目的寻找一种更快速、简便的人类免疫缺陷病毒(HIV)感染的筛查方法。方法对门诊和住院手术患者标本以及疾病控制中心质控标本,采用VIDAS HIV DUO Ultra方法(简称VIDAS)测定HIV p24抗原和HIV抗体,并与第3代酶联免疫吸附试验(ELISA)以...目的寻找一种更快速、简便的人类免疫缺陷病毒(HIV)感染的筛查方法。方法对门诊和住院手术患者标本以及疾病控制中心质控标本,采用VIDAS HIV DUO Ultra方法(简称VIDAS)测定HIV p24抗原和HIV抗体,并与第3代酶联免疫吸附试验(ELISA)以及明胶粒子凝集法(PA)测定结果进行比较。结果对50份标本采用VIDAS进行检测,其敏感性和特异性分别为91.7%和92.1%。结论VIDAS可作为一种更简便的HIV检测方法,在生物安全控制方面较其他2种方法更安全有效。展开更多
This is a GATE-simulation study of the Siemens Biograph DUO PET/CT system. It reports effects of changes in the thickness of the employed Lutetium Oxyorthosilicate(LSO) detectors. The PET/CT, a human body phantom and ...This is a GATE-simulation study of the Siemens Biograph DUO PET/CT system. It reports effects of changes in the thickness of the employed Lutetium Oxyorthosilicate(LSO) detectors. The PET/CT, a human body phantom and a cylindrical F-18 FDG source were simulated. Validation measurements were conducted. The results indicate that LSO thickness increase degrades spatial resolution, improves relative energy resolution from 9.0% to 11.3% and increases signal-to-noise-ratio from 0.81 to 1.17. Thicker LSO crystals present greater axial sensitivity so as the detection efficiency of PET would be significantly enhanced.展开更多
目的评估人类免疫缺陷病毒(HIV)检测试剂Elecsys HIV Duo的检测性能,探讨HIV Duo的临床应用价值。方法参考临床化学定量检验程序性能验证指南评价检测方法的性能。收集广州医科大学附属市八医院2020年12月的105例初筛阳性HIV感染患者血...目的评估人类免疫缺陷病毒(HIV)检测试剂Elecsys HIV Duo的检测性能,探讨HIV Duo的临床应用价值。方法参考临床化学定量检验程序性能验证指南评价检测方法的性能。收集广州医科大学附属市八医院2020年12月的105例初筛阳性HIV感染患者血清样本,验证Elecsys HIV Duo对HIV感染不同阶段的检出能力。结果三个水平样本批内精密度分别为4.03%、0.95%、0.81%,小于6.25%(1/4 TEa),批间精密度分别为4.7%、1.23%、1.66%,小于8.33%(1/3 TEa)。使用Elecsys HIV Duo试剂检测57份含潜在干扰物质的血清样本,特异性为100%。正确度:HIV-1抗体及p24抗原阴性和阳性符合率均为100%。检测能力方面,该检测试剂针对HIV p24抗原最低检出限为0.62 U/mL,HIV-1抗体在1 NCU/mL水平下仍可检出。抗干扰能力方面,对含20 mg/L胆红素、800 mg/L血红蛋白、2000 mg/L脂肪乳剂的样本进行检测,添加干扰物质前后测定值之间符合率≥80%。对105例已知阳性样本的检测结果显示,该系统能检出不同感染时期的阳性标本。结论Elecsys HIV Duo试剂盒能够分别检测HIV-1 p24抗原和HIV抗体,在HIV抗原抗体检测中的诊断价值良好,可应用于HIV感染的早期筛查。展开更多
The object of this article is to initiate the study of a class of rings in which the right duo property is applied in relation to powers of elements and the monoid of all regular elements.Such rings shall be called ri...The object of this article is to initiate the study of a class of rings in which the right duo property is applied in relation to powers of elements and the monoid of all regular elements.Such rings shall be called right exp-DR.We investigate the structures of group rings,right quotient rings,matrix rings and(skew)polynomial rings,through the study of right exp-DR rings.In addition,we provide a method of constructing finite non-abelian p-groups for any prime p.展开更多
文摘目的寻找一种更快速、简便的人类免疫缺陷病毒(HIV)感染的筛查方法。方法对门诊和住院手术患者标本以及疾病控制中心质控标本,采用VIDAS HIV DUO Ultra方法(简称VIDAS)测定HIV p24抗原和HIV抗体,并与第3代酶联免疫吸附试验(ELISA)以及明胶粒子凝集法(PA)测定结果进行比较。结果对50份标本采用VIDAS进行检测,其敏感性和特异性分别为91.7%和92.1%。结论VIDAS可作为一种更简便的HIV检测方法,在生物安全控制方面较其他2种方法更安全有效。
文摘This is a GATE-simulation study of the Siemens Biograph DUO PET/CT system. It reports effects of changes in the thickness of the employed Lutetium Oxyorthosilicate(LSO) detectors. The PET/CT, a human body phantom and a cylindrical F-18 FDG source were simulated. Validation measurements were conducted. The results indicate that LSO thickness increase degrades spatial resolution, improves relative energy resolution from 9.0% to 11.3% and increases signal-to-noise-ratio from 0.81 to 1.17. Thicker LSO crystals present greater axial sensitivity so as the detection efficiency of PET would be significantly enhanced.
文摘目的评估人类免疫缺陷病毒(HIV)检测试剂Elecsys HIV Duo的检测性能,探讨HIV Duo的临床应用价值。方法参考临床化学定量检验程序性能验证指南评价检测方法的性能。收集广州医科大学附属市八医院2020年12月的105例初筛阳性HIV感染患者血清样本,验证Elecsys HIV Duo对HIV感染不同阶段的检出能力。结果三个水平样本批内精密度分别为4.03%、0.95%、0.81%,小于6.25%(1/4 TEa),批间精密度分别为4.7%、1.23%、1.66%,小于8.33%(1/3 TEa)。使用Elecsys HIV Duo试剂检测57份含潜在干扰物质的血清样本,特异性为100%。正确度:HIV-1抗体及p24抗原阴性和阳性符合率均为100%。检测能力方面,该检测试剂针对HIV p24抗原最低检出限为0.62 U/mL,HIV-1抗体在1 NCU/mL水平下仍可检出。抗干扰能力方面,对含20 mg/L胆红素、800 mg/L血红蛋白、2000 mg/L脂肪乳剂的样本进行检测,添加干扰物质前后测定值之间符合率≥80%。对105例已知阳性样本的检测结果显示,该系统能检出不同感染时期的阳性标本。结论Elecsys HIV Duo试剂盒能够分别检测HIV-1 p24抗原和HIV抗体,在HIV抗原抗体检测中的诊断价值良好,可应用于HIV感染的早期筛查。
文摘The object of this article is to initiate the study of a class of rings in which the right duo property is applied in relation to powers of elements and the monoid of all regular elements.Such rings shall be called right exp-DR.We investigate the structures of group rings,right quotient rings,matrix rings and(skew)polynomial rings,through the study of right exp-DR rings.In addition,we provide a method of constructing finite non-abelian p-groups for any prime p.
