[目的]系统评价平衡训练对老年人跌倒发生及平衡功能的影响。[方法]计算机检索PubMed、Web of Science、Cochrane Library、EMbase、EBSCO、知网、万方、维普等中英文数据库,收集平衡训练干预老年人的随机对照试验,采用Revman5.1.0软件...[目的]系统评价平衡训练对老年人跌倒发生及平衡功能的影响。[方法]计算机检索PubMed、Web of Science、Cochrane Library、EMbase、EBSCO、知网、万方、维普等中英文数据库,收集平衡训练干预老年人的随机对照试验,采用Revman5.1.0软件进行数据分析。[结果]共纳入10个随机对照试验,共1 990例病人;结果显示:应用平衡训练的干预组发生跌倒的人数明显低于对照组[RR=0.74,95%CI(0.60,0.90),P=0.003],平衡训练对改善平衡功能效果显著[SMD=0.38,95%CI(0.14,0.63),P=0.002],且干预组起立行走时间测试用时更少[MD=-4.51,95%CI=(-6.34,-2.67),P<0.000 01],但对跌倒风险效果无统计学意义[MD=-15.60,95%CI=(-40.58,9.39),P=0.22]。[结论]平衡训练可有效减少老年人跌倒的发生,并可改善老年人的平衡功能。展开更多
PURPOSE: To investigate the associations of measures of frailty to prevalent age-related maculopathy (ARM). DESIGN: Cross-sectional population-based study. METHODS: Time to walk a measured course (gait-time), handgrip...PURPOSE: To investigate the associations of measures of frailty to prevalent age-related maculopathy (ARM). DESIGN: Cross-sectional population-based study. METHODS: Time to walk a measured course (gait-time), handgrip strength, peak expiratory flow rate, ability to stand from a sitting position without using arms, self-reported co-morbidities, and ARM were assessed at the third examination of the Beaver Dam Eye Study (n=2,962). ARM was determined by grading stereoscopic color fundus photographs. RESULTS: While controlling for age, smoking, and the number of co-morbid conditions, weaker handgrip strength was associated with early ARM (odds ratio [OR]10 kg decrease 1.28, confidence interval [CI]1.08, 1.52, P = .004) and late ARM(OR 1.55, 95% CI 1.02, 2.36) in men but not women. Othermeasures of frailty were not related to ARM. CONCLUSIONS: A weak cross-sectional association of handgrip strength with ARM (in men) was found after controlling for co-morbid conditions. These data suggest that ARM is due to a specific disease process, albeit age-related, rather than to biologic aging, as reflected by measures of frailty.展开更多
文摘PURPOSE: To investigate the associations of measures of frailty to prevalent age-related maculopathy (ARM). DESIGN: Cross-sectional population-based study. METHODS: Time to walk a measured course (gait-time), handgrip strength, peak expiratory flow rate, ability to stand from a sitting position without using arms, self-reported co-morbidities, and ARM were assessed at the third examination of the Beaver Dam Eye Study (n=2,962). ARM was determined by grading stereoscopic color fundus photographs. RESULTS: While controlling for age, smoking, and the number of co-morbid conditions, weaker handgrip strength was associated with early ARM (odds ratio [OR]10 kg decrease 1.28, confidence interval [CI]1.08, 1.52, P = .004) and late ARM(OR 1.55, 95% CI 1.02, 2.36) in men but not women. Othermeasures of frailty were not related to ARM. CONCLUSIONS: A weak cross-sectional association of handgrip strength with ARM (in men) was found after controlling for co-morbid conditions. These data suggest that ARM is due to a specific disease process, albeit age-related, rather than to biologic aging, as reflected by measures of frailty.