In this study,in vitro degradation and biocompatibility of Mg-Nd-Zn-Zr(NZK) alloy were investigated to determine its suitability as a degradable medical biomaterial.Its corrosion properties were evaluated by static im...In this study,in vitro degradation and biocompatibility of Mg-Nd-Zn-Zr(NZK) alloy were investigated to determine its suitability as a degradable medical biomaterial.Its corrosion properties were evaluated by static immersion test,electrochemical corrosion test,scanning electron microscopy(SEM),and energy dispersive spectroscopic(EDS) analysis,and in vitro biocompatibilities were assessed by hemolysis and cytotoxicity tests.Pure magnesium was used as control.The results of static immersion test and electrochemical corrosion test in simulated body fluid(SBF) demonstrated that the addition of alloying elements could improve the corrosion resistance.The hemolysis test found that the hemolysis rate of calcium phosphate coated NZK alloy was 4.8%,which was lower than the safe value of 5%.The cytotoxicity test indicated that NZK alloy extracts did not significantly reduce MC3T3-E1 cell viability.Hemolysis test and cytotoxicity test display excellent hemocompatibility and cytocompatibility of NZK alloy in vitro.Our data indicate that NZK alloy has excellent biocompatibility and thus can be considered as a potential degradable medical biomaterial for orthopedic applications.展开更多
The application of semisolid process was investigated on Pb-Sb alloys that are normally used for metallic parts in car batteries, in order to increase their mechanical properties and corrosion resistance.The semisolid...The application of semisolid process was investigated on Pb-Sb alloys that are normally used for metallic parts in car batteries, in order to increase their mechanical properties and corrosion resistance.The semisolid behaviour of a Pb-4%Sb alloy was analysed by means of rheological and calorimetry differential scanning experiments.The alloy was melted, treated by ultrasound to obtain the semisolid state and then poured into permanent moulds.Some of these samples were also heated in semisolid temperature range and injected in thixo-casting apparatus.Both poured and injected samples were characterized by metallographic analysis, mechanical test and electrochemical corrosion experiments.The results show an improvement of mechanical and corrosion resistance with respect to samples obtained by conventional casting technique.展开更多
基金supported by the National Natural Science Foundation of China (81071452 and 30772182)
文摘In this study,in vitro degradation and biocompatibility of Mg-Nd-Zn-Zr(NZK) alloy were investigated to determine its suitability as a degradable medical biomaterial.Its corrosion properties were evaluated by static immersion test,electrochemical corrosion test,scanning electron microscopy(SEM),and energy dispersive spectroscopic(EDS) analysis,and in vitro biocompatibilities were assessed by hemolysis and cytotoxicity tests.Pure magnesium was used as control.The results of static immersion test and electrochemical corrosion test in simulated body fluid(SBF) demonstrated that the addition of alloying elements could improve the corrosion resistance.The hemolysis test found that the hemolysis rate of calcium phosphate coated NZK alloy was 4.8%,which was lower than the safe value of 5%.The cytotoxicity test indicated that NZK alloy extracts did not significantly reduce MC3T3-E1 cell viability.Hemolysis test and cytotoxicity test display excellent hemocompatibility and cytocompatibility of NZK alloy in vitro.Our data indicate that NZK alloy has excellent biocompatibility and thus can be considered as a potential degradable medical biomaterial for orthopedic applications.
文摘The application of semisolid process was investigated on Pb-Sb alloys that are normally used for metallic parts in car batteries, in order to increase their mechanical properties and corrosion resistance.The semisolid behaviour of a Pb-4%Sb alloy was analysed by means of rheological and calorimetry differential scanning experiments.The alloy was melted, treated by ultrasound to obtain the semisolid state and then poured into permanent moulds.Some of these samples were also heated in semisolid temperature range and injected in thixo-casting apparatus.Both poured and injected samples were characterized by metallographic analysis, mechanical test and electrochemical corrosion experiments.The results show an improvement of mechanical and corrosion resistance with respect to samples obtained by conventional casting technique.
