Introduction With the remarkable properties in mechanical,electronic and magnetic,fabrication of carbon nanotube (CNT) arrays has drawn ever-increasing worldwide attention in application of field emission display (FED...Introduction With the remarkable properties in mechanical,electronic and magnetic,fabrication of carbon nanotube (CNT) arrays has drawn ever-increasing worldwide attention in application of field emission display (FED) and展开更多
Polyurethane based on polypropylene glycol(PPG) and TDI using 3,3\|dichloride\|4,4\|methylenedianiline(MOCA) as the crosslinker is presented for the first time to fabricate molecular stamps(PU stamps) for the synt...Polyurethane based on polypropylene glycol(PPG) and TDI using 3,3\|dichloride\|4,4\|methylenedianiline(MOCA) as the crosslinker is presented for the first time to fabricate molecular stamps(PU stamps) for the synthesis of DNA microarray with contact procedure. The predictability of the process is achieved by utilizing commercially available starting materials. SEM analysis of the morphology of PU stamps and photoresist motherboard showed that PU elastomer could replicate subtly the motherboards patterns with a high fidelity. It was proved from the contact angle measurement that PU stamps surface has a good affinity with acetonitrile, which guarantee the well\|distribution of DNA monomers on patterned stamps. Laser confocal fluorescence microscopy images of oligonucleotide arrays confirm that polyurethane is an excellent material for molecular stamps.展开更多
基金This work was supported by 973 Basics Science Research Program （grant No. 2003CBT16203）the National Science Foundation of China （grant No. 50505037）+2 种基金 863 Hi-Tech Program （grant No. 2006AA04Z322 and No. 2006AA05Z411）Xi'An AM Foundation （grant No. XA-AM-200505 and No. XA-AM-200609 ）ShanXi Province Foundation （grant No. 2006E109).
文摘Introduction With the remarkable properties in mechanical,electronic and magnetic,fabrication of carbon nanotube (CNT) arrays has drawn ever-increasing worldwide attention in application of field emission display (FED) and
文摘Polyurethane based on polypropylene glycol(PPG) and TDI using 3,3\|dichloride\|4,4\|methylenedianiline(MOCA) as the crosslinker is presented for the first time to fabricate molecular stamps(PU stamps) for the synthesis of DNA microarray with contact procedure. The predictability of the process is achieved by utilizing commercially available starting materials. SEM analysis of the morphology of PU stamps and photoresist motherboard showed that PU elastomer could replicate subtly the motherboards patterns with a high fidelity. It was proved from the contact angle measurement that PU stamps surface has a good affinity with acetonitrile, which guarantee the well\|distribution of DNA monomers on patterned stamps. Laser confocal fluorescence microscopy images of oligonucleotide arrays confirm that polyurethane is an excellent material for molecular stamps.
