The paper makes some analyses on 11 trace elements in the Milanggouwan stratigraphical section in the Salawusu River valley, which is regarded as a prototype geology-palaeoclimate record since 150 ka BP. The results s...The paper makes some analyses on 11 trace elements in the Milanggouwan stratigraphical section in the Salawusu River valley, which is regarded as a prototype geology-palaeoclimate record since 150 ka BP. The results show that the content and variation of trace elements has experienced remarkably regular changes in the pace with coarse and fine sedimentary cycles of palaeo-aeolian sands to its overlying fluvio-lacustrine facies or/and palaeosols. The trace elements with chemical properties of relatively active (V, Sr, Cu, Ni, As) and relatively stable (P, Pb, Rb, Mn, Nb, Zr) are a manifestation of the corresponding 27 changeable cycles between peak and valley values, appearing a multi-fiuctuational process line of relative gathering and migration since then. The low numerical value distribution of these two types of trace elements in the aeolian sand facies represents erosion and accumulation under wind force during the cold-dry climate. Whereas their enrichments in both fluvio-lacustrine facies and palaeosols are related to the valley’s special low-lying physiognomic position between the Ordos Plateau and the Loess Plateau under the warm and humid climate conditions. The above relatively migrated and gathered change of the trace elements is the result of 27 climatic cycles of cold-dry and warm-humid, which is probably caused by repeated alternations of winter monsoon and summer monsoon in the Mu Us Sandy Land influenced by the climate vicissitudes in northern hemisphere during glacial and interglacial periods since 150 ka BP.展开更多
Milanggouwan stratigraphical section" named lately takes down 27 cycles of alternately evolutionary histories of desert depositions in the Mu Us area with the fluviolacustrine facies and palaeosols since 150 ka B...Milanggouwan stratigraphical section" named lately takes down 27 cycles of alternately evolutionary histories of desert depositions in the Mu Us area with the fluviolacustrine facies and palaeosols since 150 ka B.P. Studies show that the sedimentary form was induced by the growth and decline and confrontation each other between the winter monsoon and the summer monsoon of East Asia in the past 150 ka.展开更多
Erectile dysfunction(ED)is increasing in prevalence,with estimates that 50%of men between 40 and 70 years of age suffer from the disease.Due to a wide array of available medical interventions,significant focus has bee...Erectile dysfunction(ED)is increasing in prevalence,with estimates that 50%of men between 40 and 70 years of age suffer from the disease.Due to a wide array of available medical interventions,significant focus has been put on combination therapies that can treat ED refractory to first-line treatments such as phosphodiesterase 5 inhibitors(PDE5is).However,reviews evaluating monotherapy noninferiority and patient satisfaction of monotherapy versus combination therapy are lacking.A thorough PubMed search was performed to evaluate combination therapy in ED treatment.Articles published between January 2008 and June 2023 were reviewed,including randomized control trials,retrospective analyses,and cohort studies.Combination therapies included PDE5i plus another PDE5i,testosterone supplementation,α-blockers,vacuum erectile devices,intracavernosal injections,and low-intensity shockwave therapy.Based on this review,PDE5i monotherapy is not inferior to combination therapy and has increased satisfaction,convenience,and ease of use for patients with ED.Limitations of current literature on combination therapy include small sample size,limited data on patient satisfaction,possible biases,and limited follow-up time.Further studies will need larger randomized control trials with follow-up times greater than 1 year.展开更多
The Jiama porphyry copper deposit in Tibet is one of the proven supergiant copper deposits in the Qinghai-Tibet Plateau at present,with the reserves of geological resources equivalent to nearly 20×10^(6) t.Howeve...The Jiama porphyry copper deposit in Tibet is one of the proven supergiant copper deposits in the Qinghai-Tibet Plateau at present,with the reserves of geological resources equivalent to nearly 20×10^(6) t.However,it features wavy and steep terrain,leading to extremely difficult field operation and heavy interference.This study attempts to determine the effects of the tensor controlled-source audiomagnetotellurics(CSAMT)with high-power orthogonal signal sources(also referred to as the high-power tensor CSAMT)when it is applied to the deep geophysical exploration in plateaus with complex terrain and mining areas with strong interference.The test results show that the high current provided by the highpower tensor CSAMT not only greatly improved the signal-to-noise ratio but also guaranteed that effective signals were received in the case of a long transmitter-receiver distance.Meanwhile,the tensor data better described the anisotropy of deep geologic bodies.In addition,the tests also show that when the transmitting current reaches 60 A,it is still guaranteed that strong enough signals can be received in the case of the transmitter-receiver distance of about 25 km,sounding curves show no near field effect,and effective exploration depth can reach 3 km.The 2D inversion results are roughly consistent with drilling results,indicating that the high-power tensor CSAMT can be used to achieve nearly actual characteristics of underground electrical structures.Therefore,this method has great potential for application in deep geophysical exploration in plateaus and mining areas with complex terrain and strong interference,respectively.This study not only serves as important guidance on the prospecting in the Qinghai-Tibet Plateau but also can be used as positive references for deep mineral exploration in other areas.展开更多
