Fentanyl,a synthetic opioid,is a popular choice amongst anesthesiologists because of its intense analgesia,cardiovascular stability and low histamine release.Reflex cough is often observed after an iv bolus of fentany...Fentanyl,a synthetic opioid,is a popular choice amongst anesthesiologists because of its intense analgesia,cardiovascular stability and low histamine release.Reflex cough is often observed after an iv bolus of fentanyl during induction.Yet this phenomenon may be undesirable in patients with some co-existing diseases including increased intracranial pressure,open eye injury,dissecting aortic aneurysm,pneumothorax or reactive airway disease.The purpose of this paper is to review the mechanism,influential factors and prevention of cough reflex induced by fentanyl in recent years.展开更多
文摘Fentanyl,a synthetic opioid,is a popular choice amongst anesthesiologists because of its intense analgesia,cardiovascular stability and low histamine release.Reflex cough is often observed after an iv bolus of fentanyl during induction.Yet this phenomenon may be undesirable in patients with some co-existing diseases including increased intracranial pressure,open eye injury,dissecting aortic aneurysm,pneumothorax or reactive airway disease.The purpose of this paper is to review the mechanism,influential factors and prevention of cough reflex induced by fentanyl in recent years.
