PURPOSE: To examine the influence of optic material (silicone and hydrophobic acrylic) and haptic design (one-piece and three-piece open loop) of sharp optic edge intraocular lenses (IOL) on anterior capsule opacifica...PURPOSE: To examine the influence of optic material (silicone and hydrophobic acrylic) and haptic design (one-piece and three-piece open loop) of sharp optic edge intraocular lenses (IOL) on anterior capsule opacification (ACO) and capsulorrhexis contraction. DESIGN: Randomized,controlled,double-blind clinical trial with intraindividual comparison. METHODS: This study was performed at the Department of Ophthalmology,Medical University of Vienna,Austria,and comprised 210 eyes of 105 patients with bilateral age-related cataract. In group 1 (n=53 patients),a three-piece acrylic IOL was compared with a three-piece silicone IOL. In group 2 (n=52 patients),the three-piece acrylic IOL was compared with the one-piece acrylic IOL. One year after the operation,standardized digital slit-lamp images of ACO were taken; 1 week and 1 year after the operation,digital retroillumination images were taken to assess capsulorrhexis size. The intensity of ACO was graded objectively (score,0% to 100% ),and the capsulorrhexis area (square millimeters) was determined objectively. RESULTS: One year after surgery,the mean ACO score was 21% for the acrylic and 20% for the silicone IOL (P =.4) in group 1 and 18% for both the three-piece and one-piece acrylic IOLs (P=.87) in group 2. Concerning the amount of capsulorrhexis contraction,there was no significant difference between the IOL types that were evaluated in this study (after Bonferroni-Holm correction,P > .05). CONCLUSION: In the hydrophobic sharp optic edge IOLs that were examined,neither the optic material nor the haptic design had an influence on the amount of ACO or capsulorrhexis contraction.展开更多
文摘PURPOSE: To examine the influence of optic material (silicone and hydrophobic acrylic) and haptic design (one-piece and three-piece open loop) of sharp optic edge intraocular lenses (IOL) on anterior capsule opacification (ACO) and capsulorrhexis contraction. DESIGN: Randomized,controlled,double-blind clinical trial with intraindividual comparison. METHODS: This study was performed at the Department of Ophthalmology,Medical University of Vienna,Austria,and comprised 210 eyes of 105 patients with bilateral age-related cataract. In group 1 (n=53 patients),a three-piece acrylic IOL was compared with a three-piece silicone IOL. In group 2 (n=52 patients),the three-piece acrylic IOL was compared with the one-piece acrylic IOL. One year after the operation,standardized digital slit-lamp images of ACO were taken; 1 week and 1 year after the operation,digital retroillumination images were taken to assess capsulorrhexis size. The intensity of ACO was graded objectively (score,0% to 100% ),and the capsulorrhexis area (square millimeters) was determined objectively. RESULTS: One year after surgery,the mean ACO score was 21% for the acrylic and 20% for the silicone IOL (P =.4) in group 1 and 18% for both the three-piece and one-piece acrylic IOLs (P=.87) in group 2. Concerning the amount of capsulorrhexis contraction,there was no significant difference between the IOL types that were evaluated in this study (after Bonferroni-Holm correction,P > .05). CONCLUSION: In the hydrophobic sharp optic edge IOLs that were examined,neither the optic material nor the haptic design had an influence on the amount of ACO or capsulorrhexis contraction.
