Many sources of stress cause accumulation of unfolded or misfolded proteins in endoplasmic reticulum(ER), which elicits the unfolded protein response(UPR) to either promote cell survival or programmed cell death depen...Many sources of stress cause accumulation of unfolded or misfolded proteins in endoplasmic reticulum(ER), which elicits the unfolded protein response(UPR) to either promote cell survival or programmed cell death depending on different developmental context or stress severity. The Arabidopsis membrane-associated transcription factor, b ZIP28, is the functional equivalent of mammalian ATF6, which relocates from the ER to the Golgi where it is proteolytically processed and released from the membrane to the nucleus to mediate the UPR. Although the canonical site-1 protease(S1P) cleavage site on the ER lumen-facing domain is well conserved between b ZIP28 and ATF6, the importance of S1 P cleavage on b ZIP28 has not been experimentally demonstrated. Here we provide genetic evidence that the RRIL573 site, but not the RVLM373 site, on the lumen-facing domain of bZ IP28 is critical for the biological function of b ZIP28 under ER stress condition. Further biochemistry and cell biology studies demonstrated that the RRIL573 site, but not the RVLM373 site, is required for proteolytic processing and nuclear relocation of b ZIP28 in response to ER stress. Our results reveal that S1 P cleavage site plays a pivotal role in activation and function of b ZIP28 during UPR in plants.展开更多
2P DC 1500 V框架隔离开关适用于光伏、储能系统。这类产品相比老产品而言更具成本上的优势。产品主要的设计改进点为:修改机构连杆加大开距;主弧触头、窄缝灭弧技术通过临界电流试验;电场磁场的仿真设计专用灭弧以及绝缘技术保证灭弧...2P DC 1500 V框架隔离开关适用于光伏、储能系统。这类产品相比老产品而言更具成本上的优势。产品主要的设计改进点为:修改机构连杆加大开距;主弧触头、窄缝灭弧技术通过临界电流试验;电场磁场的仿真设计专用灭弧以及绝缘技术保证灭弧可靠通过电寿命试验。经试验验证,2P DC 1500 V框架隔离开关符合标准要求。展开更多
针对新能源汽车控制器开发周期长、无法快速进行小批量生产等问题,该文应用基于模型的快速开发方法进行永磁同步电机控制算法开发。文中先分析了永磁同步电机的数学模型,在此基础上设计了速度环的ADRC算法;然后在D2P(development to pro...针对新能源汽车控制器开发周期长、无法快速进行小批量生产等问题,该文应用基于模型的快速开发方法进行永磁同步电机控制算法开发。文中先分析了永磁同步电机的数学模型,在此基础上设计了速度环的ADRC算法;然后在D2P(development to production)平台下,搭建车用永磁同步电机矢量控制代码模型,以及代码自动生成和仿真验证;最后进行台架试验,验证控制算法,在线整定参数,实现控制算法的快速开发。实验结果表明,采用基于模型的快速开发方法能够缩短开发周期和成本,并且自动生成的代码具有较高的可靠性,能满足新能源汽车各项性能要求。展开更多
Let F be a number field and p be a prime. In the successive approximation theorem, we prove that, for each integer n ≥ 1, finitely many candidates for the Galois group of the nth stage of the p-class tower over F are...Let F be a number field and p be a prime. In the successive approximation theorem, we prove that, for each integer n ≥ 1, finitely many candidates for the Galois group of the nth stage of the p-class tower over F are determined by abelian type invariants of p-class groups C1pE of unramified extensions E/F with degree [E : F] = pn-1. Illustrated by the most extensive numerical results available currently, the transfer kernels (TE, F) of the p-class extensions TE, F : C1pF → C1pE from F to unramified cyclic degree-p extensions E/F are shown to be capable of narrowing down the number of contestants significantly. By determining the isomorphism type of the maximal subgroups S G of all 3-groups G with coclass cc(G) = 1, and establishing a general theorem on the connection between the p-class towers of a number field F and of an unramified abelian p-extension E/F, we are able to provide a theoretical proof of the realization of certain 3-groups S with maximal class by 3-tower groups of dihedral fields E with degree 6, which could not be realized up to now.展开更多
Let p be a prime. For any finite p-group G, the deep transfers T H,G ' : H / H ' → G ' / G " from the maximal subgroups H of index (G:H) = p in G to the derived subgroup G ' are introduced as an ...Let p be a prime. For any finite p-group G, the deep transfers T H,G ' : H / H ' → G ' / G " from the maximal subgroups H of index (G:H) = p in G to the derived subgroup G ' are introduced as an innovative tool for identifying G uniquely by means of the family of kernels ùd(G) =(ker(T H,G ')) (G: H) = p. For all finite 3-groups G of coclass cc(G) = 1, the family ùd(G) is determined explicitly. The results are applied to the Galois groups G =Gal(F3 (∞)/ F) of the Hilbert 3-class towers of all real quadratic fields F = Q(√d) with fundamental discriminants d > 1, 3-class group Cl3(F) □ C3 × C3, and total 3-principalization in each of their four unramified cyclic cubic extensions E/F. A systematic statistical evaluation is given for the complete range 1 d 7, and a few exceptional cases are pointed out for 1 d 8.展开更多
