Purpose:To determine whether intracameral bevacizumab decreases vascular leakage from iris rubeosis in patients with neovascular glaucoma.Design:Interventional case series.Methods:The study included six eyes of three ...Purpose:To determine whether intracameral bevacizumab decreases vascular leakage from iris rubeosis in patients with neovascular glaucoma.Design:Interventional case series.Methods:The study included six eyes of three patients with secondary neovascular glaucoma due to proliferative diabetic retinopathy(n=2)or ischemic central retinal vein occlusion(n=1).All patients received an intracameral injection of 1.0 mg bevacizumab.Morphologic changes and vascular leakage were investigated prospectively by iris fluorescein angiography.Results:Decrease in leakage was detected as early as one day after injection.No inflammation was observed.No relapse was seen within the follow-up of four weeks.Conclusion:Intraocular injection of bevacizumab may provide an additional strategy for the treatment of iris rubeosis in neovascular glaucoma.展开更多
To report in four patients with retinal vein occlusion the presence of biomicr oscopically visible circulation in the minor arterial circle of the iris, preced ing rubeosis iridis in two cases. Retrospective observati...To report in four patients with retinal vein occlusion the presence of biomicr oscopically visible circulation in the minor arterial circle of the iris, preced ing rubeosis iridis in two cases. Retrospective observational case series. Four patients with ischemic type of central or hemi-central retinal vein occlusion s een at a single center. Dilation of the minor arterial circle remnants with biom icroscopically visible circulation was observed in four eyes of four adult patie nts with severe retinal ischemia secondary to retinal vein occlusion and precede d the occurrence of anterior segment neovascularization in two cases. In patient s with ischemic retinal vein occlusion, the clinical finding of a dilation of th e minor arterial circle may indicate the necessity of a closer follow-up to mak e a timely decision on panretinal photocoagulation.展开更多
文摘Purpose:To determine whether intracameral bevacizumab decreases vascular leakage from iris rubeosis in patients with neovascular glaucoma.Design:Interventional case series.Methods:The study included six eyes of three patients with secondary neovascular glaucoma due to proliferative diabetic retinopathy(n=2)or ischemic central retinal vein occlusion(n=1).All patients received an intracameral injection of 1.0 mg bevacizumab.Morphologic changes and vascular leakage were investigated prospectively by iris fluorescein angiography.Results:Decrease in leakage was detected as early as one day after injection.No inflammation was observed.No relapse was seen within the follow-up of four weeks.Conclusion:Intraocular injection of bevacizumab may provide an additional strategy for the treatment of iris rubeosis in neovascular glaucoma.
文摘To report in four patients with retinal vein occlusion the presence of biomicr oscopically visible circulation in the minor arterial circle of the iris, preced ing rubeosis iridis in two cases. Retrospective observational case series. Four patients with ischemic type of central or hemi-central retinal vein occlusion s een at a single center. Dilation of the minor arterial circle remnants with biom icroscopically visible circulation was observed in four eyes of four adult patie nts with severe retinal ischemia secondary to retinal vein occlusion and precede d the occurrence of anterior segment neovascularization in two cases. In patient s with ischemic retinal vein occlusion, the clinical finding of a dilation of th e minor arterial circle may indicate the necessity of a closer follow-up to mak e a timely decision on panretinal photocoagulation.
