在小鼠柯萨奇B_3 病毒性心肌炎模型上采用卡托普利治疗其感染时和感染1周后的疗效,并与维生素 C 治疗组和生理盐水对照组比较。结果:卡托普利对其感染时的生存率高于对照组(P<0.005)和维生素 C 组(P<0.05),感染1周后用药生存率高...在小鼠柯萨奇B_3 病毒性心肌炎模型上采用卡托普利治疗其感染时和感染1周后的疗效,并与维生素 C 治疗组和生理盐水对照组比较。结果:卡托普利对其感染时的生存率高于对照组(P<0.005)和维生素 C 组(P<0.05),感染1周后用药生存率高于对照组(P<0.01),心肌炎症、坏死、钙化的程度在感染同时或1周后用药均明显低于对照组(P<0.001)和维生素 C 组(P<0.005),心脏重量均低于对照组;而难生素 C 治疗组心肌炎症、坏死、钙化的程度在感染时用药轻于对照组(P<0.005)。表明卡托普利对病毒性心肌炎有良好作用,且疗效较维生素 C 优。展开更多
Objective: To investigate the protective effectof Qidongyixin Oral Liquidon cultured rat cardiomyocytes infected withCVB 3 . Methods:Monolayer culture of spontaneously contracting rat heart cells were obtained from ne...Objective: To investigate the protective effectof Qidongyixin Oral Liquidon cultured rat cardiomyocytes infected withCVB 3 . Methods:Monolayer culture of spontaneously contracting rat heart cells were obtained from new born SD rats and seeded into culture plates. Results:Chronic Pulmonary Emphysema was lightened,Qidongyixin Oral Liquidcould inhibit the release of cardiac cytosolic enzymes-lactic acid dehydrogenase and glutamic-pyruvic transaminase. Conclusion: Qidongyixin Oral Liquidhas protective effects on viral myocarditis.展开更多
文摘在小鼠柯萨奇B_3 病毒性心肌炎模型上采用卡托普利治疗其感染时和感染1周后的疗效,并与维生素 C 治疗组和生理盐水对照组比较。结果:卡托普利对其感染时的生存率高于对照组(P<0.005)和维生素 C 组(P<0.05),感染1周后用药生存率高于对照组(P<0.01),心肌炎症、坏死、钙化的程度在感染同时或1周后用药均明显低于对照组(P<0.001)和维生素 C 组(P<0.005),心脏重量均低于对照组;而难生素 C 治疗组心肌炎症、坏死、钙化的程度在感染时用药轻于对照组(P<0.005)。表明卡托普利对病毒性心肌炎有良好作用,且疗效较维生素 C 优。
文摘Objective: To investigate the protective effectof Qidongyixin Oral Liquidon cultured rat cardiomyocytes infected withCVB 3 . Methods:Monolayer culture of spontaneously contracting rat heart cells were obtained from new born SD rats and seeded into culture plates. Results:Chronic Pulmonary Emphysema was lightened,Qidongyixin Oral Liquidcould inhibit the release of cardiac cytosolic enzymes-lactic acid dehydrogenase and glutamic-pyruvic transaminase. Conclusion: Qidongyixin Oral Liquidhas protective effects on viral myocarditis.
