Kinetics of the coordination reaction of tetrakis(Ncarbomethoxymethyl3pyridyl) porphyrin(abbr. H2TβNACMSPyP) with Cu?ion has been studied in ophthalic acid buffer system in an ionic strength of 0.5mol...Kinetics of the coordination reaction of tetrakis(Ncarbomethoxymethyl3pyridyl) porphyrin(abbr. H2TβNACMSPyP) with Cu?ion has been studied in ophthalic acid buffer system in an ionic strength of 0.5mol·dm-3(KCI) at 35.0±0.1℃.The reaction is catalyzed by ophthalic ion. The effect of concentration of the catalyst, metal ion and pH value of solution was discussed. The kinetics equation of the reaction were obtained as d/dt=16.15{(1.0+3.35×1052)/1.0+1.57×10-42}T. The mechanism of the reaction was proposed. The deformation of the ring of porphyrins is the general condition in the reaction. Keyowrds:展开更多
以间三氟甲基苯胺(Ⅰ)作为原料,通过与氯甲酸-2-氯乙酯进行选择性的单酰胺化反应(Ⅱ)后,再在氢氧化钠水溶液中经水解重排反应,合成了间三氟甲基-N-羟乙基苯胺(Ⅲ),产物结构经1 H NMR,MS和IR表征.考察了反应溶剂、NaOH用量、反应温度和...以间三氟甲基苯胺(Ⅰ)作为原料,通过与氯甲酸-2-氯乙酯进行选择性的单酰胺化反应(Ⅱ)后,再在氢氧化钠水溶液中经水解重排反应,合成了间三氟甲基-N-羟乙基苯胺(Ⅲ),产物结构经1 H NMR,MS和IR表征.考察了反应溶剂、NaOH用量、反应温度和反应时间对产物收率的影响,实验结果得到:酰胺化反应以二氧六环为溶剂,反应时间3h,反应温度70℃;第二步(Ⅱ)水解重排反应的适宜反应条件为n(间三氟甲基苯胺)∶n(NaOH)=1∶6,反应温度为70℃,反应时间为5h,Ⅲ的总收率可达61%.展开更多
文摘Kinetics of the coordination reaction of tetrakis(Ncarbomethoxymethyl3pyridyl) porphyrin(abbr. H2TβNACMSPyP) with Cu?ion has been studied in ophthalic acid buffer system in an ionic strength of 0.5mol·dm-3(KCI) at 35.0±0.1℃.The reaction is catalyzed by ophthalic ion. The effect of concentration of the catalyst, metal ion and pH value of solution was discussed. The kinetics equation of the reaction were obtained as d/dt=16.15{(1.0+3.35×1052)/1.0+1.57×10-42}T. The mechanism of the reaction was proposed. The deformation of the ring of porphyrins is the general condition in the reaction. Keyowrds:
文摘以间三氟甲基苯胺(Ⅰ)作为原料,通过与氯甲酸-2-氯乙酯进行选择性的单酰胺化反应(Ⅱ)后,再在氢氧化钠水溶液中经水解重排反应,合成了间三氟甲基-N-羟乙基苯胺(Ⅲ),产物结构经1 H NMR,MS和IR表征.考察了反应溶剂、NaOH用量、反应温度和反应时间对产物收率的影响,实验结果得到:酰胺化反应以二氧六环为溶剂,反应时间3h,反应温度70℃;第二步(Ⅱ)水解重排反应的适宜反应条件为n(间三氟甲基苯胺)∶n(NaOH)=1∶6,反应温度为70℃,反应时间为5h,Ⅲ的总收率可达61%.
基金supported by the National Natural Science Foundation of China(21002006,20452002)Special Program for Key Basic Research of the Ministry of Science and Technology,China(2004-973-36)~~
