目的研究自体虹膜色素上皮细胞(Iris P igm ent Ep ithelium,IPE)移植治疗视网膜色素上皮细胞变性的效果。方法采用酶—机械分离—酶消化法法获取高纯度、高活力的RPE细胞用于移植,采用外路法将IPE细胞悬液移植入视网膜下腔。结果IPE移...目的研究自体虹膜色素上皮细胞(Iris P igm ent Ep ithelium,IPE)移植治疗视网膜色素上皮细胞变性的效果。方法采用酶—机械分离—酶消化法法获取高纯度、高活力的RPE细胞用于移植,采用外路法将IPE细胞悬液移植入视网膜下腔。结果IPE移植术后患者眼底移植区色素沉着减少,未见渗出,出血,视网膜平,视力从入院时的0.15提高至术后2W的0.2。多焦ERG显示移植区P1波平均反应密度上升。结论IPE细胞移植有望成为RP治疗的一新方法。展开更多
Purpose:To describe the use of ultrasound biomicroscopy(UBM)to image retained nuclear fragments posterior to the iris plane after uncomplicated phacoemulsification with posterior chamber intraocular lens(PCIOL)implant...Purpose:To describe the use of ultrasound biomicroscopy(UBM)to image retained nuclear fragments posterior to the iris plane after uncomplicated phacoemulsification with posterior chamber intraocular lens(PCIOL)implantation in two patients.Design:Interventional case report.Methods:Two patients presented with an iris elevation after uncomplicated phacoemulsification and lens implantation.Results:Visual acuity was 20/20 in the first patient and 20/30 in the second.There was no anterior chamber inflammation in either eye.UBM revealed a small,retained nuclear fragment between the iris pigment epithelium and the anterior lens capsule,causing localized anterior iris displacement in both patients.The PCIOL was within the capsular bag,and the iris root and ciliary body were normal in both patients.Conclusion:UBM can demonstrate retained lens fragments within the posterior chamber.展开更多
文摘目的研究自体虹膜色素上皮细胞(Iris P igm ent Ep ithelium,IPE)移植治疗视网膜色素上皮细胞变性的效果。方法采用酶—机械分离—酶消化法法获取高纯度、高活力的RPE细胞用于移植,采用外路法将IPE细胞悬液移植入视网膜下腔。结果IPE移植术后患者眼底移植区色素沉着减少,未见渗出,出血,视网膜平,视力从入院时的0.15提高至术后2W的0.2。多焦ERG显示移植区P1波平均反应密度上升。结论IPE细胞移植有望成为RP治疗的一新方法。
文摘Purpose:To describe the use of ultrasound biomicroscopy(UBM)to image retained nuclear fragments posterior to the iris plane after uncomplicated phacoemulsification with posterior chamber intraocular lens(PCIOL)implantation in two patients.Design:Interventional case report.Methods:Two patients presented with an iris elevation after uncomplicated phacoemulsification and lens implantation.Results:Visual acuity was 20/20 in the first patient and 20/30 in the second.There was no anterior chamber inflammation in either eye.UBM revealed a small,retained nuclear fragment between the iris pigment epithelium and the anterior lens capsule,causing localized anterior iris displacement in both patients.The PCIOL was within the capsular bag,and the iris root and ciliary body were normal in both patients.Conclusion:UBM can demonstrate retained lens fragments within the posterior chamber.