A review to comment the inter relationship between the consumtive causes and pathogenesis of mitochondrial energy defects in some important types of neurodegenerative diseases,such as Parkinson’s disease, Alzheimer’...A review to comment the inter relationship between the consumtive causes and pathogenesis of mitochondrial energy defects in some important types of neurodegenerative diseases,such as Parkinson’s disease, Alzheimer’s disease, Huntington’s disease and others. The crucial roles of permeability transition pores of mitochondrial membranes were emphasized and certain routes of therapeutic trials to reverse the mitochondrial defect were discussed.展开更多
文摘A review to comment the inter relationship between the consumtive causes and pathogenesis of mitochondrial energy defects in some important types of neurodegenerative diseases,such as Parkinson’s disease, Alzheimer’s disease, Huntington’s disease and others. The crucial roles of permeability transition pores of mitochondrial membranes were emphasized and certain routes of therapeutic trials to reverse the mitochondrial defect were discussed.
