INTRODUCTIONHepatitis B virus (HBV) is the most commonetiologic agent for infectious liver diseases. It isestimated that there are more than 250 millionchronic HBV carriersin the world today and thereis a significant ...INTRODUCTIONHepatitis B virus (HBV) is the most commonetiologic agent for infectious liver diseases. It isestimated that there are more than 250 millionchronic HBV carriersin the world today and thereis a significant association among persistentinfection, liver cirrhosis and hepatocellularcarcinoma[1-3].展开更多
The core-shell 2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane/2,4,6-Trinitrotoluene(CL-20/TNT)composite was prepared by spray-drying method in which sensitive high energy explosive(CL-20)was coated with in...The core-shell 2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane/2,4,6-Trinitrotoluene(CL-20/TNT)composite was prepared by spray-drying method in which sensitive high energy explosive(CL-20)was coated with insensitive explosive(TNT).The structure and properties of different formulations of CL-20/TNT composite and CL-20/TNT mixture were characterized by scanning electron microscopy(SEM),Transmission electron microscopy(TEM),Laser particle size analyzer,X-ray photoelectron spectroscopy(XPS),X-ray diffraction(XRD),differential scanning calorimetry(DSC),impact sensitivity test and detonation performance.The results of SEM,TEM,XPS and XRD show that e-CL-20 particles are coated by TNT.When the ratio of CL-20/TNT is 75/25,core-shell structure is well formed,and thickness of the shell is about 20e30 nm.And the analysis of heat and impact show that with the increase of TNT content,the TNT coating on the core-shell composite material can not only catalyze the thermal decomposition of core material(CL-20),but also greatly reduce the impact sensitivity.Compared with the CL-20/TNT mixture(75/25)at the same ratio,the characteristic drop height of core-shell CL-20/TNT composite(75/25)increased by 47.6%and the TNT coating can accelerate the nuclear decomposition in the CL-20/TNT composites.Therefore,the preparation of the core-shell composites can be regarded as a unique means,by which the composites are characterized by controllable decomposition rate,high energy and excellent mechanical sensitivity and could be applied to propellants and other fields.展开更多
The core inverse for a complex matrix was introduced by O. M. Baksalary and G. Trenkler. D. S. Rakic, N. C. Dincic and D. S. Djordjevc generalized the core inverse of a complex matrix to the case of an element in a ri...The core inverse for a complex matrix was introduced by O. M. Baksalary and G. Trenkler. D. S. Rakic, N. C. Dincic and D. S. Djordjevc generalized the core inverse of a complex matrix to the case of an element in a ring. They also proved that the core inverse of an element in a ring can be characterized by five equations and every core invertible element is group invertible. It is natural to ask when a group invertible element is core invertible. In this paper, we will answer this question. Let R be a ring with involution, we will use three equations to characterize the core inverse of an element. That is, let a,b ∈ R. Then a ∈ R with a= b if and only if （ab）^＊ = ab, ba^2 = a, and ab^2 = b. Finally, we investigate the additive property of two core invertible elements. Moreover, the formulae of the sum of two core invertible elements are presented.展开更多
AIM: To study persistence and replication of hepatitis C virus (HCV) in patients' peripheral blood mononuclear cells (PBMC) cultured in vitro. METHODS: Epstein Barr virus (EBV) was used to transform the hepatitis ...AIM: To study persistence and replication of hepatitis C virus (HCV) in patients' peripheral blood mononuclear cells (PBMC) cultured in vitro. METHODS: Epstein Barr virus (EBV) was used to transform the hepatitis C virus from a HCV positive patient to permanent lymphoblastoid cell lines (LCL). Positive and negative HCV RNA strands of the cultured cells and growth media were detected by reverse transcriptase-polymerase chain reaction (RT-PCR) each month. Core and NS5 proteins of HCV were further tested using immunohistochemical SP method and in situ RT-PCR. RESULTS: HCV RNA positive strands were consistently detected the cultured cells for one year. The negative-strand RNA in LCL cells and the positive-strand RNA in supernatants were observed intermittently. Immunohistochemical results medicated expression of HCV NS3 and C proteins in LCL cytoplasm mostly. The positive signal of PCR product was dark blue and mainly localized to the LCL cytoplasm. The RT-PCR signal was eliminated by overnight RNase digestion but not DNase digestion. CONCLUSION: HCV may exist and remain functional in a cultured cell line for a long period.展开更多
