1,3,5-Trisubstituted pyrazolines are rapidly and conveniently oxidized to their corresponding pyrazoles by 1,3-dichloro-5,5- dimethylhydantoin（DCH） in solution and solvent-free conditions under microwave irradiation...1,3,5-Trisubstituted pyrazolines are rapidly and conveniently oxidized to their corresponding pyrazoles by 1,3-dichloro-5,5- dimethylhydantoin（DCH） in solution and solvent-free conditions under microwave irradiation.The presence of silica gel as a supporting agent is shown to be effective in reducing the reaction times and increasing the yields.展开更多
文摘1,3,5-Trisubstituted pyrazolines are rapidly and conveniently oxidized to their corresponding pyrazoles by 1,3-dichloro-5,5- dimethylhydantoin（DCH） in solution and solvent-free conditions under microwave irradiation.The presence of silica gel as a supporting agent is shown to be effective in reducing the reaction times and increasing the yields.
