Objective： To evaluate the pelvic lymph node coverage of conventional pelvic fields based on bony landmarks in Chinese patients with cervical cancer by using computed tomography （CT） simulation images to contour pe...Objective： To evaluate the pelvic lymph node coverage of conventional pelvic fields based on bony landmarks in Chinese patients with cervical cancer by using computed tomography （CT） simulation images to contour pelvic vessels as substitutes for lymph nodes location. Methods： A retrospective review of CT simulation images and conventional pelvic radiation planning data sets was performed in 100 patients with cervical cancer at the International Federation of Gynecology and Obstetrics （FIGO） Stage liB to IIIB in our hospital. Pelvic arteries were contoured on CT simulation images, and the outlines of conventional pelvic fields were drawn as defined by the gynecologic oncology group （GOG） after hiding the contours. The distances between the following vessel contours and field borders were measured： D1, the superior border of the anterior/posterior （AP） field and the bifurcation of abdominal aorta; D2, the ipsilateral border of the AP field and the distal end of external iliac artery; and D3, the anterior border of the lateral （LAT） field and the distal end of the external iliac artery. The distances were recorded as positive values if the measuring point was within the conventional pelvic fields, or they were recorded as negative values. Lymph nodes coverage was considered adequate when D1≥0 mm, D2〉17 mm or D3≥7 mm. Results： All patients had at least 1 inadequate margin, 97 patients （97.0%） had 2, and 22 patients （22.0%） had all the 3. On the AP field, 95 patients （95%） had the measuring point, the bifurcation of the abdominal aorta, out of the field （D1〈0 mm）, and all the patients had a distance less than 17.0 mm between the distal end of the external iliac artery and ipsilateral border （D2〈1 7.0 mm）. On the LAT field, 24 patients （24%） had a distance less than 7.0 mm between the distal end of the external iliac artery and anterior border （D3〈7.0 mm）. Conclusion： We observed that conventional pelvic fields based on bony landmarks provided inadeq展开更多
To evaluate detection rate, topography and false negatives of sentinel lymph node in endometrial cancer. Material and methods. Twenty-six patients were included. Lymphoscintigraphy was performed the day before surgery...To evaluate detection rate, topography and false negatives of sentinel lymph node in endometrial cancer. Material and methods. Twenty-six patients were included. Lymphoscintigraphy was performed the day before surgery. Preoperative detection of the sentinel lymph node was performed with cervical blue dye injection and a gamma probe. Separate pathology examinations were performed for sentinel and non-sentinel lymph nodes. Sentinel lymph nodes were examined with hematoxylin-eosin-safran stain, and immunohistochemistry if negative. Results. Twenty-six patients had a positive lymphoscintigraphy. Preoperative detection was successful in 21 patients (80.8% ): the detection rate with isotopic method, 19 cases (73.1% ), was superior to the dye detection, 15 cases (57.7% ). No isolated lombo-aortic sentinel lymph nodes were observed, and all sentinel lymph nodes were in the ilio-obturator region. Seven patients presented lymphatic spread, and 4 of them had at least one sentinel node. There was one micrometastasis in sentinel node, associated with isolated tumoral cells in pelvic lymphadenectomy. There was no false negative of sentinel node. Conclusion. The biopsy of sentinel lymph node is a feasible procedure in endometrial cancer. There was one micrometastatic sentinel node. However there was no isolated lombo-aortic sentinel lymph node in this study.展开更多
文摘Objective： To evaluate the pelvic lymph node coverage of conventional pelvic fields based on bony landmarks in Chinese patients with cervical cancer by using computed tomography （CT） simulation images to contour pelvic vessels as substitutes for lymph nodes location. Methods： A retrospective review of CT simulation images and conventional pelvic radiation planning data sets was performed in 100 patients with cervical cancer at the International Federation of Gynecology and Obstetrics （FIGO） Stage liB to IIIB in our hospital. Pelvic arteries were contoured on CT simulation images, and the outlines of conventional pelvic fields were drawn as defined by the gynecologic oncology group （GOG） after hiding the contours. The distances between the following vessel contours and field borders were measured： D1, the superior border of the anterior/posterior （AP） field and the bifurcation of abdominal aorta; D2, the ipsilateral border of the AP field and the distal end of external iliac artery; and D3, the anterior border of the lateral （LAT） field and the distal end of the external iliac artery. The distances were recorded as positive values if the measuring point was within the conventional pelvic fields, or they were recorded as negative values. Lymph nodes coverage was considered adequate when D1≥0 mm, D2〉17 mm or D3≥7 mm. Results： All patients had at least 1 inadequate margin, 97 patients （97.0%） had 2, and 22 patients （22.0%） had all the 3. On the AP field, 95 patients （95%） had the measuring point, the bifurcation of the abdominal aorta, out of the field （D1〈0 mm）, and all the patients had a distance less than 17.0 mm between the distal end of the external iliac artery and ipsilateral border （D2〈1 7.0 mm）. On the LAT field, 24 patients （24%） had a distance less than 7.0 mm between the distal end of the external iliac artery and anterior border （D3〈7.0 mm）. Conclusion： We observed that conventional pelvic fields based on bony landmarks provided inadeq
文摘To evaluate detection rate, topography and false negatives of sentinel lymph node in endometrial cancer. Material and methods. Twenty-six patients were included. Lymphoscintigraphy was performed the day before surgery. Preoperative detection of the sentinel lymph node was performed with cervical blue dye injection and a gamma probe. Separate pathology examinations were performed for sentinel and non-sentinel lymph nodes. Sentinel lymph nodes were examined with hematoxylin-eosin-safran stain, and immunohistochemistry if negative. Results. Twenty-six patients had a positive lymphoscintigraphy. Preoperative detection was successful in 21 patients (80.8% ): the detection rate with isotopic method, 19 cases (73.1% ), was superior to the dye detection, 15 cases (57.7% ). No isolated lombo-aortic sentinel lymph nodes were observed, and all sentinel lymph nodes were in the ilio-obturator region. Seven patients presented lymphatic spread, and 4 of them had at least one sentinel node. There was one micrometastasis in sentinel node, associated with isolated tumoral cells in pelvic lymphadenectomy. There was no false negative of sentinel node. Conclusion. The biopsy of sentinel lymph node is a feasible procedure in endometrial cancer. There was one micrometastatic sentinel node. However there was no isolated lombo-aortic sentinel lymph node in this study.
