Six sesquiterpenes, including three guaiane type sesquiterpenes （1-3）, one oplopanone type sesquiterpene （4）, one xanthane type sesquiterpene （5） and one salvialane type sesquiterpene （6）, were isolated from A...Six sesquiterpenes, including three guaiane type sesquiterpenes （1-3）, one oplopanone type sesquiterpene （4）, one xanthane type sesquiterpene （5） and one salvialane type sesquiterpene （6）, were isolated from Alisma plantago-aquatica for the first time. The structures of these six compounds were elucidated as alismoxide （1）, alismol （2）, orientalol B （3）, oplopanone （4）, gibberodione （5）, and 7a, lOa-epoxy-salvialan-1Ofl-ol （6）, respectively, among which 6 was a new natural product. Xanthane type and salvialane type sesquiterpenes were obtained from the genus Alisma for the first time. In addition, a plausible biosynthetic pathway for all isolates was discussed.展开更多
基金supported by the National Natural Science Foundation of China(No.21172024 to L.-M.Li)the Key Project of Chinese Ministry of Education(No.212151)+3 种基金the NSFC-Joint Foundation of Yunnan Province(No.U0832602 to H.-D. Sun)the Major State Basic Research Development Program of China(Nos. 2009CB522300 and 2009CB940900)the Science and Technology Program of Yunnan Province(Nos. 2008IF010 and 2008CD162)the Major Direction Projection Foundation of CAS Intellectual Innovation Project(No.2010KIBA05 to J.-X.Pu)~~
基金The National Science and Technology Major Project of“Technological study on the safety and standards of Chinese materia medica”(Grant No.2014ZX09304307-001-011)Chinese materia medica supporting program of“Quality control base construction of Chinese material medica including Isatidis Radix,Carthami Flos,etc”by Ministry of Industry and Information Technology of Peoples Republic of China
文摘Six sesquiterpenes, including three guaiane type sesquiterpenes （1-3）, one oplopanone type sesquiterpene （4）, one xanthane type sesquiterpene （5） and one salvialane type sesquiterpene （6）, were isolated from Alisma plantago-aquatica for the first time. The structures of these six compounds were elucidated as alismoxide （1）, alismol （2）, orientalol B （3）, oplopanone （4）, gibberodione （5）, and 7a, lOa-epoxy-salvialan-1Ofl-ol （6）, respectively, among which 6 was a new natural product. Xanthane type and salvialane type sesquiterpenes were obtained from the genus Alisma for the first time. In addition, a plausible biosynthetic pathway for all isolates was discussed.
