波发生率差异无统计学意义;但Tako STubo心肌病组与前壁急性心肌梗死组在QTc间期[(630.0±117.0)ms vs(540.0±62.0)ms,P=0.001]、12导联心电图Ⅱ、Ⅲ、a VF、a VR、V6导联倒置T波发生率的差异有统计学意义(分别为100.00%vs 3.13%;60.00%vs 6.25%;90.00%vs 3.13%;100.00%vs 21.88%;100.00%vs 46.88%;P均<0.05)。结论:与急性前壁ST段抬高型心肌梗死患者相比,心电图以ST段抬高为特征的Tako STubo心肌病患者发病前多伴精神� 展开更多
关键词 TakoSTubo心肌病 急性心肌梗死 前壁 心电图
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前、后路内固定融合术治疗脊柱胸腰段骨折的比较研究 被引量:27
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作者 洪全明 杨可佳 +3 位作者 沈飞 孙春华 严家生 季一明 《创伤外科杂志》 2016年第12期708-712,共5页
目的探讨比较脊柱前、后路内固定融合术治疗胸腰段骨折的临床疗效。方法笔者对2011年1月~2013年12月收治的90例胸腰段骨折患者的临床治疗及随访资料进行回顾性分析,按照手术方式采用前路内固定融合治疗(42例)和后路内固定融合术治疗... 目的探讨比较脊柱前、后路内固定融合术治疗胸腰段骨折的临床疗效。方法笔者对2011年1月~2013年12月收治的90例胸腰段骨折患者的临床治疗及随访资料进行回顾性分析,按照手术方式采用前路内固定融合治疗(42例)和后路内固定融合术治疗(48例),统计分析两组患者的术中情况、术后不同时间的X线评价指标、美国脊柱损伤协会(ASIA)神经功能恢复及临床疗效差异。结果后路组的手术时间(147.3±38.7)min、术中出血量(607.5±162.3)m L、手术切口长度(10.3±1.8)cm、术后住院时间(10.6±2.0)d均显著低于前路组患者(P〈0.05)。术前、术后即刻两组患者的前缘高度比值、Cobb角测量值差异均不具有统计学意义(P〉0.05)。术后末次随访,后路组术后即刻伤椎前缘高度丢失(1.55±0.17)mm、Cobb角丢失(1.26±0.72)°,均显著低于前路组(7.18±1.51)mm、(7.43±1.85)°。术前、术后后路组和前路组ASIA分布差异不显著(P〉0.05);术后两组ASIA神经功能恢复分布较术前均显著好转(P〈0.05)。末次随访时,后路组患者的Oswestry功能障碍指数(ODI)优级率(77.08%)高于前路组(52.38%),良和差均显著低于前路组患者,后路组的ODI功能分布显著优于前路组(P〈0.05)。结论脊柱后路内固定融合术治疗胸腰段骨折较前路术创伤小、术后恢复快、Cobb角度丢失小,临床疗效更加可靠。 展开更多
关键词 胸腰段骨折 脊柱 内固定 融合术 前路 后路
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Laparoscopic low anterior resection for rectal carcinoma:Complications and management in 132 consecutive patients 被引量:24
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作者 Qian-Lin Zhu,Bo Feng,Ai-Guo Lu,Ming-Liang Wang,Wei-Guo Hu,Jian-Wen Li,Zhi-Hai Mao,Min-Hua Zheng,Department of General Surgery,Shanghai Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China Shanghai Minimally Invasive Surgery Center,Shanghai 200025,China 《World Journal of Gastroenterology》 SCIE CAS CSCD 2010年第36期4605-4610,共6页
AIM:To analyze the clinical manifestations and risk fac-tors of complications in laparoscopic low anterior resection(LAR)for rectal cancer patients.METHODS:A series of 132 consecutive patients who received laparoscopi... AIM:To analyze the clinical manifestations and risk fac-tors of complications in laparoscopic low anterior resection(LAR)for rectal cancer patients.METHODS:A series of 132 consecutive patients who received laparoscopic LAR for rectal cancer in our center were included.The etiology,diagnosis,treatment and prevention of rectal cancer were studied among the patients with surgery-related complications using both univariate and multivariate regression analysis.RESULTS:No conversion to open surgery was observed and 5 cases converted to hand-assisted laparoscopic operation.The overall morbidity rate was 20.5%.Complications occurred during the operation in 7 patients(5.3%),within 30 postoperative days in 24 patients(18.2%),and within 3 mo in 2 patients(1.5%).The most significant complications were anastomotic leak-age(9.1%)and anastomotic hemorrhage(5.3%).Sizeand location of tumor,pathological staging and preoperative nutrition were significant factors associated with LAR complications,while gender,age and pathological type showed no relevance.Binary logistics regression showed that the size and location of tumor,and pathological staging were independent factors of laparoscopic LAR.All the complications were treated during their onset of clinical manifestations by interventional or conservative therapy.CONCLUSION:Anastomotic leakage is a major com-plication in laparoscopic LAR.The complications may be associated with tumor size and site,and pathological stage.Interventional therapies are of value in the management of laparoscopic LAR complications. 展开更多
