Purpose. To ascertain the therapeutic effect of periocular corticosteroids in diabetic papillopathy. Methods. Prospec-tively, five consecutive adult-onset diabetic patients with symptomatic diabetic papillopathy under...Purpose. To ascertain the therapeutic effect of periocular corticosteroids in diabetic papillopathy. Methods. Prospec-tively, five consecutive adult-onset diabetic patients with symptomatic diabetic papillopathy underwent visual fields and fluorescein angiography before and after superonasal subtenon injection of corticosteroids. Results. The median duration of papillopathy was 2.5 weeks by ophthalmoscopy and 3 weeks by fluorescein angiography. The median recovery time of best-spectacle-corrected visual acuity was 2 weeks. Two patients developed sequential diabetic papillopathy, and both reported faster visual recovery and better subjective vision in treated eyes. In these two patients, the final best-spectacle-corrected visual acuity and visual evoked responses were comparable between the two eyes, while automated visual fields were less constricted in treated eyes. Complications included ocular hypertension, mild progression of cataract, and mild ptosis in one patient each. Conclusions. Periocular corticosteroids shortened the duration of diabetic papillopathy from a reported median of 5 months to 3 weeks in the present uncontrolled observational study, partly by their angiostatic and antioedema effects at the level of the anterior optic nerve. Intraocular pressure needs to be monitored in eyes receiving periocular corticosteroids.展开更多
目的探讨高眼压下球筋膜囊下麻醉联合表面麻醉复合式小梁切除术并发症的预防及处理。方法对28例(35只眼)高眼压急性闭角型青光眼(眼压>40 mm Hg,1 mm Hg=0.133 k Pa)球筋膜囊下麻醉联合表面麻醉下行复合式小梁切除术,术后严密观察前...目的探讨高眼压下球筋膜囊下麻醉联合表面麻醉复合式小梁切除术并发症的预防及处理。方法对28例(35只眼)高眼压急性闭角型青光眼(眼压>40 mm Hg,1 mm Hg=0.133 k Pa)球筋膜囊下麻醉联合表面麻醉下行复合式小梁切除术,术后严密观察前房、眼压、视力、滤过泡等。结果 31只眼(88.6%)眼压<21 mm Hg,3只眼术后应用1~2种降眼压药物眼压<21 mm Hg维持观察、应用2种降眼压药物眼压>21 mm Hg,2个月后再次复合式小梁切除术后眼压控制,术后浅前房低眼压3只眼,2周前房加深,眼压正常;术后第1天35眼均形成前房,无Ⅲ级浅前房;6~12个月随诊31眼形成功能性滤过泡;所有患者视力均较术前有所提高,26眼(74.3%)视力提高2行以上;出院视力在0.1以上28只眼;术中术后未见严重并发症。结论通过术中规范仔细操作,术中缓慢放液高眼压下球筋膜囊下麻醉联合表面麻醉复合式小梁切除术治疗急性闭角型青光眼是安全有效的。展开更多
文摘Purpose. To ascertain the therapeutic effect of periocular corticosteroids in diabetic papillopathy. Methods. Prospec-tively, five consecutive adult-onset diabetic patients with symptomatic diabetic papillopathy underwent visual fields and fluorescein angiography before and after superonasal subtenon injection of corticosteroids. Results. The median duration of papillopathy was 2.5 weeks by ophthalmoscopy and 3 weeks by fluorescein angiography. The median recovery time of best-spectacle-corrected visual acuity was 2 weeks. Two patients developed sequential diabetic papillopathy, and both reported faster visual recovery and better subjective vision in treated eyes. In these two patients, the final best-spectacle-corrected visual acuity and visual evoked responses were comparable between the two eyes, while automated visual fields were less constricted in treated eyes. Complications included ocular hypertension, mild progression of cataract, and mild ptosis in one patient each. Conclusions. Periocular corticosteroids shortened the duration of diabetic papillopathy from a reported median of 5 months to 3 weeks in the present uncontrolled observational study, partly by their angiostatic and antioedema effects at the level of the anterior optic nerve. Intraocular pressure needs to be monitored in eyes receiving periocular corticosteroids.
文摘目的探讨高眼压下球筋膜囊下麻醉联合表面麻醉复合式小梁切除术并发症的预防及处理。方法对28例(35只眼)高眼压急性闭角型青光眼(眼压>40 mm Hg,1 mm Hg=0.133 k Pa)球筋膜囊下麻醉联合表面麻醉下行复合式小梁切除术,术后严密观察前房、眼压、视力、滤过泡等。结果 31只眼(88.6%)眼压<21 mm Hg,3只眼术后应用1~2种降眼压药物眼压<21 mm Hg维持观察、应用2种降眼压药物眼压>21 mm Hg,2个月后再次复合式小梁切除术后眼压控制,术后浅前房低眼压3只眼,2周前房加深,眼压正常;术后第1天35眼均形成前房,无Ⅲ级浅前房;6~12个月随诊31眼形成功能性滤过泡;所有患者视力均较术前有所提高,26眼(74.3%)视力提高2行以上;出院视力在0.1以上28只眼;术中术后未见严重并发症。结论通过术中规范仔细操作,术中缓慢放液高眼压下球筋膜囊下麻醉联合表面麻醉复合式小梁切除术治疗急性闭角型青光眼是安全有效的。
