AIM: To work out an indMdualized lipiodol dose in transcabheter arterial chemoembolization (TACE) for large hepatocellular carcinoma (HCC) according to its blood supply evaluated by CT.METHODS: One hundred patients wi...AIM: To work out an indMdualized lipiodol dose in transcabheter arterial chemoembolization (TACE) for large hepatocellular carcinoma (HCC) according to its blood supply evaluated by CT.METHODS: One hundred patients with large HCC (more than 8 cm in diameter) were studied by multidetector helical CT. Patterns of blood supply of HCC were divided into sufficient blood supply, poor blood supply, mixed blood supply and arteriovenous (A-V) shunt. The dose of ultrafluid lipiodol was determined by diameter and blood supply type of HCC. Patients were divided into two groups (50 cases each): lipiodol perfusion group and iodized oil perfusion group according to tumor diameter and the blood supply type of tumor.RESULTS: The confirmation and effective rates were 82%,84% in the first group and 36%, 46% in the second group (P<0.01).CONCLUSION: A relatively individualized lipiodol dose may be determined according to the blood supply pattern and the tumor diameter by CT imaging.展开更多
为了提高罂粟籽油的稳定性,通过复凝聚法制备罂粟籽油微囊。以阿拉伯胶和明胶为壁材,通过微囊化技术、喷雾干燥得到微囊。正交优化确定最佳配方,并考察芯壁比(罂粟籽油∶阿拉伯胶/明胶)对微囊包封率、载药量的影响。结果表明,罂粟籽油...为了提高罂粟籽油的稳定性,通过复凝聚法制备罂粟籽油微囊。以阿拉伯胶和明胶为壁材,通过微囊化技术、喷雾干燥得到微囊。正交优化确定最佳配方,并考察芯壁比(罂粟籽油∶阿拉伯胶/明胶)对微囊包封率、载药量的影响。结果表明,罂粟籽油微囊制备的最佳条件为:壁材浓度为2.0%,芯壁比1∶3,p H 4.2,乳化剂浓度1.5%,此时包封率为76.9%。包封后罂粟籽油的氧化实验表明微囊可提高其存储稳定性。复凝聚法制备罂粟籽油微囊的工艺简单,产品稳定性好,在食品工业中具有较好的应用前景。展开更多
文摘AIM: To work out an indMdualized lipiodol dose in transcabheter arterial chemoembolization (TACE) for large hepatocellular carcinoma (HCC) according to its blood supply evaluated by CT.METHODS: One hundred patients with large HCC (more than 8 cm in diameter) were studied by multidetector helical CT. Patterns of blood supply of HCC were divided into sufficient blood supply, poor blood supply, mixed blood supply and arteriovenous (A-V) shunt. The dose of ultrafluid lipiodol was determined by diameter and blood supply type of HCC. Patients were divided into two groups (50 cases each): lipiodol perfusion group and iodized oil perfusion group according to tumor diameter and the blood supply type of tumor.RESULTS: The confirmation and effective rates were 82%,84% in the first group and 36%, 46% in the second group (P<0.01).CONCLUSION: A relatively individualized lipiodol dose may be determined according to the blood supply pattern and the tumor diameter by CT imaging.
文摘为了提高罂粟籽油的稳定性,通过复凝聚法制备罂粟籽油微囊。以阿拉伯胶和明胶为壁材,通过微囊化技术、喷雾干燥得到微囊。正交优化确定最佳配方,并考察芯壁比(罂粟籽油∶阿拉伯胶/明胶)对微囊包封率、载药量的影响。结果表明,罂粟籽油微囊制备的最佳条件为:壁材浓度为2.0%,芯壁比1∶3,p H 4.2,乳化剂浓度1.5%,此时包封率为76.9%。包封后罂粟籽油的氧化实验表明微囊可提高其存储稳定性。复凝聚法制备罂粟籽油微囊的工艺简单,产品稳定性好,在食品工业中具有较好的应用前景。
