Background and study aims: The current visualization of small- bowel strictures using traditional radiological methods is associated with high radiation doses and false- negative results. These methods do not always r...Background and study aims: The current visualization of small- bowel strictures using traditional radiological methods is associated with high radiation doses and false- negative results. These methods do not always reveal small- bowel patency for solids. The aim is to assess the safety of the Given patency system and its ability to detect intestinal strictures in patients with strictures that are known or suspected radiologically. Materials and methods: The Given patency capsule is composed of lactose, remains intact in the gastrointestinal tract for 40- 100 hours post ingestion, and disintegrates thereafter. A total of 34 patients with small- bowel stricture were prospectively enrolled; 30 had a previous diagnosis of Crohn’ s disease, three had adhesion syndrome and in one ischemic enteritis was suspected. Of the patients, 15 (44.1% ) had previously undergone surgery. Following ingestion, the capsule was monitored for integrity and transit time, using a specially designed Given scanner and also radiologically. Seventeen patients had been enrolled with the intent of using the patency capsule as a preliminary test in patients with small- bowel strictures before undergoing video capsule endoscopy. Results: 30 patients (88.2% ) retrieved the capsule in the stool; it was intact in 20 (median transit time 22 hours), and disintegrated in 10 patients (median transit time 53 hours). Six patients complained of abdominal pain which disappeared within 24 hours. The scanner successfully indicated the presence of the capsule in 94% of cases. Ten patients underwent video capsule endoscopy following the patency capsule examination; in all of these the video capsule passed through the small- bowel stricture. Conclusions: This feasibility study has shown that the Given patency capsule is a safe, effective, and convenient tool for assessment of functional patency of the small bowel. It can indicate functional patency even in cases where traditional radiology indicates stricture.展开更多
1974年湖北省新州县人民医院内科用糯稻(Oryza sativa L.) 秆治疗急性黄疸肝炎有效率达86.2%,改善病人食欲尤为显著,且无毒性。作者将糯稻秆用水、乙醇等提取分离,用氨基酸自动分析仪分析,证实含有异亮氨酸、亮氨酸、缬氨酸等12种氨基酸...1974年湖北省新州县人民医院内科用糯稻(Oryza sativa L.) 秆治疗急性黄疸肝炎有效率达86.2%,改善病人食欲尤为显著,且无毒性。作者将糯稻秆用水、乙醇等提取分离,用氨基酸自动分析仪分析,证实含有异亮氨酸、亮氨酸、缬氨酸等12种氨基酸;以聚酰胺层析,证明含有多种酚酸;黄酮结晶经紫外、红外等四大光谱分析证明为5,7,4′-三羟基-3′,5′-二甲氧基黄酮(tricin)。展开更多
文摘Background and study aims: The current visualization of small- bowel strictures using traditional radiological methods is associated with high radiation doses and false- negative results. These methods do not always reveal small- bowel patency for solids. The aim is to assess the safety of the Given patency system and its ability to detect intestinal strictures in patients with strictures that are known or suspected radiologically. Materials and methods: The Given patency capsule is composed of lactose, remains intact in the gastrointestinal tract for 40- 100 hours post ingestion, and disintegrates thereafter. A total of 34 patients with small- bowel stricture were prospectively enrolled; 30 had a previous diagnosis of Crohn’ s disease, three had adhesion syndrome and in one ischemic enteritis was suspected. Of the patients, 15 (44.1% ) had previously undergone surgery. Following ingestion, the capsule was monitored for integrity and transit time, using a specially designed Given scanner and also radiologically. Seventeen patients had been enrolled with the intent of using the patency capsule as a preliminary test in patients with small- bowel strictures before undergoing video capsule endoscopy. Results: 30 patients (88.2% ) retrieved the capsule in the stool; it was intact in 20 (median transit time 22 hours), and disintegrated in 10 patients (median transit time 53 hours). Six patients complained of abdominal pain which disappeared within 24 hours. The scanner successfully indicated the presence of the capsule in 94% of cases. Ten patients underwent video capsule endoscopy following the patency capsule examination; in all of these the video capsule passed through the small- bowel stricture. Conclusions: This feasibility study has shown that the Given patency capsule is a safe, effective, and convenient tool for assessment of functional patency of the small bowel. It can indicate functional patency even in cases where traditional radiology indicates stricture.
文摘1974年湖北省新州县人民医院内科用糯稻(Oryza sativa L.) 秆治疗急性黄疸肝炎有效率达86.2%,改善病人食欲尤为显著,且无毒性。作者将糯稻秆用水、乙醇等提取分离,用氨基酸自动分析仪分析,证实含有异亮氨酸、亮氨酸、缬氨酸等12种氨基酸;以聚酰胺层析,证明含有多种酚酸;黄酮结晶经紫外、红外等四大光谱分析证明为5,7,4′-三羟基-3′,5′-二甲氧基黄酮(tricin)。