关键词 LAPAROSCOPY Low anterior RESECTION COMPLICATION RECTAL cancer Logistic regression analysis
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Factors affecting proprioceptive recovery after anterior cruciate ligament reconstruction 被引量:22
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作者 ZHOU Mou-wang GU Li +4 位作者 CHEN Ya-ping YU Chang-long AO Ying-fang HUANG Hong-shi YANG Yan-yan 《Chinese Medical Journal》 SCIE CAS CSCD 2008年第22期2224-2228,共5页
Background Proprioception plays an important role in knee movements. Since there are controversies surrounding the overall recovery time of proprioception following surgery, it is necessary to define the factors affec... Background Proprioception plays an important role in knee movements. Since there are controversies surrounding the overall recovery time of proprioception following surgery, it is necessary to define the factors affecting proprioceptive recovery after anterior cruciate ligament (ACL) reconstruction and to investigate the relationship between proprioception and muscle strength. Methods A total of 36 patients who had their ACL reconstructed with a semitendinosus/gracilis graft (reconstructed group: 6 months post-surgery) and 13 healthy adults without any knee injury (control group) were included in the study. Knee proprioception was evaluated with a passive reproduction test. Isokinetic strength was measured using the Biodex System. Statistical analysis was used to compare proprioception of the reconstructed group versus the control group, and to define causal factors, including sex, hamstring/quadriceps ratio, and the course of injury before reconstruction, We also investigated the correlation between the passive reproduction error and quadriceps index. Results There was a significant difference in proprioception between the reconstructed and control groups (P 〈0.05). When the course of injury before reconstruction was less than 4 months, there was a linear correlation with proprioception 6 months after the operation (r=0.713, P 〈0.05). There was a positive correlation between post-surgery proprioception and the quadriceps index at 6 months post-surgery. Conclusions Impaired knee proprioception is observed 6 months after ACL reconstruction. Within 4 months of injury, early undertaking of reconstruction is associated with better proprioception outcome. Patients with enhanced proprioception have a better quadriceps index. 展开更多
关键词 anterior cruciate ligament reconstruction proprioception muscle strength
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胸腰椎脊柱结核的手术治疗方式选择及疗效评价 被引量:23
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作者 周纲 黄卫民 +2 位作者 田慧中 胡永胜 张玉堃 《中国矫形外科杂志》 CAS CSCD 北大核心 2016年第15期1363-1367,共5页
[目的]比较前路和后路两种病灶清除植骨内固定术对胸腰椎脊柱结核清除结核病灶、脊髓神经减压及重建脊柱稳定性的疗效。[方法]随机抽取2008年10月~2014年2月手术治疗的胸、腰椎脊柱结核69例进行回顾性分析,根据手术方式分为前路手术组... [目的]比较前路和后路两种病灶清除植骨内固定术对胸腰椎脊柱结核清除结核病灶、脊髓神经减压及重建脊柱稳定性的疗效。[方法]随机抽取2008年10月~2014年2月手术治疗的胸、腰椎脊柱结核69例进行回顾性分析,根据手术方式分为前路手术组(前路组)31例和后路手术组(后路组)38例,比较两组患者住院时间、手术时间、术中出血量、疼痛视觉模拟评分(visual analog scale,VAS)及功能障碍评分(Oswestry disability index,ODI)降低值、满意度的差异。[结果]后路组患者ODI评分术后降低值大于前路组,虽差异无统计学意义,但P值为0.54;后路组患者手术时间、术中出血量及住院时间均少于前路组,均P〈0.05。[结论]前路和后路病灶清除植骨内固定术对胸腰椎脊柱结核均有较好的治疗效果,相比而言前路手术组创伤较大,后路手术具有一定的优势。 展开更多
关键词 胸腰椎结核 前路手术 后路手术
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Can trans-anal reinforcing sutures after double stapling in lower anterior resection reduce the need for a temporary diverting ostomy? 被引量:20