Under hydrothermal environment,we synthesized lanthanide ions doped sodium yttrium fluoride(NaYF4:Er,Tm@NaYF4:Ce,Tb) luminescent microcrystals via an epitaxial growth technique.The structure and morphology of these mi...Under hydrothermal environment,we synthesized lanthanide ions doped sodium yttrium fluoride(NaYF4:Er,Tm@NaYF4:Ce,Tb) luminescent microcrystals via an epitaxial growth technique.The structure and morphology of these microcrystals were examined by SEM,TEM,EDS and XRD measurements.These particles show dual-mode emissions with red upconversion(UC) and green down conversion(DC) as single particles level.The mean length and diameter of these microparticles increase from 0.43 to2.26 μm and from 1.33 to 1.86 μm,respectively.Most interestingly,the photoluminescence properties of NaYF4:Er,Tm@NaYF4:Ce,Tb phosphor crystals are highly dependent on the crystallite size.The microcrystals fluoresce emit dual-mode emissions when they are solid or dispersed in solvents.Benefiting its intensive fluorescence and uniform morphology,these materials hold great potential for security and anti-counterfeiting applications.展开更多
The sedimentary facies/microfacies,which can be correlated with well logs,determine reservoir quality and hydrocarbon productivity in carbonate rocks.The identification and evaluation of sedimentary facies/microfacies...The sedimentary facies/microfacies,which can be correlated with well logs,determine reservoir quality and hydrocarbon productivity in carbonate rocks.The identification and evaluation of sedimentary facies/microfacies using well logs are very important in order to effectively guide the exploration and development of oil and gas.Previous carbonate facies/microfacies identification methods based on conventional well log data often exist multiple solutions.This paper presents a new method of facies/microfacies identification based on core-conventional logs-electrical image log-geological model,and the method is applied in the fourth member of the Dengying Formation(Deng 4)in the Gaoshiti-Moxi area of the Sichuan Basin.Firstly,core data are used to calibrate different types of facies/microfacies,with the aim to systematically clarify the conventional and electrical image log responses for each type of facies/microfacies.Secondly,through the pair wise correlation analysis of conventional logs,GR,RT and CNL,are selected as sensitive curves to establish the microfacies discrimination criteria separately.Thirdly,five well logging response models and identification charts of facies/microfacies are established based on electrical image log.The sedimentary microfacies of 60 exploratory wells was analyzed individually through this method,and the microfacies maps of 4 layers of the Deng 4 Member were compiled,and the plane distribution of microfacies in the Gaoshiti-Moxi area of the Sichuan Basin was depicted.The comparative analysis of oil testing or production results of wells reveals three most favorable types of microfacies and they include algal psammitic shoal,algal agglutinate mound,and algal stromatolite mound,which provide a reliable technical support to the exploration,development and well deployment in the study area.展开更多
采用改进的两步法在原位基础上合成了以纳米零价铁(nano Zero Valent Iron,nZVI)为核芯的核壳型介孔二氧化硅(nZVI@mesoSiO_2).同时,通过简单地调控铁源用量得到具有单一nZVI核芯和不同壳层厚度的核壳型纳米复合材料.结果发现,铁源用量...采用改进的两步法在原位基础上合成了以纳米零价铁(nano Zero Valent Iron,nZVI)为核芯的核壳型介孔二氧化硅(nZVI@mesoSiO_2).同时,通过简单地调控铁源用量得到具有单一nZVI核芯和不同壳层厚度的核壳型纳米复合材料.结果发现,铁源用量的增加会导致核芯尺寸减小、壳层厚度增加及颗粒比表面积下降.当铁源用量为2.78 g时,得到的nZVI@mesoSiO_2不仅具有较高的比表面积和单一且均匀的孔径分布,而且对2,4,6-三氯苯酚(2,4,6-Trichlorophenol, 2,4,6-TCP)的去除表现出很高的性能.影响因素实验表明,材料的最佳投加量为1.0 g·L^(-1),体系适宜初始pH为5.0,污染物初始浓度升高会导致去除效果下降,并且反应体系内乙二胺四乙酸(EDTA)的存在可以提高2,4,6-TCP的去除率.材料的重复利用实验结果表明,经过多次循环反应后会导致材料nZVI核芯的失活和孔道的堵塞.本研究不仅为制备可控壳层厚度的核壳型介孔材料提供了理论指导,而且为进一步改性合成对2,4,6-TP具有高选择性的复合材料提供了依据.展开更多
GREENHOUSE gases such as CH<sub>4</sub> in the ancient atmospheric concentration can be reconstructed by extracting and analyzing the gases trapped in polar ice core bubbles. It is a new attempt to extract...GREENHOUSE gases such as CH<sub>4</sub> in the ancient atmospheric concentration can be reconstructed by extracting and analyzing the gases trapped in polar ice core bubbles. It is a new attempt to extract and analyze the CH<sub>4</sub> concentration in Dunde ice core for the study of mountain glacier. Samples were taken from the about 140-m ice core drilled in 1987 in Dunde ice cap in Qilian Mountain. The ice core has been well preserved in cold room. 12 samples were taken from the upper 95 m, and cut to 15 cm in length and 5cm in diameter. CH<sub>4</sub> concentrations were measured in CNRS Laboratory of Glaciology, Grenoble, France.展开更多
本文利用第四代地磁场综合模型(Comprehensive Model 4,CM4),计算了1982—2002年隆尧地磁台站的磁层源磁场及其感应场、电离层源磁场及其感应场的地磁北向分量X、东向分量Y、垂直分量Z,分析了各场源磁场随时间的变化特征。磁层源磁场及...本文利用第四代地磁场综合模型(Comprehensive Model 4,CM4),计算了1982—2002年隆尧地磁台站的磁层源磁场及其感应场、电离层源磁场及其感应场的地磁北向分量X、东向分量Y、垂直分量Z,分析了各场源磁场随时间的变化特征。磁层源磁场及其感应场呈现出11年和27天的周期性变化,有些年的27天周期性变化显著,有些年则不太显著;电离层源磁场及其感应场具有明显的季节变化,不同年相同季节的变化形态一致但幅度不同;日变化分析显示,磁静日和磁扰日期间的模型数据与台站实测数据变化一致性较好,相关性较高。展开更多
基金Project supported by the grant from Science Foundation of Ministry of Health of China, No. 96-1-347.