基金National Natural Science Foundation of China, No. 49971009State Key Laboratory of Loess and Quaternary Geology,Institute of Earth Environment, CAS, No. SKLLQG0008+1 种基金National Key Project for Basic Research No. G2000048701
文摘The paper makes some analyses on 11 trace elements in the Milanggouwan stratigraphical section in the Salawusu River valley, which is regarded as a prototype geology-palaeoclimate record since 150 ka BP. The results show that the content and variation of trace elements has experienced remarkably regular changes in the pace with coarse and fine sedimentary cycles of palaeo-aeolian sands to its overlying fluvio-lacustrine facies or/and palaeosols. The trace elements with chemical properties of relatively active (V, Sr, Cu, Ni, As) and relatively stable (P, Pb, Rb, Mn, Nb, Zr) are a manifestation of the corresponding 27 changeable cycles between peak and valley values, appearing a multi-fiuctuational process line of relative gathering and migration since then. The low numerical value distribution of these two types of trace elements in the aeolian sand facies represents erosion and accumulation under wind force during the cold-dry climate. Whereas their enrichments in both fluvio-lacustrine facies and palaeosols are related to the valley’s special low-lying physiognomic position between the Ordos Plateau and the Loess Plateau under the warm and humid climate conditions. The above relatively migrated and gathered change of the trace elements is the result of 27 climatic cycles of cold-dry and warm-humid, which is probably caused by repeated alternations of winter monsoon and summer monsoon in the Mu Us Sandy Land influenced by the climate vicissitudes in northern hemisphere during glacial and interglacial periods since 150 ka BP.
文摘Milanggouwan stratigraphical section" named lately takes down 27 cycles of alternately evolutionary histories of desert depositions in the Mu Us area with the fluviolacustrine facies and palaeosols since 150 ka B.P. Studies show that the sedimentary form was induced by the growth and decline and confrontation each other between the winter monsoon and the summer monsoon of East Asia in the past 150 ka.
文摘Erectile dysfunction(ED)is increasing in prevalence,with estimates that 50%of men between 40 and 70 years of age suffer from the disease.Due to a wide array of available medical interventions,significant focus has been put on combination therapies that can treat ED refractory to first-line treatments such as phosphodiesterase 5 inhibitors(PDE5is).However,reviews evaluating monotherapy noninferiority and patient satisfaction of monotherapy versus combination therapy are lacking.A thorough PubMed search was performed to evaluate combination therapy in ED treatment.Articles published between January 2008 and June 2023 were reviewed,including randomized control trials,retrospective analyses,and cohort studies.Combination therapies included PDE5i plus another PDE5i,testosterone supplementation,α-blockers,vacuum erectile devices,intracavernosal injections,and low-intensity shockwave therapy.Based on this review,PDE5i monotherapy is not inferior to combination therapy and has increased satisfaction,convenience,and ease of use for patients with ED.Limitations of current literature on combination therapy include small sample size,limited data on patient satisfaction,possible biases,and limited follow-up time.Further studies will need larger randomized control trials with follow-up times greater than 1 year.
基金supported by the National Key Research and Development Program of China(2018YFC0604102)the project of China Geological Survey(DD20190015)。
文摘The Jiama porphyry copper deposit in Tibet is one of the proven supergiant copper deposits in the Qinghai-Tibet Plateau at present,with the reserves of geological resources equivalent to nearly 20×10^(6) t.However,it features wavy and steep terrain,leading to extremely difficult field operation and heavy interference.This study attempts to determine the effects of the tensor controlled-source audiomagnetotellurics(CSAMT)with high-power orthogonal signal sources(also referred to as the high-power tensor CSAMT)when it is applied to the deep geophysical exploration in plateaus with complex terrain and mining areas with strong interference.The test results show that the high current provided by the highpower tensor CSAMT not only greatly improved the signal-to-noise ratio but also guaranteed that effective signals were received in the case of a long transmitter-receiver distance.Meanwhile,the tensor data better described the anisotropy of deep geologic bodies.In addition,the tests also show that when the transmitting current reaches 60 A,it is still guaranteed that strong enough signals can be received in the case of the transmitter-receiver distance of about 25 km,sounding curves show no near field effect,and effective exploration depth can reach 3 km.The 2D inversion results are roughly consistent with drilling results,indicating that the high-power tensor CSAMT can be used to achieve nearly actual characteristics of underground electrical structures.Therefore,this method has great potential for application in deep geophysical exploration in plateaus and mining areas with complex terrain and strong interference,respectively.This study not only serves as important guidance on the prospecting in the Qinghai-Tibet Plateau but also can be used as positive references for deep mineral exploration in other areas.
