AIM： To determine prevalence of H pylori infection in symptomatic children in Buenos Aires, Argentina, and to investigate factors associated with HpyloH positivity. METHODS： A total of 395 children with upper gastro...AIM： To determine prevalence of H pylori infection in symptomatic children in Buenos Aires, Argentina, and to investigate factors associated with HpyloH positivity. METHODS： A total of 395 children with upper gastrointestinal symptoms referred to the Gastroenterology Unit of the Children Hospital ＂Sor Maria Ludovica＂ were evaluated for the presence of H py/or/by the ^13C-Urea Breath Test （^13C-UBT）. A questionnaire was applied to the recruited population. RESULTS： Prevalence of H pylo H infection was 40.0% in this population （mean age 9.97 ± 3.1 years）. The factors associated with H py/or/positivity were number of siblings （P 〈 0.001）, presence of pet cats （P = 0.03） and birds （P = 0.04） in the household, and antecedents of gastritis among family members （P = 0.01）. After multivariate analysis, number of siblings [Odds ratio （OR） = 1.39; 95% CI, 1.20-1.61] and contact with pet cats （OR = 1.76; 95% CI, 1.00-3.09） remained as variables associated with H pylori infection. CONCLUSION： The prevalence of H pylori infection in children with upper gastrointestinal symptoms in Argentina was similar to that reported in developed countries. Children from families with a higher crowding index and presence of pet cats have a higher risk of being colonized with Hpylori.展开更多
基金Supported by ARCAL LIV-6042 Project from the InternationalAtomic Energy Agency (IAEA), Vienna, Austria, UBACYTB077 Project from the University of Buenos Aires, Argentina,PICT 14243 Project from the National Agency of Scientifi c andTechnological Research, Argentina, and Project 2002-013 fromthe Thraser Research Fundation
文摘AIM： To determine prevalence of H pylori infection in symptomatic children in Buenos Aires, Argentina, and to investigate factors associated with HpyloH positivity. METHODS： A total of 395 children with upper gastrointestinal symptoms referred to the Gastroenterology Unit of the Children Hospital ＂Sor Maria Ludovica＂ were evaluated for the presence of H py/or/by the ^13C-Urea Breath Test （^13C-UBT）. A questionnaire was applied to the recruited population. RESULTS： Prevalence of H pylo H infection was 40.0% in this population （mean age 9.97 ± 3.1 years）. The factors associated with H py/or/positivity were number of siblings （P 〈 0.001）, presence of pet cats （P = 0.03） and birds （P = 0.04） in the household, and antecedents of gastritis among family members （P = 0.01）. After multivariate analysis, number of siblings [Odds ratio （OR） = 1.39; 95% CI, 1.20-1.61] and contact with pet cats （OR = 1.76; 95% CI, 1.00-3.09） remained as variables associated with H pylori infection. CONCLUSION： The prevalence of H pylori infection in children with upper gastrointestinal symptoms in Argentina was similar to that reported in developed countries. Children from families with a higher crowding index and presence of pet cats have a higher risk of being colonized with Hpylori.
