《精神障碍诊断与统计手册》（Diagnostic and Statistical Manual of Mental Disorders,DSM）是由美国精神病学协会（APA）发表,在国际上应用最为广泛、影响较大的精神障碍诊断工具.随着人们对神经影像学、遗传学及行为科学等方面研究...《精神障碍诊断与统计手册》（Diagnostic and Statistical Manual of Mental Disorders,DSM）是由美国精神病学协会（APA）发表,在国际上应用最为广泛、影响较大的精神障碍诊断工具.随着人们对神经影像学、遗传学及行为科学等方面研究的不断深入,对精神疾病的认识也不断扩展,DSM自1952年出版以来就不断定期更新.展开更多
The pathogenesis of Functional Dyspepsia （FD） remains unclear, appears diverse and is thus inadequately understood. Akin to other functional gastrointestinal disorders, research has demonstrated an association betwe...The pathogenesis of Functional Dyspepsia （FD） remains unclear, appears diverse and is thus inadequately understood. Akin to other functional gastrointestinal disorders, research has demonstrated an association between this common diagnosis and psychosocial factors and psychiatric morbidity. Conceptualising the relevance of these factors within the syndrome of FD requires application of the biopsychosocial model of disease. Using this paradigm, dysregulation of the reciprocal communication between the brain and the gut is central to symptom generation, interpretation and exacerbation. Appreciation and understanding of the neurobiological correlates of various psychological states is also relevant. The view that psychosocial factors exert their influence in FD predominantly through motivation of health care seeking also persists. This appears too one-dimensional an assertion in light of the evidence available supporting a more intdnsic aetiological link. Evolving understanding of pathogenic mechanisms and the heterogeneous nature of the syndrome will facilitate effective management. Co-morbid psychiatric illness warrants treatment with conventional therapies. Acknowledging the relevance of psychosocial variables in FD, the degree of which is subject to vadation, has implications for assessment and management. Available evidence suggests psychological therapies may benefit FD patients particularly those with chronic symptoms. The rationale for use of psychotropic medications in FD is apparent but the evidence base to support the use of antidepressant pharmacotherapy is to date limited.展开更多
我国精神分裂症等精神病性障碍患者近1000万[1],患者病情迁延难愈、功能受损严重。国内外对于糖尿病、心脑血管病等慢性疾病的早期预防已经深入人心,但早期预防在精神疾病中的认识却还有不足。精神病性障碍患者常青壮年起病,给个人、家...我国精神分裂症等精神病性障碍患者近1000万[1],患者病情迁延难愈、功能受损严重。国内外对于糖尿病、心脑血管病等慢性疾病的早期预防已经深入人心,但早期预防在精神疾病中的认识却还有不足。精神病性障碍患者常青壮年起病,给个人、家庭及社会带来沉重负担,而且该病具有治疗有效率低、复发率高、并发症多等特点,进一步凸显对这一群体进行病前早期识别和发病风险防控的重要性。精神病性障碍风险人群有效识别和干预是全球前沿课题,在过去三十年里,国内外学者在各国政府和基金的支持下,投入大量人力物力在精神病首次发作前构建二级防控网,已卓有成效[2]。我国学者在科技部等基金项目支持下,对此也做出重要贡献。中国神经科学学会精神病学基础与临床分会(Chinese Society of Neuroscience Psychiatry,CSNP)精神病性障碍研究联盟组织该领域的23名专家(文末附参与专家姓名和单位),以近年国际研究成果为基础,专家组对文稿和建议进行了3轮讨论、8次修改和完善,至2020年4月1日完成所有信息和意见的收集,整理后撰写形成“中国精神病临床高危综合征早期识别和干预专家共识”,旨在协助临床工作者科学处理临床上存在精神病发病风险的人群,即精神病临床高危综合征(clinical high risk,CHR),为精准防治精神病性障碍做出积极贡献。展开更多
文摘《精神障碍诊断与统计手册》（Diagnostic and Statistical Manual of Mental Disorders,DSM）是由美国精神病学协会（APA）发表,在国际上应用最为广泛、影响较大的精神障碍诊断工具.随着人们对神经影像学、遗传学及行为科学等方面研究的不断深入,对精神疾病的认识也不断扩展,DSM自1952年出版以来就不断定期更新.
文摘The pathogenesis of Functional Dyspepsia （FD） remains unclear, appears diverse and is thus inadequately understood. Akin to other functional gastrointestinal disorders, research has demonstrated an association between this common diagnosis and psychosocial factors and psychiatric morbidity. Conceptualising the relevance of these factors within the syndrome of FD requires application of the biopsychosocial model of disease. Using this paradigm, dysregulation of the reciprocal communication between the brain and the gut is central to symptom generation, interpretation and exacerbation. Appreciation and understanding of the neurobiological correlates of various psychological states is also relevant. The view that psychosocial factors exert their influence in FD predominantly through motivation of health care seeking also persists. This appears too one-dimensional an assertion in light of the evidence available supporting a more intdnsic aetiological link. Evolving understanding of pathogenic mechanisms and the heterogeneous nature of the syndrome will facilitate effective management. Co-morbid psychiatric illness warrants treatment with conventional therapies. Acknowledging the relevance of psychosocial variables in FD, the degree of which is subject to vadation, has implications for assessment and management. Available evidence suggests psychological therapies may benefit FD patients particularly those with chronic symptoms. The rationale for use of psychotropic medications in FD is apparent but the evidence base to support the use of antidepressant pharmacotherapy is to date limited.
文摘我国精神分裂症等精神病性障碍患者近1000万[1],患者病情迁延难愈、功能受损严重。国内外对于糖尿病、心脑血管病等慢性疾病的早期预防已经深入人心,但早期预防在精神疾病中的认识却还有不足。精神病性障碍患者常青壮年起病,给个人、家庭及社会带来沉重负担,而且该病具有治疗有效率低、复发率高、并发症多等特点,进一步凸显对这一群体进行病前早期识别和发病风险防控的重要性。精神病性障碍风险人群有效识别和干预是全球前沿课题,在过去三十年里,国内外学者在各国政府和基金的支持下,投入大量人力物力在精神病首次发作前构建二级防控网,已卓有成效[2]。我国学者在科技部等基金项目支持下,对此也做出重要贡献。中国神经科学学会精神病学基础与临床分会(Chinese Society of Neuroscience Psychiatry,CSNP)精神病性障碍研究联盟组织该领域的23名专家(文末附参与专家姓名和单位),以近年国际研究成果为基础,专家组对文稿和建议进行了3轮讨论、8次修改和完善,至2020年4月1日完成所有信息和意见的收集,整理后撰写形成“中国精神病临床高危综合征早期识别和干预专家共识”,旨在协助临床工作者科学处理临床上存在精神病发病风险的人群,即精神病临床高危综合征(clinical high risk,CHR),为精准防治精神病性障碍做出积极贡献。
