目的探讨白细胞滤器在肿瘤、血液病患者输血治疗中的作用,进一步证实白细胞过滤的临床应用价值。方法回顾肿瘤和血液病患者使用滤白机采血小板的情况,并通过发热性非溶血性输血反应(FNHTR)率、血小板有效输注及24 h校正血小板计数增加值...目的探讨白细胞滤器在肿瘤、血液病患者输血治疗中的作用,进一步证实白细胞过滤的临床应用价值。方法回顾肿瘤和血液病患者使用滤白机采血小板的情况,并通过发热性非溶血性输血反应(FNHTR)率、血小板有效输注及24 h校正血小板计数增加值(CCI)与未进行白细胞滤除的机采血小板输注相比较。结果过滤机采血小板组和未过滤机采血小板组发热性非溶血性输血反应发生率差异有显著性(P<0.05);过滤机采血小板组和未过滤机采血小板组的血小板输注有效率差异无显著性(P>0.05),24 h CCI值差异无显著性(P>0.05)。结论白细胞滤器能有效地减少机采血小板的发热性非溶血性输血反应,且不影响输注效果。展开更多
Objective: To assess the clinical efficiency of the transfusion of leucocyte filtrated RBC concentrates to prevent febrile nonhemolytic transfusion reactions (FNHTRs). Methods: One hundred patients with liver cirrhosi...Objective: To assess the clinical efficiency of the transfusion of leucocyte filtrated RBC concentrates to prevent febrile nonhemolytic transfusion reactions (FNHTRs). Methods: One hundred patients with liver cirrhosis, gastric ulcer or cancer were subjected to receive RBC concentrates after leucocyte filtration. Another 50 patients with similar diseases were selected to receive non-filtrated RBC concentrates. The incidence of FNHTRs in all patients was investigated. Results: There was no FNHTR in 100 transfusions with leucocyte filtrated RBC concentrates, while FNHTRs occurred in 8 of 50 patients with non-filtrated RBC concentrates, with the incidence of 16%. Conclusion: FNHTRs to RBC transfusion can be prevented with leucocyte filtration.展开更多
文摘目的探讨白细胞滤器在肿瘤、血液病患者输血治疗中的作用,进一步证实白细胞过滤的临床应用价值。方法回顾肿瘤和血液病患者使用滤白机采血小板的情况,并通过发热性非溶血性输血反应(FNHTR)率、血小板有效输注及24 h校正血小板计数增加值(CCI)与未进行白细胞滤除的机采血小板输注相比较。结果过滤机采血小板组和未过滤机采血小板组发热性非溶血性输血反应发生率差异有显著性(P<0.05);过滤机采血小板组和未过滤机采血小板组的血小板输注有效率差异无显著性(P>0.05),24 h CCI值差异无显著性(P>0.05)。结论白细胞滤器能有效地减少机采血小板的发热性非溶血性输血反应,且不影响输注效果。
文摘Objective: To assess the clinical efficiency of the transfusion of leucocyte filtrated RBC concentrates to prevent febrile nonhemolytic transfusion reactions (FNHTRs). Methods: One hundred patients with liver cirrhosis, gastric ulcer or cancer were subjected to receive RBC concentrates after leucocyte filtration. Another 50 patients with similar diseases were selected to receive non-filtrated RBC concentrates. The incidence of FNHTRs in all patients was investigated. Results: There was no FNHTR in 100 transfusions with leucocyte filtrated RBC concentrates, while FNHTRs occurred in 8 of 50 patients with non-filtrated RBC concentrates, with the incidence of 16%. Conclusion: FNHTRs to RBC transfusion can be prevented with leucocyte filtration.
