PURPOSE: To report three cases of nonarteritic anterior ischemic optic neuropa thy (NAION) that occurred in patients with sleep apnea syndrome (SAS) while bein g treated with continuous positive airway pressure (CPAP)...PURPOSE: To report three cases of nonarteritic anterior ischemic optic neuropa thy (NAION) that occurred in patients with sleep apnea syndrome (SAS) while bein g treated with continuous positive airway pressure (CPAP). DESI- GN: A prospective, noncomparative case series. METHODS: Prospective review of 108 patients with NAION diagnosed between 2002 and 2003 to identify any patients who developed NAION while being treated for SAS with CPAP. RESULTS: One patient had bilateral sequential NAION and two patients had unilateral NAION despite tr eatment with CPAP for SAS. All the patients were being treated with CPAP for a p eriod ranging from 4 months to 6 years before the onset of NAION. CONCLUSIONS: I n this series, CPAP did not prevent the development of NAION in SAS patients. Larger observational studies are needed to study the benefit of CPAP in preven ting NAION in patients with SAS.展开更多
Purpose. To evaluate the effect of intravitreal triamcinolone acetonide on visual acuity in branch retinal vein occlusion. Methods. The prospective comparative nonrandomized clinical interventional study included 28 p...Purpose. To evaluate the effect of intravitreal triamcinolone acetonide on visual acuity in branch retinal vein occlusion. Methods. The prospective comparative nonrandomized clinical interventional study included 28 patients (28 eyes) with branch retinal vein occlusion. The study group consisting of 10 consecutive patients received an intravitreal injection of 20- 25mg of triamcinolone acetonide. The control group including 18 patients did not receive an intravitreal injection. The mean follow-up was 8.7± 4.4 months. Results. In the study group, mean visual acuity increased significantly (P=0.02) from 0.27± 0.11 preoperatively to a best postoperative visual acuity of 0.45± 0.27. Visual acuity measurements determined 1 month after the injection were significantly (P=0.027) higher than baseline values. Nine (90% ) eyes gained in visual acuity, with six (60% ) eyes showing an increase in visual acuity of at least two Snellen lines. In the ischaemic subgroup, visual acuity did not change significantly (0.18± 0.18 to 0.13± 0.04; P=0.66), while, in the nonischaemic subgroup, visual acuity increased significantly (P=0.012) from the baseline value to the best postoperative measurement (0.29± 0.09 to 0.53± 0.24). In the control group, baseline visual acuity and best visual acuity during the follow-up did not vary significantly (P=0.27). Comparing the study and control groups with each other, the gain in visual acuity was significantly higher in the study group at 1 month (P=0.016) and 2 months (P=0.012) after baseline. Conclusions. Intravitreal injection of triamcinolone acetonide can increase visual acuity in patients with branch retinal vein occlusion.展开更多
Objective:To evaluate the effect of radial optic neurotomy on visual acuity(VA)and foveal thickness in patients with hemicentral retinal vein occlusion.Methods:A prospective noncomparative case series of 13 eyes in 13...Objective:To evaluate the effect of radial optic neurotomy on visual acuity(VA)and foveal thickness in patients with hemicentral retinal vein occlusion.Methods:A prospective noncomparative case series of 13 eyes in 13 patients with hemicentral retinal vein occlusion and a preoperative VA of 20/60 or less from a total of 232 retinal vein occlusions diagnosed.All patients underwent pars plana vitrectomy,posterior hyaloid dissection,and radial optic neurotomy at the nasal border of the optic disc.Results:Visual acuity and macular thickness were measured with optical coherence tomography.Nine patients(69.2%)gained 2 ormore Snellen lines of vision,and in 4 patients(30.8%)VA improved by 4 ormore Snellen lines(median visual acuity,20/50;mean VA,20/45;P<.01)(average gain,2.7 Snellen lines).The decrease in foveal thickness was statistically significant(P<.01)(median decrease,297 μ m).Final VA was statistically related to decreased macular thickness at optical coherence tomography(P=.03;ρ =-0.62).Retinochoroidal shunts developed in 6 patients(46.1%)at the radial optic neurotomy site.No surgical complications were observed.Conclusions:Radial optic neurotomy seems to be a potential treatment in selected patients with hemicentral retinal vein occlusion,probably because of the more rapid appearance of retinochorioretinal collateral vessels,which promote faster resolution of macular edema.展开更多
文摘PURPOSE: To report three cases of nonarteritic anterior ischemic optic neuropa thy (NAION) that occurred in patients with sleep apnea syndrome (SAS) while bein g treated with continuous positive airway pressure (CPAP). DESI- GN: A prospective, noncomparative case series. METHODS: Prospective review of 108 patients with NAION diagnosed between 2002 and 2003 to identify any patients who developed NAION while being treated for SAS with CPAP. RESULTS: One patient had bilateral sequential NAION and two patients had unilateral NAION despite tr eatment with CPAP for SAS. All the patients were being treated with CPAP for a p eriod ranging from 4 months to 6 years before the onset of NAION. CONCLUSIONS: I n this series, CPAP did not prevent the development of NAION in SAS patients. Larger observational studies are needed to study the benefit of CPAP in preven ting NAION in patients with SAS.
