肝硬化腹水（ascites due to cirrhosis）是肝硬化失代偿的主要表现之一，严重影响患者劳动能力和生活质量。中医药治疗在促进腹水消退、预防腹水复发等方面具有重要作用。我们在参考欧洲肝病学会《肝硬化腹水、自发性细菌性腹膜炎、肝...肝硬化腹水（ascites due to cirrhosis）是肝硬化失代偿的主要表现之一，严重影响患者劳动能力和生活质量。中医药治疗在促进腹水消退、预防腹水复发等方面具有重要作用。我们在参考欧洲肝病学会《肝硬化腹水、自发性细菌性腹膜炎、肝肾综合征临床实践指南》、美国肝病学会《成人肝硬化腹水处理意见》的基础上，依据循证医学原则，通过对肝硬化腹水文献检索及相关指南的复习。展开更多
Since its initial description in 1964,research hastransformed spontaneous bacterial peritonitis (SBP)from a feared disease (with reported mortality of 90%)to a treatable complication of decompensated cirrhosis,albeit ...Since its initial description in 1964,research hastransformed spontaneous bacterial peritonitis (SBP)from a feared disease (with reported mortality of 90%)to a treatable complication of decompensated cirrhosis,albeit with steady prevalence and a high recurrencerate. Bacterial translocation,the key mechanism in thepathogenesis of SBP,is only possible because of theconcurrent failure of defensive mechanisms in cirrhosis.Variants of SBP should be treated. Leucocyte esterasereagent strips have managed to shorten the 'tap-to-shot' time,while future studies should look into theircombined use with ascitic fluid pH. Third generationcephalosporins are the antibiotic of choice becausethey have a number of advantages. Renal dysfunctionhas been shown to be an independent predictor ofmortality in patients with SBP. Albumin is felt to reducethe risk of renal impairment by improving effectiveintravascular volume,and by helping to bind pro-inflammatory molecules. Following a single episodeof SBP,patients should have long-term antibioticprophylaxis and be considered for liver transplantation.展开更多
文摘肝硬化腹水（ascites due to cirrhosis）是肝硬化失代偿的主要表现之一，严重影响患者劳动能力和生活质量。中医药治疗在促进腹水消退、预防腹水复发等方面具有重要作用。我们在参考欧洲肝病学会《肝硬化腹水、自发性细菌性腹膜炎、肝肾综合征临床实践指南》、美国肝病学会《成人肝硬化腹水处理意见》的基础上，依据循证医学原则，通过对肝硬化腹水文献检索及相关指南的复习。
文摘Since its initial description in 1964,research hastransformed spontaneous bacterial peritonitis (SBP)from a feared disease (with reported mortality of 90%)to a treatable complication of decompensated cirrhosis,albeit with steady prevalence and a high recurrencerate. Bacterial translocation,the key mechanism in thepathogenesis of SBP,is only possible because of theconcurrent failure of defensive mechanisms in cirrhosis.Variants of SBP should be treated. Leucocyte esterasereagent strips have managed to shorten the 'tap-to-shot' time,while future studies should look into theircombined use with ascitic fluid pH. Third generationcephalosporins are the antibiotic of choice becausethey have a number of advantages. Renal dysfunctionhas been shown to be an independent predictor ofmortality in patients with SBP. Albumin is felt to reducethe risk of renal impairment by improving effectiveintravascular volume,and by helping to bind pro-inflammatory molecules. Following a single episodeof SBP,patients should have long-term antibioticprophylaxis and be considered for liver transplantation.
