一、UC生存质量量表 目前多采用普适性和疾病特异性量表评估UC患者的生存质量.常用的普适性量表有健康调查简表（short form 36 health survey questionnaire,SF-36）、疾病影响程度量表、世界卫生组织生存质量量表、短期健康量表等[1]....一、UC生存质量量表 目前多采用普适性和疾病特异性量表评估UC患者的生存质量.常用的普适性量表有健康调查简表（short form 36 health survey questionnaire,SF-36）、疾病影响程度量表、世界卫生组织生存质量量表、短期健康量表等[1].SF-36简单明了,临床常用,是国际上普遍认可的具有较好信度和效度的普适性生存质量量表[2].目前国内的中文版SF-36效度和信度均尚可,其在IBD应用中的可接受度和合格率均达到要求[3].虽然SF-36未包括一些特异条目,不能全面反映患者的生存质量,但在辨别组间疾病特异性变化、疾病活动程度方面具优势.中医脾胃系疾病生存质量量表包含形、神、情志三大领域,各领域间相关性良好,敏感度高于SF-36[4].疾病特异性量表适合对某一特定疾病进行评估.UC和CD是IBD的不同亚型,组织损伤和基本病理过程相似,由于目前尚少有专门针对UC的生存质量量表,故UC患者生存质量的研究多采用IBD相关量表,主要有IBD问卷（inflammatory bowel disease questionnaire,IBDQ）、IBD患者关注评分表[5-6]等,其中以IBDQ最为常用.中文版IBDQ具有良好的信度和效度,适用于评价中国患者的生存质量[7].展开更多
Heterogeneity in respiratory syncytial virus (RSV) disease severity likely is due to a combination of host and viral factors.Infection with RSV subgroup A is thought to produce more severe disease than RSV-B.Higher RS...Heterogeneity in respiratory syncytial virus (RSV) disease severity likely is due to a combination of host and viral factors.Infection with RSV subgroup A is thought to produce more severe disease than RSV-B.Higher RSV loads correlate with greater disease severity in hospitalized infants.Whether subgroup-specific variations in disease severity result from differences in RSV load has not been studied.A total of 102 RSV-hospitalized infants < 2 y of age were studied.Nasal washes were collected in a standardized manner and were cultured in < 3 h in parallel with an RSV quantitative standard in a HEp-2 plaque assay.RSV-A (72%) was more frequent than RSV-B.Disease severity risk factors were similar between subgroups.RSV load swere similar between A and B subgroups (4.77 versus 4.68 log PFU/mL).Measures of disease severity were also similar between subgroups.展开更多
文摘一、UC生存质量量表 目前多采用普适性和疾病特异性量表评估UC患者的生存质量.常用的普适性量表有健康调查简表（short form 36 health survey questionnaire,SF-36）、疾病影响程度量表、世界卫生组织生存质量量表、短期健康量表等[1].SF-36简单明了,临床常用,是国际上普遍认可的具有较好信度和效度的普适性生存质量量表[2].目前国内的中文版SF-36效度和信度均尚可,其在IBD应用中的可接受度和合格率均达到要求[3].虽然SF-36未包括一些特异条目,不能全面反映患者的生存质量,但在辨别组间疾病特异性变化、疾病活动程度方面具优势.中医脾胃系疾病生存质量量表包含形、神、情志三大领域,各领域间相关性良好,敏感度高于SF-36[4].疾病特异性量表适合对某一特定疾病进行评估.UC和CD是IBD的不同亚型,组织损伤和基本病理过程相似,由于目前尚少有专门针对UC的生存质量量表,故UC患者生存质量的研究多采用IBD相关量表,主要有IBD问卷（inflammatory bowel disease questionnaire,IBDQ）、IBD患者关注评分表[5-6]等,其中以IBDQ最为常用.中文版IBDQ具有良好的信度和效度,适用于评价中国患者的生存质量[7].
文摘Heterogeneity in respiratory syncytial virus (RSV) disease severity likely is due to a combination of host and viral factors.Infection with RSV subgroup A is thought to produce more severe disease than RSV-B.Higher RSV loads correlate with greater disease severity in hospitalized infants.Whether subgroup-specific variations in disease severity result from differences in RSV load has not been studied.A total of 102 RSV-hospitalized infants < 2 y of age were studied.Nasal washes were collected in a standardized manner and were cultured in < 3 h in parallel with an RSV quantitative standard in a HEp-2 plaque assay.RSV-A (72%) was more frequent than RSV-B.Disease severity risk factors were similar between subgroups.RSV load swere similar between A and B subgroups (4.77 versus 4.68 log PFU/mL).Measures of disease severity were also similar between subgroups.
