A new diterpene with an abietane skeleton, 3β-hydroxy-8α,14α-epoxyabieta-11,13(15)- dien-16,12-olide, was isolated from the root of Suregada glomerulate(Blume) Baill. Its structure was elucidated on the basis of sp...A new diterpene with an abietane skeleton, 3β-hydroxy-8α,14α-epoxyabieta-11,13(15)- dien-16,12-olide, was isolated from the root of Suregada glomerulate(Blume) Baill. Its structure was elucidated on the basis of spectroscopic and X-ray crystallographic analysis.展开更多
Two new diterpenoids,3,4,18β-cyclopropa-ent-abieta-8（14）,13（15）-dien-16,12-olide（1） and 3-oxojolkinolide B（2）,were isolated from the roots of Suregada glomerulata（Blume） Baill.Their structures were determin...Two new diterpenoids,3,4,18β-cyclopropa-ent-abieta-8（14）,13（15）-dien-16,12-olide（1） and 3-oxojolkinolide B（2）,were isolated from the roots of Suregada glomerulata（Blume） Baill.Their structures were determined by spectroscopic evidences. Compound 2 showed moderate cytotoxicity.展开更多
As a part of our interest in biologically active germacranolides from the genus Carpesium （Compositae）, we have investigated the constituents of Carpesium cernuum. This paper reports the isolation and structural elu...As a part of our interest in biologically active germacranolides from the genus Carpesium （Compositae）, we have investigated the constituents of Carpesium cernuum. This paper reports the isolation and structural elucidation of a new germacranolide, cernolide A （Compound 1）, from the herb. The structure of Compound 1 was determined as 2α,3β-dihydroxy-9-angeloxygermacra-4-en-6,12-olide on the basis of spectral evidence. The skeleton of Compound 1 was elucidation by IR, MS, ^1H and ^13C NMR, COSY, HMQC and HMBC experiments. The stereochemistry of Compound 1 was deduced by ROESY spectral data. Finally, the procedures of extraction and isolation were described in detail.展开更多
基金the Natural Science Foundation of Beijing(No.2042020)for support of this research
文摘A new diterpene with an abietane skeleton, 3β-hydroxy-8α,14α-epoxyabieta-11,13(15)- dien-16,12-olide, was isolated from the root of Suregada glomerulate(Blume) Baill. Its structure was elucidated on the basis of spectroscopic and X-ray crystallographic analysis.
基金the National Science and Technology Project of China(No.2009ZX09301-003-12-1) for financial support of this work
文摘Two new diterpenoids,3,4,18β-cyclopropa-ent-abieta-8（14）,13（15）-dien-16,12-olide（1） and 3-oxojolkinolide B（2）,were isolated from the roots of Suregada glomerulata（Blume） Baill.Their structures were determined by spectroscopic evidences. Compound 2 showed moderate cytotoxicity.
文摘As a part of our interest in biologically active germacranolides from the genus Carpesium （Compositae）, we have investigated the constituents of Carpesium cernuum. This paper reports the isolation and structural elucidation of a new germacranolide, cernolide A （Compound 1）, from the herb. The structure of Compound 1 was determined as 2α,3β-dihydroxy-9-angeloxygermacra-4-en-6,12-olide on the basis of spectral evidence. The skeleton of Compound 1 was elucidation by IR, MS, ^1H and ^13C NMR, COSY, HMQC and HMBC experiments. The stereochemistry of Compound 1 was deduced by ROESY spectral data. Finally, the procedures of extraction and isolation were described in detail.
