The interaction of ruthenium polypyridyl complex with DNA has been studied by isothermal titration calorimetry (ITC). The results show that complex [Ru(phen)2PMIP]2+ {phen=1,10-phenanthroline, PMIP=2-(4-methylphenyl)i...The interaction of ruthenium polypyridyl complex with DNA has been studied by isothermal titration calorimetry (ITC). The results show that complex [Ru(phen)2PMIP]2+ {phen=1,10-phenanthroline, PMIP=2-(4-methylphenyl)imidazo1,10-phenanthroline} interacts with calf thymus DNA (CT DNA) in terms of a model for a single set of identical sites through intercalation. The results are in agreement with our previous observations from spectroscopic methods and viscosity measurements. In addition, the results further show that the driving force for DNA binding with the complex is mainly driven by the enthalpy changes, and the contribution from the entropy changes to this driving force is negligible.展开更多
以钌（Ⅱ）多吡啶配合物[Ru（bipy）2DAFND]（Cl O4）2（Ru-DAFND,bipy=2,2＇-联吡啶,DAFND=4,5-二氮杂芴-9-对硝基苯腙）为指示剂,采用锁相放大技术构建了基于荧光猝灭原理的光纤DNA传感器,研究了传感器的性能。以p H 7.1的Tris缓冲溶...以钌（Ⅱ）多吡啶配合物[Ru（bipy）2DAFND]（Cl O4）2（Ru-DAFND,bipy=2,2＇-联吡啶,DAFND=4,5-二氮杂芴-9-对硝基苯腙）为指示剂,采用锁相放大技术构建了基于荧光猝灭原理的光纤DNA传感器,研究了传感器的性能。以p H 7.1的Tris缓冲溶液为介质,在2.6×10-8~5.4×10-6mol/L范围,ct DNA浓度与传感器光学敏感膜的相对滞后相移（Δφ）有较好的线性关系,检出限为8.4×10-9mol/L,响应时间为70 s。通过研究溶液p H值和干扰物对传感器性能的影响,表明该传感系统具有较好的重复性和稳定性。展开更多
Catalysis under irradiation by visible light has become a highly dynamic and promising research area in chemical sciences. Such catalysis primarily entails photoinduced electron- and energy-transfer chemistry sensitiz...Catalysis under irradiation by visible light has become a highly dynamic and promising research area in chemical sciences. Such catalysis primarily entails photoinduced electron- and energy-transfer chemistry sensitized by polypyridyl complexes, organic dyes, and heterogeneous catalysts. Remarkably though, while the electrochemical and photophysical properties of these catalysts have been extensively studied, only recently has the chemical commu- nity begun to appreciate the great potential of the utilization of visible-light photocatalysis as a broadly useful method- ology to advanced organic synthesis. Since 2008, visible- light photocatalysis has witnessed a rapid development as a possible alternative to strong oxidizing and reducing agents and radical-initiating reagents. Due to the relative obscurity of photoredox catalysis in organic synthesis, the primary focus of this thematic issue will be centered on modem photocatalysis, especially in the context of photo-driven electron- and energy-transfer catalysis.展开更多
文摘The interaction of ruthenium polypyridyl complex with DNA has been studied by isothermal titration calorimetry (ITC). The results show that complex [Ru(phen)2PMIP]2+ {phen=1,10-phenanthroline, PMIP=2-(4-methylphenyl)imidazo1,10-phenanthroline} interacts with calf thymus DNA (CT DNA) in terms of a model for a single set of identical sites through intercalation. The results are in agreement with our previous observations from spectroscopic methods and viscosity measurements. In addition, the results further show that the driving force for DNA binding with the complex is mainly driven by the enthalpy changes, and the contribution from the entropy changes to this driving force is negligible.
文摘Catalysis under irradiation by visible light has become a highly dynamic and promising research area in chemical sciences. Such catalysis primarily entails photoinduced electron- and energy-transfer chemistry sensitized by polypyridyl complexes, organic dyes, and heterogeneous catalysts. Remarkably though, while the electrochemical and photophysical properties of these catalysts have been extensively studied, only recently has the chemical commu- nity begun to appreciate the great potential of the utilization of visible-light photocatalysis as a broadly useful method- ology to advanced organic synthesis. Since 2008, visible- light photocatalysis has witnessed a rapid development as a possible alternative to strong oxidizing and reducing agents and radical-initiating reagents. Due to the relative obscurity of photoredox catalysis in organic synthesis, the primary focus of this thematic issue will be centered on modem photocatalysis, especially in the context of photo-driven electron- and energy-transfer catalysis.