文摘INTRODUCTIONHepatitis B virus (HBV) is the most commonetiologic agent for infectious liver diseases. It isestimated that there are more than 250 millionchronic HBV carriersin the world today and thereis a significant association among persistentinfection, liver cirrhosis and hepatocellularcarcinoma[1-3].
文摘The core-shell 2,4,6,8,10,12-Hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane/2,4,6-Trinitrotoluene(CL-20/TNT)composite was prepared by spray-drying method in which sensitive high energy explosive(CL-20)was coated with insensitive explosive(TNT).The structure and properties of different formulations of CL-20/TNT composite and CL-20/TNT mixture were characterized by scanning electron microscopy(SEM),Transmission electron microscopy(TEM),Laser particle size analyzer,X-ray photoelectron spectroscopy(XPS),X-ray diffraction(XRD),differential scanning calorimetry(DSC),impact sensitivity test and detonation performance.The results of SEM,TEM,XPS and XRD show that e-CL-20 particles are coated by TNT.When the ratio of CL-20/TNT is 75/25,core-shell structure is well formed,and thickness of the shell is about 20e30 nm.And the analysis of heat and impact show that with the increase of TNT content,the TNT coating on the core-shell composite material can not only catalyze the thermal decomposition of core material(CL-20),but also greatly reduce the impact sensitivity.Compared with the CL-20/TNT mixture(75/25)at the same ratio,the characteristic drop height of core-shell CL-20/TNT composite(75/25)increased by 47.6%and the TNT coating can accelerate the nuclear decomposition in the CL-20/TNT composites.Therefore,the preparation of the core-shell composites can be regarded as a unique means,by which the composites are characterized by controllable decomposition rate,high energy and excellent mechanical sensitivity and could be applied to propellants and other fields.
基金Acknowledgements This work was supported by the National Natural Science Foundation of China （Grant Nos. 11201063, 11371089）, the Specialized Research Fund for the Doctoral Program of Higher Education （No. 20120092110020）, the Jiangsu Planned Projects for Postdoctoral Research Funds （No. 1501048B）, and the Natural Science Foundation of Jiangsu Province （No. BK20141327）.
文摘The core inverse for a complex matrix was introduced by O. M. Baksalary and G. Trenkler. D. S. Rakic, N. C. Dincic and D. S. Djordjevc generalized the core inverse of a complex matrix to the case of an element in a ring. They also proved that the core inverse of an element in a ring can be characterized by five equations and every core invertible element is group invertible. It is natural to ask when a group invertible element is core invertible. In this paper, we will answer this question. Let R be a ring with involution, we will use three equations to characterize the core inverse of an element. That is, let a,b ∈ R. Then a ∈ R with a= b if and only if （ab）^＊ = ab, ba^2 = a, and ab^2 = b. Finally, we investigate the additive property of two core invertible elements. Moreover, the formulae of the sum of two core invertible elements are presented.
