The bactericidal activities of two series of quaternary Gemini surfactants have been examined by the suspension quantitative germicidal tests against Escherchia, Staphylococcus aureus and Candida alibicans respectivel...The bactericidal activities of two series of quaternary Gemini surfactants have been examined by the suspension quantitative germicidal tests against Escherchia, Staphylococcus aureus and Candida alibicans respectively, the dodecyltrimethylammonium bromide(C 12TABr) was used for comparison. All of the quaternary Gemini surfactants showed superior bactericidal activities to C 12TABr due to higher densities in both headgroup charge and alkyl chains.展开更多
AIM： To investigate the bactericidal and anti-adhesive properties of 25 plants against Helicobacter pylori （H pylon）. METHODS： Twenty-five plants were boiled in water to produce aqueous extracts that simulate the ...AIM： To investigate the bactericidal and anti-adhesive properties of 25 plants against Helicobacter pylori （H pylon）. METHODS： Twenty-five plants were boiled in water to produce aqueous extracts that simulate the effect of cooking. The bactericidal activity of the extracts was assessed by a standard kill-curve with seven strains of H pylori. The anti-adhesive property was assessed by the inhibition of binding of four strains of FITC-labeled Hpylori to stomach sections. RESULTS： Of all the plants tested, eight plants, including Bengal quince, nightshade, garlic, dill, black pepper, coriander, fenugreek and black tea, were found to have no bactericidal effect on any of the isolates. Columbo weed, long pepper, parsley, tarragon, nutmeg, yellow-berried nightshade, threadstem carpetweed, sage and cinnamon had bactericidal activities against Hpylori, but total inhibition of growth was not achieved in this study. Among the plants that killed H pylori, turmeric was the most efficient, followed by cumin, ginger, chilli, borage, black caraway, oregano and liquorice. Moreover, extracts of turmeric, borage and parsley were able to inhibit the adhesion of H pylori strains to the stomach sections. CONCLUSION： Several plants that were tested in our study had bactericidal and/or anti-adhesive effects on Hpylori. Ingestion of the plants with anti-adhesive properties could therefore provide a potent alternative therapy for H pylori infection, which overcomes the problem of resistance associated with current antibiotic treatment.展开更多
为了解三氯羟基二苯醚含醇消毒凝胶杀菌作用及理化性能,采用载体定量杀菌试验和理化分析方法进行了实验室和现场实验观察。结果,以含质量分数1.55%的三氯羟基二苯醚和39.6%乙醇组成的消毒凝胶、pH值6.67条件下,对布片上的金黄色葡萄球...为了解三氯羟基二苯醚含醇消毒凝胶杀菌作用及理化性能,采用载体定量杀菌试验和理化分析方法进行了实验室和现场实验观察。结果,以含质量分数1.55%的三氯羟基二苯醚和39.6%乙醇组成的消毒凝胶、pH值6.67条件下,对布片上的金黄色葡萄球、铜绿假单胞杆菌、大肠杆菌和白色念珠菌作用0.5 m in,杀灭对数值均>5.00。用标准硬水将该消毒凝胶作对倍稀释,对金黄色葡萄球和白色念珠菌,作用1.0 m in,杀灭对数值分别为3.40和2.75。用该消毒凝胶原液对志愿者手及前臂皮肤进行擦拭消毒1.0 m in,对手部皮肤自然菌的杀灭对数值均>1.00。将该消毒凝胶原包装产品置于37℃恒温储存3个月,有效成分三氯羟基二苯醚和乙醇含量下降率分别为1.94%和1.01%。结论,三氯羟基二苯醚醇消毒凝胶对细菌繁殖体和真菌具有快速杀灭作用,对志愿者手皮肤上自然菌杀灭效果达到消毒合格要求,储存性能稳定。展开更多
文摘The bactericidal activities of two series of quaternary Gemini surfactants have been examined by the suspension quantitative germicidal tests against Escherchia, Staphylococcus aureus and Candida alibicans respectively, the dodecyltrimethylammonium bromide(C 12TABr) was used for comparison. All of the quaternary Gemini surfactants showed superior bactericidal activities to C 12TABr due to higher densities in both headgroup charge and alkyl chains.
基金Supported by the European Union on EC contract QLK2-CT-2001-01216(ADRI)
文摘AIM： To investigate the bactericidal and anti-adhesive properties of 25 plants against Helicobacter pylori （H pylon）. METHODS： Twenty-five plants were boiled in water to produce aqueous extracts that simulate the effect of cooking. The bactericidal activity of the extracts was assessed by a standard kill-curve with seven strains of H pylori. The anti-adhesive property was assessed by the inhibition of binding of four strains of FITC-labeled Hpylori to stomach sections. RESULTS： Of all the plants tested, eight plants, including Bengal quince, nightshade, garlic, dill, black pepper, coriander, fenugreek and black tea, were found to have no bactericidal effect on any of the isolates. Columbo weed, long pepper, parsley, tarragon, nutmeg, yellow-berried nightshade, threadstem carpetweed, sage and cinnamon had bactericidal activities against Hpylori, but total inhibition of growth was not achieved in this study. Among the plants that killed H pylori, turmeric was the most efficient, followed by cumin, ginger, chilli, borage, black caraway, oregano and liquorice. Moreover, extracts of turmeric, borage and parsley were able to inhibit the adhesion of H pylori strains to the stomach sections. CONCLUSION： Several plants that were tested in our study had bactericidal and/or anti-adhesive effects on Hpylori. Ingestion of the plants with anti-adhesive properties could therefore provide a potent alternative therapy for H pylori infection, which overcomes the problem of resistance associated with current antibiotic treatment.
文摘为了解三氯羟基二苯醚含醇消毒凝胶杀菌作用及理化性能,采用载体定量杀菌试验和理化分析方法进行了实验室和现场实验观察。结果,以含质量分数1.55%的三氯羟基二苯醚和39.6%乙醇组成的消毒凝胶、pH值6.67条件下,对布片上的金黄色葡萄球、铜绿假单胞杆菌、大肠杆菌和白色念珠菌作用0.5 m in,杀灭对数值均>5.00。用标准硬水将该消毒凝胶作对倍稀释,对金黄色葡萄球和白色念珠菌,作用1.0 m in,杀灭对数值分别为3.40和2.75。用该消毒凝胶原液对志愿者手及前臂皮肤进行擦拭消毒1.0 m in,对手部皮肤自然菌的杀灭对数值均>1.00。将该消毒凝胶原包装产品置于37℃恒温储存3个月,有效成分三氯羟基二苯醚和乙醇含量下降率分别为1.94%和1.01%。结论,三氯羟基二苯醚醇消毒凝胶对细菌繁殖体和真菌具有快速杀灭作用,对志愿者手皮肤上自然菌杀灭效果达到消毒合格要求,储存性能稳定。
