目的分析巨大胸膜孤立性纤维肿瘤(solitary fibrous tumor of the pleura,SFTP)的临床特征、治疗及预后。方法回顾性分析2000年1月至2015年6月间本院收治的10例巨大SFTP患者临床资料,包括术前检查、手术方式、组织病理学及随访。结果 1...目的分析巨大胸膜孤立性纤维肿瘤(solitary fibrous tumor of the pleura,SFTP)的临床特征、治疗及预后。方法回顾性分析2000年1月至2015年6月间本院收治的10例巨大SFTP患者临床资料,包括术前检查、手术方式、组织病理学及随访。结果 10例患者均行肿瘤切除,其中3例患者因肿瘤侵及肺组织并行肺楔形切除。术后病理均为胸膜孤立性纤维性瘤,其中良性肿瘤6例、低度恶性肿瘤4例,术后均未放疗和化疗。2例患者分别术后11个月、27个月复发及转移,均为恶性肿瘤,术后生存时间分别为23个月和32个月,其余患者均未复发及转移。结论 SFTP是一种少见间叶组织的肿瘤,手术切除是一种有效的治疗方法,预后良好。展开更多
A case of a successfully treated solitary fibrous tumor (SFT) of the liver is reported.An 82-year-old female presented with left upper abdominal discomfort,a firm mass on palpation,and imaging studies revealed a large...A case of a successfully treated solitary fibrous tumor (SFT) of the liver is reported.An 82-year-old female presented with left upper abdominal discomfort,a firm mass on palpation,and imaging studies revealed a large tumor,15 cm in diameter,arising from the left lobe of the liver.A formal left hepatectomy was performed.Microscopic evaluation showed spindle and fibroblast-like cells within the collagenous stroma.Immunohistochemistry disclosed diffuse CD34 and positive vimentin,supporting the diagnosis of a benign SFT.The patient remained well 21 months after surgery.SFT of the liver is a very rare neoplasm of mesenchymal origin.In most cases it is a benign lesion,although some may have malignant histological features and recur locally or metastasize.With less than 30 reported cases in the literature,little can be said regarding its natural history or the benefits of adjuvant radiochemotherapy.Complete surgical resection remains the cornerstone of its treatment.展开更多
文摘目的分析巨大胸膜孤立性纤维肿瘤(solitary fibrous tumor of the pleura,SFTP)的临床特征、治疗及预后。方法回顾性分析2000年1月至2015年6月间本院收治的10例巨大SFTP患者临床资料,包括术前检查、手术方式、组织病理学及随访。结果 10例患者均行肿瘤切除,其中3例患者因肿瘤侵及肺组织并行肺楔形切除。术后病理均为胸膜孤立性纤维性瘤,其中良性肿瘤6例、低度恶性肿瘤4例,术后均未放疗和化疗。2例患者分别术后11个月、27个月复发及转移,均为恶性肿瘤,术后生存时间分别为23个月和32个月,其余患者均未复发及转移。结论 SFTP是一种少见间叶组织的肿瘤,手术切除是一种有效的治疗方法,预后良好。
文摘A case of a successfully treated solitary fibrous tumor (SFT) of the liver is reported.An 82-year-old female presented with left upper abdominal discomfort,a firm mass on palpation,and imaging studies revealed a large tumor,15 cm in diameter,arising from the left lobe of the liver.A formal left hepatectomy was performed.Microscopic evaluation showed spindle and fibroblast-like cells within the collagenous stroma.Immunohistochemistry disclosed diffuse CD34 and positive vimentin,supporting the diagnosis of a benign SFT.The patient remained well 21 months after surgery.SFT of the liver is a very rare neoplasm of mesenchymal origin.In most cases it is a benign lesion,although some may have malignant histological features and recur locally or metastasize.With less than 30 reported cases in the literature,little can be said regarding its natural history or the benefits of adjuvant radiochemotherapy.Complete surgical resection remains the cornerstone of its treatment.
