Objective To develop a nationally acceptable blood pressure(BP)reference standards for the diagnosis and evaluation of hypertension in children and adolescents in China.Methods The current study was based on the data ...Objective To develop a nationally acceptable blood pressure(BP)reference standards for the diagnosis and evaluation of hypertension in children and adolescents in China.Methods The current study was based on the data from eleven large-scale cross-sectional BP surveys in China's Mainland since 2001,the survey sites were representative of national geographical distribution including four municipalities(Beijing,Shanghai,Tianjin,Chongqing)and seven provinces(Hunan,Liaoning,Hebei,Zhejiang,Guangxi,Xinqiang and Guangdong).The surveys which met the following selection criteria were involved to form the reference population sample and pooled database:1)Subjects were Han nationality and their ages were from 3 to 18 years old;2)BP levels were measured by auscultation using standard sphygmomanometer and recorded as Korotkoff phase 1(SBP),Korotkoff phase 4(DBP-K4)and/or Korotkoff phase 5(DBP-K5);3)All surveyors were trained before investigations and standard quality control was implemented throughout the BP measuring process;4)Basic variables,except BPs,were at least included but not limited to age,sex,nationality,height and weight.Totally 112 227 subjects(56 912 males accounting for 50.7%)were enrolled in the reference population sample in this study.SPSS 13.0 software was used to do the descriptive statistical analysis.Centile curves for SBP,DBP-K4 and DBP-K5 were drawn by sex using LMS method.Z scores of Height and BMI were calculated based on the data from the Chinese National Survey on Constitution and Health(CNSCH)in schoolchildren in 2005 to evaluate the nutrition status and development level of the reference population.Results The reference population had an optimal representation of Chinese Han children and adolescents.The resulting curves provided specific cut off points based on age and sex for the diagnosis of high normal BP,hypertension and severe hypertension,respectively.Given the best approach for blood pressure measurement in children and adolescents remained controversial,especially on the choice of K4 or K5展开更多
1前言 我国已步入老龄社会,新近公布的第六次全国人口普查数据显示,≥60岁人口占13.26％,≥65岁人口占8.87％。随着人口老龄化的进展,我国老年人群高血压的患病率将增加。高血压是导致心脑血管疾病的主要危险因素,是全球范围内的重大公...1前言 我国已步入老龄社会,新近公布的第六次全国人口普查数据显示,≥60岁人口占13.26％,≥65岁人口占8.87％。随着人口老龄化的进展,我国老年人群高血压的患病率将增加。高血压是导致心脑血管疾病的主要危险因素,是全球范围内的重大公共卫生问题。大量流行病学及临床证据表明,高血压显著增加老年人发生缺血性心脏病、脑卒中、肾功能衰竭、主动脉与外周动脉疾病等靶器官损害的危险,是老年人群致死和致残的主要原因之一。在Framingham研究中,65～94岁人群中收缩压＞180 mmHg(1 mm Hg=0.133 kPa)者比＜120 mm Hg的个体冠心病危险高3倍。展开更多
文摘Objective To develop a nationally acceptable blood pressure(BP)reference standards for the diagnosis and evaluation of hypertension in children and adolescents in China.Methods The current study was based on the data from eleven large-scale cross-sectional BP surveys in China's Mainland since 2001,the survey sites were representative of national geographical distribution including four municipalities(Beijing,Shanghai,Tianjin,Chongqing)and seven provinces(Hunan,Liaoning,Hebei,Zhejiang,Guangxi,Xinqiang and Guangdong).The surveys which met the following selection criteria were involved to form the reference population sample and pooled database:1)Subjects were Han nationality and their ages were from 3 to 18 years old;2)BP levels were measured by auscultation using standard sphygmomanometer and recorded as Korotkoff phase 1(SBP),Korotkoff phase 4(DBP-K4)and/or Korotkoff phase 5(DBP-K5);3)All surveyors were trained before investigations and standard quality control was implemented throughout the BP measuring process;4)Basic variables,except BPs,were at least included but not limited to age,sex,nationality,height and weight.Totally 112 227 subjects(56 912 males accounting for 50.7%)were enrolled in the reference population sample in this study.SPSS 13.0 software was used to do the descriptive statistical analysis.Centile curves for SBP,DBP-K4 and DBP-K5 were drawn by sex using LMS method.Z scores of Height and BMI were calculated based on the data from the Chinese National Survey on Constitution and Health(CNSCH)in schoolchildren in 2005 to evaluate the nutrition status and development level of the reference population.Results The reference population had an optimal representation of Chinese Han children and adolescents.The resulting curves provided specific cut off points based on age and sex for the diagnosis of high normal BP,hypertension and severe hypertension,respectively.Given the best approach for blood pressure measurement in children and adolescents remained controversial,especially on the choice of K4 or K5
文摘1前言 我国已步入老龄社会,新近公布的第六次全国人口普查数据显示,≥60岁人口占13.26％,≥65岁人口占8.87％。随着人口老龄化的进展,我国老年人群高血压的患病率将增加。高血压是导致心脑血管疾病的主要危险因素,是全球范围内的重大公共卫生问题。大量流行病学及临床证据表明,高血压显著增加老年人发生缺血性心脏病、脑卒中、肾功能衰竭、主动脉与外周动脉疾病等靶器官损害的危险,是老年人群致死和致残的主要原因之一。在Framingham研究中,65～94岁人群中收缩压＞180 mmHg(1 mm Hg=0.133 kPa)者比＜120 mm Hg的个体冠心病危险高3倍。
