Even though wind energy is a deep-rooted technology, but not yet mature and hence there are bounteous scopes for improvement to reduce the cost of wind energy. An experimental investigation has been carried out on 1:2...Even though wind energy is a deep-rooted technology, but not yet mature and hence there are bounteous scopes for improvement to reduce the cost of wind energy. An experimental investigation has been carried out on 1:25 scaled S809 aerofoil blade featuring boundary layer fence at various span wise location. Quantifying electrical power obtained by rotation of wind turbine rotor coupled with dynamic testing system. A baseline model with no flow control and an upgraded model with detachable boundary layer fence have been studied in the wind tunnel. For upgraded model, fences were placed along the location of 40% to 90% of the blade span. The rotor blades are then tested dynamically in wind tunnel at open terrain condition for 7 m/s, 9 m/s and 11 m/s velocities. In order to study the effect of boundary layer fence test has been carried out in the low speed wind tunnel having test section of size 0.9 m × 1.2 m × 2 m. Scope corder DL 750 is used to measure time varying voltage and proximity sensor with its compatible display unit is used to measure the rotor RPM. The flow behaviour was found to be considerably favourable from conventional rotor blades. Installation of fence has been found promising for increased energy extraction from air column by controlling the three dimensional span wise flow. Results demonstrate the potential of the proposed model which can obtain a maximum of about 11.8% increase in the power. In addition, the significance of the location of wing fence and blade pitch angle has been analysed.展开更多
Objective: To explore the effect of L158, 809 (angiatensin Ⅱ receptorMockers, ARBs) and Cilazapril (Angiotensin converting enzyme inhibitor, ACEI) on the expression oftransforming growth factor-β_1 (TGF-β_1) and se...Objective: To explore the effect of L158, 809 (angiatensin Ⅱ receptorMockers, ARBs) and Cilazapril (Angiotensin converting enzyme inhibitor, ACEI) on the expression oftransforming growth factor-β_1 (TGF-β_1) and secretion of fibronectin, laminin and type Ⅳcollagen from the cultured human mesangial cells . Methods: Human mesangial cells were cultured indifferent glucose (5.6 mmol/L and 30 mmol/L) and agents (1, 10, 100 and 500 μmol/L) concentrations. The proliferation of mesangial cells were detected at 24, 48 and 72 h . Then the mesangial cellsare divided into four groups, low glucose (5.6 mmol/L) control group, high glucose (30 mmol/L)control group , L158, 809 (10 μmol/L) group and cilazapril (10 μmol/L) group. Forty- eight hourslater, the expression of TGF-β_1 were detected by RT-PCR. Concentrations of TGF-β_1 ,fibronection, laminin and type Ⅳ collagen in the su-pematants of the, mesangial cells weredetermined by EUSA and radioimmunoassay methods. Results: Compared with low glucose control group,the mesangial cells under high glucose medium show excessive proliferation and more TGF-β_1,fibronectin, laminin and type Ⅳ collagen in the supernatant. The expression of TGF-β_1 mRNA wasalso significantly increased under high glucose. The levels of TGF-β_1 and ECM (extracellularmatrix) proteins in the L158, 809 group and cilazapril group are obviously lower than that of thehigh glucose control group. The expression of TGF-β_1 mRNA was markedly decreased in the L158, 809group and cilazapril group compared with that of high glucose control group . Conclusion: Highglucose stimulated the cultured human mesangial cells to excessively proliferate, express TGF-β_1and secrete ECM proteins, and the high glucose-indeced changes were suppressed by either L158, 809and cilazapril.展开更多
文摘Even though wind energy is a deep-rooted technology, but not yet mature and hence there are bounteous scopes for improvement to reduce the cost of wind energy. An experimental investigation has been carried out on 1:25 scaled S809 aerofoil blade featuring boundary layer fence at various span wise location. Quantifying electrical power obtained by rotation of wind turbine rotor coupled with dynamic testing system. A baseline model with no flow control and an upgraded model with detachable boundary layer fence have been studied in the wind tunnel. For upgraded model, fences were placed along the location of 40% to 90% of the blade span. The rotor blades are then tested dynamically in wind tunnel at open terrain condition for 7 m/s, 9 m/s and 11 m/s velocities. In order to study the effect of boundary layer fence test has been carried out in the low speed wind tunnel having test section of size 0.9 m × 1.2 m × 2 m. Scope corder DL 750 is used to measure time varying voltage and proximity sensor with its compatible display unit is used to measure the rotor RPM. The flow behaviour was found to be considerably favourable from conventional rotor blades. Installation of fence has been found promising for increased energy extraction from air column by controlling the three dimensional span wise flow. Results demonstrate the potential of the proposed model which can obtain a maximum of about 11.8% increase in the power. In addition, the significance of the location of wing fence and blade pitch angle has been analysed.
基金National Science and Technology Ninth 5-year Project of Medicine(96-906-05-0)
文摘Objective: To explore the effect of L158, 809 (angiatensin Ⅱ receptorMockers, ARBs) and Cilazapril (Angiotensin converting enzyme inhibitor, ACEI) on the expression oftransforming growth factor-β_1 (TGF-β_1) and secretion of fibronectin, laminin and type Ⅳcollagen from the cultured human mesangial cells . Methods: Human mesangial cells were cultured indifferent glucose (5.6 mmol/L and 30 mmol/L) and agents (1, 10, 100 and 500 μmol/L) concentrations. The proliferation of mesangial cells were detected at 24, 48 and 72 h . Then the mesangial cellsare divided into four groups, low glucose (5.6 mmol/L) control group, high glucose (30 mmol/L)control group , L158, 809 (10 μmol/L) group and cilazapril (10 μmol/L) group. Forty- eight hourslater, the expression of TGF-β_1 were detected by RT-PCR. Concentrations of TGF-β_1 ,fibronection, laminin and type Ⅳ collagen in the su-pematants of the, mesangial cells weredetermined by EUSA and radioimmunoassay methods. Results: Compared with low glucose control group,the mesangial cells under high glucose medium show excessive proliferation and more TGF-β_1,fibronectin, laminin and type Ⅳ collagen in the supernatant. The expression of TGF-β_1 mRNA wasalso significantly increased under high glucose. The levels of TGF-β_1 and ECM (extracellularmatrix) proteins in the L158, 809 group and cilazapril group are obviously lower than that of thehigh glucose control group. The expression of TGF-β_1 mRNA was markedly decreased in the L158, 809group and cilazapril group compared with that of high glucose control group . Conclusion: Highglucose stimulated the cultured human mesangial cells to excessively proliferate, express TGF-β_1and secrete ECM proteins, and the high glucose-indeced changes were suppressed by either L158, 809and cilazapril.
