目的:评估美国国立综合癌症网(National Comprehensive Cancer Network,NCCN)推荐的心理痛苦温度计(Distress Thermometer,DT)在中国癌症患者中的使用情况,探索癌症患者显著心理痛苦的检出率并探讨影响心理痛苦的危险因素。方法:使用DT...目的:评估美国国立综合癌症网(National Comprehensive Cancer Network,NCCN)推荐的心理痛苦温度计(Distress Thermometer,DT)在中国癌症患者中的使用情况,探索癌症患者显著心理痛苦的检出率并探讨影响心理痛苦的危险因素。方法:使用DT,对北京肿瘤医院2007年9月-2008年1月间新入院治疗的4815例癌症患者进行心理痛苦筛查。通过描述性统计分析中国癌症患者显著心理痛苦(DT≥4分)的检出率及其产生的主要因素;根据医院统计部门提供的入组本次研究对象的部分人口社会学资料,分析年龄、性别、癌症类型、职业等对显著心理痛苦检出率的影响,Logistics回归分析探讨心理痛苦的预测因素。结果:DT筛查结果显示,我国癌症患者显著心理痛苦的总体检出率为24.2%;引起心理痛苦的主要原因有:担忧、疲乏、睡眠、疼痛、经济问题、记忆力/注意力下降、紧张、进食困难、恶心及手脚麻木等。由问题列表中的情绪问题引起的心理痛苦比例占总样本量的13.5%;多因素分析显示女性是出现显著心理痛苦的危险因素(OR=1.459)。结论:心理痛苦温度计适用于对我国门诊及住院的癌症患者进行心理痛苦筛查,及时发现患者心理痛苦的程度和原因;对其进行测量学上信度和效度的检验后可以在全国范围内推广使用。展开更多
AIM:To evaluate the efficacy of simple and extended cholecystectomy for mucosa(T1a) or muscularis(T1b) gallbladder(GB) cancer. METHODS:Original studies on simple and extended cholecystectomy for T1a or T1b GB cancer w...AIM:To evaluate the efficacy of simple and extended cholecystectomy for mucosa(T1a) or muscularis(T1b) gallbladder(GB) cancer. METHODS:Original studies on simple and extended cholecystectomy for T1a or T1b GB cancer were searched from MEDLINE(PubMed) ,Cochrane Library,EMBase,and CancerLit using the search terms of GB,cancer/carcinoma/tumor/neoplasm. RESULTS:Twenty-nine out of the 2312 potentially relevant publications met the eligibility criteria.Of the 1266 patients with GB cancer included in the publications,706(55.8%) and 560(44.2%) had T1a and T1b GB cancer,respectively.Simple cholecystectomy for T1a and T1b GB cancer was performed in 590(83.6%) and 375(67.0%) patients,respectively(P<0.01) .In most series,the treatment of choice was simple cholecystectomy for T1a GB cancer patients with a 5-year survival rate of 100%.Lymph node metastasis was detected in 10.9% of the T1b GB cancer patients and in 1.8%of the T1a GB cancer patients,respectively(P<0.01) .Eight patients(1.1%) with T1a GB cancer and 52 patients(9.3%) with T1b GB cancer died of recurrent GB cancer(P<0.01) . CONCLUSION:Simple cholecystectomy represents the adequate treatment of T1a GB cancer.There is no definite evidence that extended cholecystectomy is advantageous over simple cholecystectomy for T1b GB cancer.展开更多
文摘目的:评估美国国立综合癌症网(National Comprehensive Cancer Network,NCCN)推荐的心理痛苦温度计(Distress Thermometer,DT)在中国癌症患者中的使用情况,探索癌症患者显著心理痛苦的检出率并探讨影响心理痛苦的危险因素。方法:使用DT,对北京肿瘤医院2007年9月-2008年1月间新入院治疗的4815例癌症患者进行心理痛苦筛查。通过描述性统计分析中国癌症患者显著心理痛苦(DT≥4分)的检出率及其产生的主要因素;根据医院统计部门提供的入组本次研究对象的部分人口社会学资料,分析年龄、性别、癌症类型、职业等对显著心理痛苦检出率的影响,Logistics回归分析探讨心理痛苦的预测因素。结果:DT筛查结果显示,我国癌症患者显著心理痛苦的总体检出率为24.2%;引起心理痛苦的主要原因有:担忧、疲乏、睡眠、疼痛、经济问题、记忆力/注意力下降、紧张、进食困难、恶心及手脚麻木等。由问题列表中的情绪问题引起的心理痛苦比例占总样本量的13.5%;多因素分析显示女性是出现显著心理痛苦的危险因素(OR=1.459)。结论:心理痛苦温度计适用于对我国门诊及住院的癌症患者进行心理痛苦筛查,及时发现患者心理痛苦的程度和原因;对其进行测量学上信度和效度的检验后可以在全国范围内推广使用。
文摘AIM:To evaluate the efficacy of simple and extended cholecystectomy for mucosa(T1a) or muscularis(T1b) gallbladder(GB) cancer. METHODS:Original studies on simple and extended cholecystectomy for T1a or T1b GB cancer were searched from MEDLINE(PubMed) ,Cochrane Library,EMBase,and CancerLit using the search terms of GB,cancer/carcinoma/tumor/neoplasm. RESULTS:Twenty-nine out of the 2312 potentially relevant publications met the eligibility criteria.Of the 1266 patients with GB cancer included in the publications,706(55.8%) and 560(44.2%) had T1a and T1b GB cancer,respectively.Simple cholecystectomy for T1a and T1b GB cancer was performed in 590(83.6%) and 375(67.0%) patients,respectively(P<0.01) .In most series,the treatment of choice was simple cholecystectomy for T1a GB cancer patients with a 5-year survival rate of 100%.Lymph node metastasis was detected in 10.9% of the T1b GB cancer patients and in 1.8%of the T1a GB cancer patients,respectively(P<0.01) .Eight patients(1.1%) with T1a GB cancer and 52 patients(9.3%) with T1b GB cancer died of recurrent GB cancer(P<0.01) . CONCLUSION:Simple cholecystectomy represents the adequate treatment of T1a GB cancer.There is no definite evidence that extended cholecystectomy is advantageous over simple cholecystectomy for T1b GB cancer.
