目的:探讨在胰胆管疾病中,分别使用2D磁共振胰胆管成像(MRCP)与3D MRCP的成像效果。方法:选取50例胰胆管疾病患者为研究对象,患者均行M R C P检查,并进行2D、3D成像,对比不同成像方式获取的图像效果。结果:2D MRCP获取的图像优良率为98....目的:探讨在胰胆管疾病中,分别使用2D磁共振胰胆管成像(MRCP)与3D MRCP的成像效果。方法:选取50例胰胆管疾病患者为研究对象,患者均行M R C P检查,并进行2D、3D成像,对比不同成像方式获取的图像效果。结果:2D MRCP获取的图像优良率为98.00%,明显高于3D MRCP 88.00%的优良率,差异有统计学意义(P<0.05);在图像显示情况上,2D序列在伪影上明显少于3D序列(P<0.05);在胰胆管显示情况情况上,2D序列在肝内胆管与胰管的显示上高于层厚1.6mm的3D序列(P<0.05),但2D序列与层厚4mm的3D序列在肝内胆管显示上无显著差异(P>0.05);在肝总管、胆囊、胆囊管的显示上,2D与3D序列的显示上无显差异(P>0.05)。结论:在胰胆管疾病中,应用2D MRCP成像的质量明显高于3D MRCP成像,所以2D MRCP更适用于胆管系统疾病的检查。展开更多
AIM: The aim of this study was to describe an auxiliary combined liver-small bowel transplantation model with the preservation of duodenum, head of pancreas and hepatic biliary system in pigs. The technique, feasibili...AIM: The aim of this study was to describe an auxiliary combined liver-small bowel transplantation model with the preservation of duodenum, head of pancreas and hepatic biliary system in pigs. The technique, feasibility, security and immunosuppression were commented.METHODS- Forty outbred long-white pigs were randomized into two groups, and the auxiliary composite liver/small bowel allotransplantations were undertaken in 10 longwhite pigs in each group with the recipient liver preserved.Group A was not treated with immunosuppressive drugs while group B was treated with cyclosporine A and methylprednisolone after operation. The hemodynamic changes and amylase of body fluid (including blood, urine and abdominal drain) were analyzed.RESULTS: The average survival time of the animals was 10±1.929 d (6 to 25 d) in group A while more than 30 d in group B. The pigs could tolerate the hemodynamic fluctuation during operation and the hemodynamic parameters recovered to normal 2 h after blood reperfusion. The transient high amylase level was decreased to normal one week after operation and autopsy showed no pancreatitis.CONCLUSION: Auxiliary en-b/oc liver-small bowel transplantation with partial pancreas preservation is a feasible and safe model with simplified surgical techniques for composite liver/small bowel transplantation. This model may be used as a preclinical training model for clinical transplantation method, clinical liver-small bowel transplantation related complication research, basic research including immunosuppressive treatment, organ preservation, acute rejection, chronic rejection, immuno-tolerance and xenotransplantation.展开更多
文摘AIM: The aim of this study was to describe an auxiliary combined liver-small bowel transplantation model with the preservation of duodenum, head of pancreas and hepatic biliary system in pigs. The technique, feasibility, security and immunosuppression were commented.METHODS- Forty outbred long-white pigs were randomized into two groups, and the auxiliary composite liver/small bowel allotransplantations were undertaken in 10 longwhite pigs in each group with the recipient liver preserved.Group A was not treated with immunosuppressive drugs while group B was treated with cyclosporine A and methylprednisolone after operation. The hemodynamic changes and amylase of body fluid (including blood, urine and abdominal drain) were analyzed.RESULTS: The average survival time of the animals was 10±1.929 d (6 to 25 d) in group A while more than 30 d in group B. The pigs could tolerate the hemodynamic fluctuation during operation and the hemodynamic parameters recovered to normal 2 h after blood reperfusion. The transient high amylase level was decreased to normal one week after operation and autopsy showed no pancreatitis.CONCLUSION: Auxiliary en-b/oc liver-small bowel transplantation with partial pancreas preservation is a feasible and safe model with simplified surgical techniques for composite liver/small bowel transplantation. This model may be used as a preclinical training model for clinical transplantation method, clinical liver-small bowel transplantation related complication research, basic research including immunosuppressive treatment, organ preservation, acute rejection, chronic rejection, immuno-tolerance and xenotransplantation.