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作者 Se-Jin Baek Jin Kim +1 位作者 Jungmyun Kwak Seon-Hahn Kim 《World Journal of Gastroenterology》 SCIE CAS 2013年第32期5309-5313,共5页
AIM:To evaluate trans-anal reinforcing sutures in low anterior resection using the double-stapled anastomosis technique for primary rectal cancers performed at a single institution.METHODS:The data of patients who rec... AIM:To evaluate trans-anal reinforcing sutures in low anterior resection using the double-stapled anastomosis technique for primary rectal cancers performed at a single institution.METHODS:The data of patients who received transanal reinforcing sutures were compared with those of patients who did not receive them after low anterior resection.Patients who underwent laparoscopic low anterior resection and the double-stapled anastomosis technique for primary rectal cancer between January2008 and December 2011 were included in this study.Patients with no anastomosis,a hand-sewn anastomosis,high anterior resection,or preoperative chemoradiation were excluded.The primary outcomes measured were the incidence of postoperative anastomotic complications and placement of a diverting ileostomy.RESULTS:Among 110 patients,the rate of placement of a diverting ileostomy was significantly lower in the suture group(SG)compared with the non-suture control group(CG)[SG,n=6(12.8%);CG,n=19(30.2%),P=0.031].No significant difference was observed in the rate of anastomotic leakage[SG,n=3(6.4%);CG,n=5(7.9%)].CONCLUSION:Trans-anal reinforcing sutures may reduce the need for diverting ileostomy.A randomized prospective study with a larger population should be performed in the future to demonstrate the efficacy of trans-anal reinforcing sutures. 展开更多
关键词 Anastomotic leak Low anterior resection RECTAL neoplasms Double-stapled anastomotic technique Reinforcement SUTURES
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两种手术入路治疗胸腰段脊柱骨折伴脊髓损伤的研究 被引量:21
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作者 邓险峰 张文 《西南国防医药》 CAS 2015年第4期402-404,共3页
目的 比较前路与后路手术入路在解除脊髓受压、恢复脊髓稳定性等方面的治疗效果。方法 回顾性分析我院2010年2月~2013年8月收治的120例胸腰段脊柱骨折合并脊髓损伤患者的临床资料,随机分为观察组与对照组,其中观察组60例采用前路手术入... 目的 比较前路与后路手术入路在解除脊髓受压、恢复脊髓稳定性等方面的治疗效果。方法 回顾性分析我院2010年2月~2013年8月收治的120例胸腰段脊柱骨折合并脊髓损伤患者的临床资料,随机分为观察组与对照组,其中观察组60例采用前路手术入路法,对照组60例采用后路手术入路方法,比较两组的手术效果。结果 对照组的术中出血量少于观察组,且手术时间短于观察组(P〈0.05),但是观察组的术后触觉评分、运动评分、Cobb角、伤椎高度等指标均较对照组改善更明显(P〈0.05)。结论 采用前路手术入路方法治疗胸腰段脊柱骨折合并脊髓损伤,可有效恢复和改善患者的脊髓功能,明显提高患者的脊柱稳定性,有利于患者的早期功能恢复,从而提高患者的生活质量,改善患者的预后。 展开更多
关键词 前路 后路 手术入路 胸腰段 脊柱 骨折
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Transanal natural orifice specimen extraction for laparoscopic anterior resection in rectal cancer 被引量:19
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作者 Fang-Hai Han Li-Xin Hua +2 位作者 Zhi Zhao Jian-Hai Wu Wen-Hua Zhan 《World Journal of Gastroenterology》 SCIE CAS 2013年第43期7751-7757,共7页
AIM: To investigate whether transanal natural orifice specimen extraction (NOSE) is a better technique for rectal cancer resection.METHODS: A prospectively designed database of a consecutive series of patients undergo... AIM: To investigate whether transanal natural orifice specimen extraction (NOSE) is a better technique for rectal cancer resection.METHODS: A prospectively designed database of a consecutive series of patients undergoing laparoscopic low anterior resection for rectal cancer with various tumor-node-metastasis classi?cations from March 2011 to February 2012 at the First Affiliated