In the present work,we extend the Coulomb and Proximity Potential Model(CPPM)to study two-proton(2p)radioactivity from excited states while the proximity potential is chosen as AW95 proposed by Aage Withner in 1995.De...In the present work,we extend the Coulomb and Proximity Potential Model(CPPM)to study two-proton(2p)radioactivity from excited states while the proximity potential is chosen as AW95 proposed by Aage Withner in 1995.Demonstration reveals that the theoretical results acquired by CPPM exhibit a high level of consistency with prior theoretical models such as the unified fission model(UFM),generalized liquid-drop model(GLDM)and effective liquid-drop model(ELDM).Furthermore,within the CPPM,we predicted the half-lives of potential 2p radioactive nuclei for which experimental data are currently unavailable.The predicted results were then assessed,compared with UFM,ELDM and GLDM models,and examined in detail.展开更多
Agropyron cristatum(2n=4x=28,PPPP)is a wild relative of common wheat which contains a large number of desirable genes that can be exploited for wheat improvement.Wheat–A.cristatum 2P alien translocation lines exhibit...Agropyron cristatum(2n=4x=28,PPPP)is a wild relative of common wheat which contains a large number of desirable genes that can be exploited for wheat improvement.Wheat–A.cristatum 2P alien translocation lines exhibit many desirable traits,such as small flag leaves,a high spikelet number and density,and a compact plant type.An agronomic trait evaluation and a genetic analysis were carried out on translocation lines and backcross populations of these lines carrying different translocation fragments.The results showed that a translocation fragment from 2PT-3(2PL)reduced the length of the flag leaves,while translocation fragments from 2PT-3(2PL)and 2PT-5(2PL(0.60–1.00))reduced the width of the flag leaves.A translocation fragment from 2PT-13(2PS(0.18–0.36))increased the length and area of the flag leaves.Translocation fragments from 2PT-3(2PL)and 2PT-8(2PL(0.86–1.00))increased the density of spikelets.Translocation fragments from 2PT-7(2PL(0.00–0.09)),2PT-8(2PL(0.86–1.00)),2PT-10(2PS),and 2PT-13(2PS(0.18–0.36))reduced plant height.This study provides a scientific basis for the effective utilization of wheat–A.cristatum translocation lines.展开更多
在线P2P(peer-to-pear)借贷是一种新兴的在线个人财富分配和管理系统,它允许投资人直接对借款人创建的借款标的进行竞标和投资.在P2P借贷平台中,存在一个重要的问题即如何合理分配投资人的投资金额给合适的借款人.针对该问题,提出了一...在线P2P(peer-to-pear)借贷是一种新兴的在线个人财富分配和管理系统,它允许投资人直接对借款人创建的借款标的进行竞标和投资.在P2P借贷平台中,存在一个重要的问题即如何合理分配投资人的投资金额给合适的借款人.针对该问题,提出了一种基于风险和剩余价值最大化的投资推荐框架RTSM(risk total surplus maximize).RTSM首先对借款标的进行风险评估,然后基于经济学中的剩余价值理论,使用投资人和借款人在有风险情况下的剩余价值假设,将风险评估与投资推荐结合在一起,为投资人推荐高收益低风险的投资决策.实验在风险评估和投资推荐2个阶段对美国和中国知名的P2P借贷平台(Prosper、拍拍贷)的真实数据进行分析和验证.从实验结果可以看出:RTSM可以更好地降低风险和提高投资人与借款人的整体利益.展开更多
In this study,we systematically investigated the two-proton(2p)radioactivity half-lives from the excited state of nuclei near the proton drip line within the Gamowlike model(GLM)and modified Gamow-like model(MGLM).The...In this study,we systematically investigated the two-proton(2p)radioactivity half-lives from the excited state of nuclei near the proton drip line within the Gamowlike model(GLM)and modified Gamow-like model(MGLM).The calculated results were highly consistent with the theoretical values obtained using the unified fission model[Chin.Phys.C 45,124105(2021)],effective liquid drop model,and generalized liquid drop model[Acta Phys.Sin 71,062301(2022)].Furthermore,utilizing the GLM and MGLM,we predicted the 2p radioactivity halflives from the excited state for some nuclei that are not yet available experimentally.Simultaneously,by analyzing the calculated results from these theoretical models,it was found that the half-lives are strongly dependent on Qand l.展开更多
