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A Simplified Approach to Analysis of High-Rise Frame Tube Structures
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作者 周岱 周笠人 刘红玉 《Journal of Shanghai Jiaotong university(Science)》 EI 2003年第1期92-97,共6页
Based on finite element method and finite strip method, a simplified approach was presented to analyze high rise frame tube structures. The generalized strip element is introduced and then the generalized stiffness ma... Based on finite element method and finite strip method, a simplified approach was presented to analyze high rise frame tube structures. The generalized strip element is introduced and then the generalized stiffness matrices for beam and column line are derived by using the displacement functions that describe the nodal displacements and displacement transforms. Furthermore, the formulas for the generalized stiffness matrix of generalized strip element and load arrays corresponding to the displacement parameters were developed. It is shown through a series of numerical computation that the nodal angular displacements at the same floor in a generalized strip element are approximately identical. A comparison of the finite element method and the finite strip method shows that the simplified approach not only is accurate, but also reduces the number of basic unknown quantities. 展开更多
关键词 beam column line framed generalized strip element generalized stiffness matrix
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一种新的半数效量测定方法——简化随机逼近法
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作者 聂莉 潘伟 宋建国 《中国临床药理学与治疗学》 CAS CSCD 2010年第10期1139-1142,共4页
目的:本文根据序贯法原理设计了一种新的测定药物半数效量的方法:简化随机逼近法。并初步探讨了该法的可靠性和优缺点。方法:采用简化随机逼近法测定了普鲁卡因和戊四氮腹腔注射对小鼠的LD50,并与经典的Bliss法进行比较。结果:简化随机... 目的:本文根据序贯法原理设计了一种新的测定药物半数效量的方法:简化随机逼近法。并初步探讨了该法的可靠性和优缺点。方法:采用简化随机逼近法测定了普鲁卡因和戊四氮腹腔注射对小鼠的LD50,并与经典的Bliss法进行比较。结果:简化随机逼近法测得的普鲁卡因和戊四氮的LD50分别为207.5mg/kg、107.2mg/kg,而Bliss法测得的LD50分别为206.1mg/kg和101.2mg/kg。两法测定结果相近,但简化随机逼近法更为省时、省动物且计算简便。结论:简化随机逼近法适用于药效反应快、终点判定所需时间短的药物LD50或ED50的测定。 展开更多
关键词 简化随机逼近 Bliss法 LD50 普鲁卡因 戊四氮
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