Background.To report a case of succe ssful management of a FIGO stage III endometrioid carcin oma of the ovary di-agnosed during pregnancy at 22weeks of gestation and treated with initial chemotherapy w hile preservin...Background.To report a case of succe ssful management of a FIGO stage III endometrioid carcin oma of the ovary di-agnosed during pregnancy at 22weeks of gestation and treated with initial chemotherapy w hile preserving the pregnancy.Case.The patient underw ent a planned ce-sarean section at 34weeks after two c ourses of carboplatin.She delivered a healthy baby.At the s ame time,a radical hysterectomy,omentectomy,pelvic and paraaortic lym-phadenectomies and peritonectomie s were carried out.The surgical resection was complete(no macroscopic residual disease).During histologic examination,tr aces of persis-tent disease were found.The patient underwent seven postoperative courses of chemotherapy(carboplatin +pa-clitaxel regimen)after radical surgery.After 18mont hs of follow-up posttreatment,the patie nt remains in complete remission and the childs developme nt is normal.Conclu-sion.Chemotherapy during pregnancywith preservation of the fetus could be considered and should be discussed in case of epithelial ovarian cancer(EOC)diagnosed during the second trimester of the pregnancy.展开更多
文摘Background.To report a case of succe ssful management of a FIGO stage III endometrioid carcin oma of the ovary di-agnosed during pregnancy at 22weeks of gestation and treated with initial chemotherapy w hile preserving the pregnancy.Case.The patient underw ent a planned ce-sarean section at 34weeks after two c ourses of carboplatin.She delivered a healthy baby.At the s ame time,a radical hysterectomy,omentectomy,pelvic and paraaortic lym-phadenectomies and peritonectomie s were carried out.The surgical resection was complete(no macroscopic residual disease).During histologic examination,tr aces of persis-tent disease were found.The patient underwent seven postoperative courses of chemotherapy(carboplatin +pa-clitaxel regimen)after radical surgery.After 18mont hs of follow-up posttreatment,the patie nt remains in complete remission and the childs developme nt is normal.Conclu-sion.Chemotherapy during pregnancywith preservation of the fetus could be considered and should be discussed in case of epithelial ovarian cancer(EOC)diagnosed during the second trimester of the pregnancy.