基金supported by grants from the National Basic Research Program of China(973 Program,2012CB910500)the National Natural Science Foundation of China(31171157,31222008)the Specialized Research Fund for the Doctoral Program of Higher Education(20130071110011)
文摘Many sources of stress cause accumulation of unfolded or misfolded proteins in endoplasmic reticulum(ER), which elicits the unfolded protein response(UPR) to either promote cell survival or programmed cell death depending on different developmental context or stress severity. The Arabidopsis membrane-associated transcription factor, b ZIP28, is the functional equivalent of mammalian ATF6, which relocates from the ER to the Golgi where it is proteolytically processed and released from the membrane to the nucleus to mediate the UPR. Although the canonical site-1 protease(S1P) cleavage site on the ER lumen-facing domain is well conserved between b ZIP28 and ATF6, the importance of S1 P cleavage on b ZIP28 has not been experimentally demonstrated. Here we provide genetic evidence that the RRIL573 site, but not the RVLM373 site, on the lumen-facing domain of bZ IP28 is critical for the biological function of b ZIP28 under ER stress condition. Further biochemistry and cell biology studies demonstrated that the RRIL573 site, but not the RVLM373 site, is required for proteolytic processing and nuclear relocation of b ZIP28 in response to ER stress. Our results reveal that S1 P cleavage site plays a pivotal role in activation and function of b ZIP28 during UPR in plants.
文摘2P DC 1500 V框架隔离开关适用于光伏、储能系统。这类产品相比老产品而言更具成本上的优势。产品主要的设计改进点为:修改机构连杆加大开距;主弧触头、窄缝灭弧技术通过临界电流试验;电场磁场的仿真设计专用灭弧以及绝缘技术保证灭弧可靠通过电寿命试验。经试验验证,2P DC 1500 V框架隔离开关符合标准要求。
文摘针对新能源汽车控制器开发周期长、无法快速进行小批量生产等问题,该文应用基于模型的快速开发方法进行永磁同步电机控制算法开发。文中先分析了永磁同步电机的数学模型,在此基础上设计了速度环的ADRC算法;然后在D2P(development to production)平台下,搭建车用永磁同步电机矢量控制代码模型,以及代码自动生成和仿真验证;最后进行台架试验,验证控制算法,在线整定参数,实现控制算法的快速开发。实验结果表明,采用基于模型的快速开发方法能够缩短开发周期和成本,并且自动生成的代码具有较高的可靠性,能满足新能源汽车各项性能要求。
文摘Let F be a number field and p be a prime. In the successive approximation theorem, we prove that, for each integer n ≥ 1, finitely many candidates for the Galois group of the nth stage of the p-class tower over F are determined by abelian type invariants of p-class groups C1pE of unramified extensions E/F with degree [E : F] = pn-1. Illustrated by the most extensive numerical results available currently, the transfer kernels (TE, F) of the p-class extensions TE, F : C1pF → C1pE from F to unramified cyclic degree-p extensions E/F are shown to be capable of narrowing down the number of contestants significantly. By determining the isomorphism type of the maximal subgroups S G of all 3-groups G with coclass cc(G) = 1, and establishing a general theorem on the connection between the p-class towers of a number field F and of an unramified abelian p-extension E/F, we are able to provide a theoretical proof of the realization of certain 3-groups S with maximal class by 3-tower groups of dihedral fields E with degree 6, which could not be realized up to now.
文摘Let p be a prime. For any finite p-group G, the deep transfers T H,G ' : H / H ' → G ' / G " from the maximal subgroups H of index (G:H) = p in G to the derived subgroup G ' are introduced as an innovative tool for identifying G uniquely by means of the family of kernels ùd(G) =(ker(T H,G ')) (G: H) = p. For all finite 3-groups G of coclass cc(G) = 1, the family ùd(G) is determined explicitly. The results are applied to the Galois groups G =Gal(F3 (∞)/ F) of the Hilbert 3-class towers of all real quadratic fields F = Q(√d) with fundamental discriminants d > 1, 3-class group Cl3(F) □ C3 × C3, and total 3-principalization in each of their four unramified cyclic cubic extensions E/F. A systematic statistical evaluation is given for the complete range 1 d 7, and a few exceptional cases are pointed out for 1 d 8.