文摘Purpose. To evaluate the effect of intravitreal triamcinolone acetonide on visual acuity in branch retinal vein occlusion. Methods. The prospective comparative nonrandomized clinical interventional study included 28 patients (28 eyes) with branch retinal vein occlusion. The study group consisting of 10 consecutive patients received an intravitreal injection of 20- 25mg of triamcinolone acetonide. The control group including 18 patients did not receive an intravitreal injection. The mean follow-up was 8.7± 4.4 months. Results. In the study group, mean visual acuity increased significantly (P=0.02) from 0.27± 0.11 preoperatively to a best postoperative visual acuity of 0.45± 0.27. Visual acuity measurements determined 1 month after the injection were significantly (P=0.027) higher than baseline values. Nine (90% ) eyes gained in visual acuity, with six (60% ) eyes showing an increase in visual acuity of at least two Snellen lines. In the ischaemic subgroup, visual acuity did not change significantly (0.18± 0.18 to 0.13± 0.04; P=0.66), while, in the nonischaemic subgroup, visual acuity increased significantly (P=0.012) from the baseline value to the best postoperative measurement (0.29± 0.09 to 0.53± 0.24). In the control group, baseline visual acuity and best visual acuity during the follow-up did not vary significantly (P=0.27). Comparing the study and control groups with each other, the gain in visual acuity was significantly higher in the study group at 1 month (P=0.016) and 2 months (P=0.012) after baseline. Conclusions. Intravitreal injection of triamcinolone acetonide can increase visual acuity in patients with branch retinal vein occlusion.
文摘Objective:To evaluate the effect of radial optic neurotomy on visual acuity(VA)and foveal thickness in patients with hemicentral retinal vein occlusion.Methods:A prospective noncomparative case series of 13 eyes in 13 patients with hemicentral retinal vein occlusion and a preoperative VA of 20/60 or less from a total of 232 retinal vein occlusions diagnosed.All patients underwent pars plana vitrectomy,posterior hyaloid dissection,and radial optic neurotomy at the nasal border of the optic disc.Results:Visual acuity and macular thickness were measured with optical coherence tomography.Nine patients(69.2%)gained 2 ormore Snellen lines of vision,and in 4 patients(30.8%)VA improved by 4 ormore Snellen lines(median visual acuity,20/50;mean VA,20/45;P<.01)(average gain,2.7 Snellen lines).The decrease in foveal thickness was statistically significant(P<.01)(median decrease,297 μ m).Final VA was statistically related to decreased macular thickness at optical coherence tomography(P=.03;ρ =-0.62).Retinochoroidal shunts developed in 6 patients(46.1%)at the radial optic neurotomy site.No surgical complications were observed.Conclusions:Radial optic neurotomy seems to be a potential treatment in selected patients with hemicentral retinal vein occlusion,probably because of the more rapid appearance of retinochorioretinal collateral vessels,which promote faster resolution of macular edema.