基金The paper was support by a grant from the Ministry Youth Research of China,No.98-1-269
文摘AIM: To study persistence and replication of hepatitis C virus (HCV) in patients' peripheral blood mononuclear cells (PBMC) cultured in vitro. METHODS: Epstein Barr virus (EBV) was used to transform the hepatitis C virus from a HCV positive patient to permanent lymphoblastoid cell lines (LCL). Positive and negative HCV RNA strands of the cultured cells and growth media were detected by reverse transcriptase-polymerase chain reaction (RT-PCR) each month. Core and NS5 proteins of HCV were further tested using immunohistochemical SP method and in situ RT-PCR. RESULTS: HCV RNA positive strands were consistently detected the cultured cells for one year. The negative-strand RNA in LCL cells and the positive-strand RNA in supernatants were observed intermittently. Immunohistochemical results medicated expression of HCV NS3 and C proteins in LCL cytoplasm mostly. The positive signal of PCR product was dark blue and mainly localized to the LCL cytoplasm. The RT-PCR signal was eliminated by overnight RNase digestion but not DNase digestion. CONCLUSION: HCV may exist and remain functional in a cultured cell line for a long period.
基金Project supported by the National Natural Science Foundation of China (21271074,51372091)the Teamwork Projects funded by the Guangdong Natural Science Foundation (S2013030012842)+1 种基金Guangdong Provincial Science&Technology Project (2015B090903074)Guangzhou Science&Technology Project (201605030005)。
文摘Under hydrothermal environment,we synthesized lanthanide ions doped sodium yttrium fluoride(NaYF4:Er,Tm@NaYF4:Ce,Tb) luminescent microcrystals via an epitaxial growth technique.The structure and morphology of these microcrystals were examined by SEM,TEM,EDS and XRD measurements.These particles show dual-mode emissions with red upconversion(UC) and green down conversion(DC) as single particles level.The mean length and diameter of these microparticles increase from 0.43 to2.26 μm and from 1.33 to 1.86 μm,respectively.Most interestingly,the photoluminescence properties of NaYF4:Er,Tm@NaYF4:Ce,Tb phosphor crystals are highly dependent on the crystallite size.The microcrystals fluoresce emit dual-mode emissions when they are solid or dispersed in solvents.Benefiting its intensive fluorescence and uniform morphology,these materials hold great potential for security and anti-counterfeiting applications.
基金financially supported by oil and gas accumulation patterns,key technologies and targets evaluation of Lower Paleozoic-Precambrian carbonate rocks(No.2016ZX05004)。
文摘The sedimentary facies/microfacies,which can be correlated with well logs,determine reservoir quality and hydrocarbon productivity in carbonate rocks.The identification and evaluation of sedimentary facies/microfacies using well logs are very important in order to effectively guide the exploration and development of oil and gas.Previous carbonate facies/microfacies identification methods based on conventional well log data often exist multiple solutions.This paper presents a new method of facies/microfacies identification based on core-conventional logs-electrical image log-geological model,and the method is applied in the fourth member of the Dengying Formation(Deng 4)in the Gaoshiti-Moxi area of the Sichuan Basin.Firstly,core data are used to calibrate different types of facies/microfacies,with the aim to systematically clarify the conventional and electrical image log responses for each type of facies/microfacies.Secondly,through the pair wise correlation analysis of conventional logs,GR,RT and CNL,are selected as sensitive curves to establish the microfacies discrimination criteria separately.Thirdly,five well logging response models and identification charts of facies/microfacies are established based on electrical image log.The sedimentary microfacies of 60 exploratory wells was analyzed individually through this method,and the microfacies maps of 4 layers of the Deng 4 Member were compiled,and the plane distribution of microfacies in the Gaoshiti-Moxi area of the Sichuan Basin was depicted.The comparative analysis of oil testing or production results of wells reveals three most favorable types of microfacies and they include algal psammitic shoal,algal agglutinate mound,and algal stromatolite mound,which provide a reliable technical support to the exploration,development and well deployment in the study area.
文摘GREENHOUSE gases such as CH<sub>4</sub> in the ancient atmospheric concentration can be reconstructed by extracting and analyzing the gases trapped in polar ice core bubbles. It is a new attempt to extract and analyze the CH<sub>4</sub> concentration in Dunde ice core for the study of mountain glacier. Samples were taken from the about 140-m ice core drilled in 1987 in Dunde ice cap in Qilian Mountain. The ice core has been well preserved in cold room. 12 samples were taken from the upper 95 m, and cut to 15 cm in length and 5cm in diameter. CH<sub>4</sub> concentrations were measured in CNRS Laboratory of Glaciology, Grenoble, France.
文摘本文利用第四代地磁场综合模型(Comprehensive Model 4,CM4),计算了1982—2002年隆尧地磁台站的磁层源磁场及其感应场、电离层源磁场及其感应场的地磁北向分量X、东向分量Y、垂直分量Z,分析了各场源磁场随时间的变化特征。磁层源磁场及其感应场呈现出11年和27天的周期性变化,有些年的27天周期性变化显著,有些年则不太显著;电离层源磁场及其感应场具有明显的季节变化,不同年相同季节的变化形态一致但幅度不同;日变化分析显示,磁静日和磁扰日期间的模型数据与台站实测数据变化一致性较好,相关性较高。