基金supported by the National Natural Science Foundation of China(Nos.12175100 and 11975132)the Construct Program of the Key Discipline in Hunan Province,the Research Foundation of Education Bureau of Hunan Province,China(No.18A237)+1 种基金the Natural Science Foundation of Hunan Province,China(No.2018JJ2321)the Innovation Group of Nuclear and Particle Physics in USC,the Opening Project of Cooperative Innovation Center for Nuclear Fuel Cycle Technology and Equipment,University of South China(No.2019KFZ10).
文摘In the present work,we extend the Coulomb and Proximity Potential Model(CPPM)to study two-proton(2p)radioactivity from excited states while the proximity potential is chosen as AW95 proposed by Aage Withner in 1995.Demonstration reveals that the theoretical results acquired by CPPM exhibit a high level of consistency with prior theoretical models such as the unified fission model(UFM),generalized liquid-drop model(GLDM)and effective liquid-drop model(ELDM).Furthermore,within the CPPM,we predicted the half-lives of potential 2p radioactive nuclei for which experimental data are currently unavailable.The predicted results were then assessed,compared with UFM,ELDM and GLDM models,and examined in detail.
基金supported by grants from the National Natural Science Foundation of China(32272083)the National Key Research and Development Program of China(2016YFD0100102).
文摘Agropyron cristatum(2n=4x=28,PPPP)is a wild relative of common wheat which contains a large number of desirable genes that can be exploited for wheat improvement.Wheat–A.cristatum 2P alien translocation lines exhibit many desirable traits,such as small flag leaves,a high spikelet number and density,and a compact plant type.An agronomic trait evaluation and a genetic analysis were carried out on translocation lines and backcross populations of these lines carrying different translocation fragments.The results showed that a translocation fragment from 2PT-3(2PL)reduced the length of the flag leaves,while translocation fragments from 2PT-3(2PL)and 2PT-5(2PL(0.60–1.00))reduced the width of the flag leaves.A translocation fragment from 2PT-13(2PS(0.18–0.36))increased the length and area of the flag leaves.Translocation fragments from 2PT-3(2PL)and 2PT-8(2PL(0.86–1.00))increased the density of spikelets.Translocation fragments from 2PT-7(2PL(0.00–0.09)),2PT-8(2PL(0.86–1.00)),2PT-10(2PS),and 2PT-13(2PS(0.18–0.36))reduced plant height.This study provides a scientific basis for the effective utilization of wheat–A.cristatum translocation lines.
文摘在线P2P(peer-to-pear)借贷是一种新兴的在线个人财富分配和管理系统,它允许投资人直接对借款人创建的借款标的进行竞标和投资.在P2P借贷平台中,存在一个重要的问题即如何合理分配投资人的投资金额给合适的借款人.针对该问题,提出了一种基于风险和剩余价值最大化的投资推荐框架RTSM(risk total surplus maximize).RTSM首先对借款标的进行风险评估,然后基于经济学中的剩余价值理论,使用投资人和借款人在有风险情况下的剩余价值假设,将风险评估与投资推荐结合在一起,为投资人推荐高收益低风险的投资决策.实验在风险评估和投资推荐2个阶段对美国和中国知名的P2P借贷平台(Prosper、拍拍贷)的真实数据进行分析和验证.从实验结果可以看出:RTSM可以更好地降低风险和提高投资人与借款人的整体利益.
基金supported by the National Natural Science Foundation of China(Nos.12175100 and 11975132)the Construct Program of the Key Discipline in Hunan Province+3 种基金the Research Foundation of the Education Bureau of Hunan Province,China(No.18A237)the Natural Science Foundation of Hunan Province,China(No.2018JJ2321)the Innovation Group of Nuclear and Particle Physics in USCthe Opening Project of the Cooperative Innovation Center for Nuclear Fuel Cycle Technology and Equipment,University of South China(No.2019KFZ10)。
文摘In this study,we systematically investigated the two-proton(2p)radioactivity half-lives from the excited state of nuclei near the proton drip line within the Gamowlike model(GLM)and modified Gamow-like model(MGLM).The calculated results were highly consistent with the theoretical values obtained using the unified fission model[Chin.Phys.C 45,124105(2021)],effective liquid drop model,and generalized liquid drop model[Acta Phys.Sin 71,062301(2022)].Furthermore,utilizing the GLM and MGLM,we predicted the 2p radioactivity halflives from the excited state for some nuclei that are not yet available experimentally.Simultaneously,by analyzing the calculated results from these theoretical models,it was found that the half-lives are strongly dependent on Qand l.