Hospital of Sun Yat-Sen University was analyzed. Patient selection for transanal specimen extraction and intracorporeal anastomosis was made on the basis of tumor size and distance of rectal lesions from the anal verge. Demographic data, operative parameters, and postoperative outcomes were assessed.RESULTS: None of the patients was converted to laparotomy. Respectively, there were 16 cases in the low anastomosis and five in the ultralow anastomosis groups. Mean age of the patients was 45.4 years, and mean body mass index was 23.1 kg/m2. Mean distance of the lower edge of the lesion from the anal verge was 8.3 cm. Mean operating time was 132 min, and mean intraoperative blood loss was 84 mL. According to the principle of rectal cancer surgery, we performed D2 lymph node dissection in 13 cases and D3 in eight. Mean lymph nodes harvest was 17.8, and the number of positive lymph nodes was 3.4. Median hospital stay was 6.7 d. No serious postoperative complication occurred except for one anastomotic leakage. All patients remained disease free. Mean Wexner score was 3.7 at 11 mo after the operation.CONCLUSION: Transanal NOSE for total laparoscopic low/ultralow anterior resection is feasible, safe and oncologically sound. Further studies with long-term outcomes are needed to explore its potential advantages. 展开更多
关键词 Transanal specimen extraction Natural orifice specimen extraction Laparoscopic anterior resection Low/ultra-low anastomosis Total mesorectal excision
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前置与上置钢板内固定治疗锁骨中段骨折的生物力学对比分析 被引量:18
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作者 汤凌 《创伤外科杂志》 2016年第6期334-337,共4页
目的对比分析于不同位置重建钢板内固定治疗锁骨中段骨折的生物力学特性,为选择手术方案建立理论依据。方法选取上海交通大学医学院解剖教研室提供的新鲜成人尸体锁骨标本15具(共30根),随机选取10具(20根)用锯条切割制备锁骨中段粉碎性... 目的对比分析于不同位置重建钢板内固定治疗锁骨中段骨折的生物力学特性,为选择手术方案建立理论依据。方法选取上海交通大学医学院解剖教研室提供的新鲜成人尸体锁骨标本15具(共30根),随机选取10具(20根)用锯条切割制备锁骨中段粉碎性骨折标本。将骨折标本随机等分为钢板上置组和钢板前置组各5具(10根)。前组将重建钢板塑形后固定于锁骨上方,后组固定于锁骨前方,保证两组标本的骨折线两侧均固定有3枚螺钉;余下5具锁骨标本(10根)作为对照组,无任何干预措施。观察并比较三组标本的强度、弯曲刚度、扭转刚度等生物力学性质。结果在不同载荷下,三组模型的平均应变及位移差异均无统计学意义(P>0.05);三组标本的最大强度与弯曲刚度差异无统计学意义(P>0.05);三组标本的平均最大拉伸载荷由高到低依次为对照组[(1260±57)N]、钢板前置组[(1078±65)N]和钢板上置组[(989±62)N],钢板前置组的抗拉伸作用明显强于钢板上置组,差异有统计学意义(F=3.133,P=0.047);钢板前置组内固定的平均应力遮挡率[(18.73±2.98)%]明显低于钢板上置组[(27.52±3.24)%],差异有统计学意义(F=6.314,P=0.031)。结论对于锁骨中段粉碎性骨折,重建钢板内固定治疗效果明确。在钢板位置的选择上,前置的生物力学性质更加稳定,应作为临床首选方案。 展开更多
关键词 锁骨骨折 钢板 前置 上置 标本 生物力学
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前路减压植骨内固定治疗胸腰椎爆裂骨折的疗效分析 被引量:15
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作者 梁涛 刘浩 +4 位作者 龚全 丰干均 石锐 赵献峰 曾建成 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2010年第2期117-121,共5页
目的:探讨经前路减压植骨内固定治疗胸腰椎爆裂骨折的适应证和疗效。方法:2005年1月~2007年6月,应用前路减压、钛网植骨、单节段或双节段内固定治疗Denis分类不稳定的胸腰椎爆裂骨折患者43例,男28例,女15例,平均年龄37.3岁。骨折部位:T... 目的:探讨经前路减压植骨内固定治疗胸腰椎爆裂骨折的适应证和疗效。方法:2005年1月~2007年6月,应用前路减压、钛网植骨、单节段或双节段内固定治疗Denis分类不稳定的胸腰椎爆裂骨折患者43例,男28例,女15例,平均年龄37.3岁。骨折部位:T129例,L122例,L26例,T12合并L1、L51例,T12、L12例,L1、L23例。骨折Denis分类:A型21例,B型18例,E型4例。31例伴脊髓神经功能损害,Frankel分级A级4例,B级6例,C级8例,D级13例。经胸入路12例,经胸膜外腹膜后入路25例,经腹膜后入路6例;16例行单节段固定,27例行双节段固定。均采用Antares脊柱内固定系统固定,随访观察治疗效果。结果:所有患者顺利完成手术,单节段固定平均手术时间为150±70min,出血量平均428±85ml;双节段固定平均手术时间为260±78min,出血量平均830±126ml。胸腔引流时间3~5d,平均3.1d。伤口均一期愈合,3例合并肺部感染,治疗后均痊愈。单节段组融合节段平均后凸角5.2°±3.3°(2.1°~10.4°),平均矫正率为(63.9±1.4)%。双节段组融合节段平均后凸角4.9°±2.0°(2.5°~11.2°),平均矫正率为(66.2±2.2)%。术后随访6~28个月,平均16.4个月,无内固定失败,矫正度无明显丢失,均获得良好植骨融合。末次随访时16例患者神经功能有1级以上改善。结论:前路手术治疗不稳定性胸腰椎爆裂骨折减压彻底,使用Antares脊柱内固定系统操作简便、固定牢靠。 展开更多
关键词 胸腰椎 爆裂骨折 前入路 内固定
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