【目的】回顾性研究母亲产前因素对胎儿生长发育的影响。【方法】统计2003年1月～2004年10月在重庆医科大学附属第一医院产科分娩的孕妇和活产新生儿2250对，分析母亲年龄、身高、体重、文化、职业、孕期疾病、遗传病、胎次、胎龄与胎...【目的】回顾性研究母亲产前因素对胎儿生长发育的影响。【方法】统计2003年1月～2004年10月在重庆医科大学附属第一医院产科分娩的孕妇和活产新生儿2250对，分析母亲年龄、身高、体重、文化、职业、孕期疾病、遗传病、胎次、胎龄与胎儿生长发育的关系。【结果】①2250例活产新生儿中，103例是小于胎龄儿（small for gestational age，SGA）（4．6％）；②宫内生长发育与母亲的年龄分布、文化程度、妊娠并发症如妊高征、心脏病、胆淤症等因素有关（P〈0．05），与母亲身高、孕期、胎次无关（P〉0．05）。【结论】①母亲生育的年龄影响胎儿生长发育，母亲24岁以前生育发生SGA的机会增加；②母亲妊娠期疾病影响胎儿生长发育，母身高、孕期和胎次与胎儿出生身长无相关性。Ⅲ¨㈨LI-．1………●．…展开更多
Objective: To identify prenatal risk factors for chronic lung disease (CLD) at 36 weeks postmenstrual age in very preterm infants. Population: Data were colle cted prospectively as part of the ongoing audit of the Aus...Objective: To identify prenatal risk factors for chronic lung disease (CLD) at 36 weeks postmenstrual age in very preterm infants. Population: Data were colle cted prospectively as part of the ongoing audit of the Australian and New Zealan d Neonatal Network (ANZNN) of all infants born at less than 32 weeks gestation a dmitted to all tertiary neonatal intensive care units in Australia and New Zeala nd. Methods: Prenatal factors up to 1 minute of age were examined in the subset of infants born at gestational ages 22-31 weeks during 1998-2001, and who surv ived to 36 weeks postmenstrual age (n=11 453). Factors that were significantly associated with CLD at 36 weeks were entered into a multivariate logistic regress ion model. Results: After adjustment, low gestational age was the dominant risk factor, with an approximate doubling of the odds with each week of decreasing ge stational age from 31 to less than 25 weeks (trend P < 0.0001). Birth weight for gestational age also had a dose-response effect: the lower the birth weight for gestational age, the greater the risk, with infants below the third centile having 5.67 times greater odds of CLD than those between the 25th and 75th centile (trend P < 0.0001). There was also a significantly increased risk for male infa nts (odds ratio 1.51 (95%confidence interval 1.36 to 1.68), P < 0.0001). Conclu sions: These population based data show that the prenatal factors low gestational age, low birth weight for gestational age, and male sex significantly predict the development of chronic respiratory insufficiency in very preterm infants and may assist clinical decision about delivery.展开更多
一些产前因素可能会影响孩子的血压,但是目前还没有确凿的证据,且其中的机制尚未明确。研究者检查儿童期收缩压与胎儿子宫内生长期间的5项潜在、可改变的产前因素以及儿童期生长状况之间的相关性，这5项产前因素分别是母亲妊娠期吸烟、...一些产前因素可能会影响孩子的血压,但是目前还没有确凿的证据,且其中的机制尚未明确。研究者检查儿童期收缩压与胎儿子宫内生长期间的5项潜在、可改变的产前因素以及儿童期生长状况之间的相关性，这5项产前因素分别是母亲妊娠期吸烟、孕前体质量指数（body mass index，BMI）、展开更多
文摘【目的】回顾性研究母亲产前因素对胎儿生长发育的影响。【方法】统计2003年1月～2004年10月在重庆医科大学附属第一医院产科分娩的孕妇和活产新生儿2250对，分析母亲年龄、身高、体重、文化、职业、孕期疾病、遗传病、胎次、胎龄与胎儿生长发育的关系。【结果】①2250例活产新生儿中，103例是小于胎龄儿（small for gestational age，SGA）（4．6％）；②宫内生长发育与母亲的年龄分布、文化程度、妊娠并发症如妊高征、心脏病、胆淤症等因素有关（P〈0．05），与母亲身高、孕期、胎次无关（P〉0．05）。【结论】①母亲生育的年龄影响胎儿生长发育，母亲24岁以前生育发生SGA的机会增加；②母亲妊娠期疾病影响胎儿生长发育，母身高、孕期和胎次与胎儿出生身长无相关性。Ⅲ¨㈨LI-．1………●．…
文摘Objective: To identify prenatal risk factors for chronic lung disease (CLD) at 36 weeks postmenstrual age in very preterm infants. Population: Data were colle cted prospectively as part of the ongoing audit of the Australian and New Zealan d Neonatal Network (ANZNN) of all infants born at less than 32 weeks gestation a dmitted to all tertiary neonatal intensive care units in Australia and New Zeala nd. Methods: Prenatal factors up to 1 minute of age were examined in the subset of infants born at gestational ages 22-31 weeks during 1998-2001, and who surv ived to 36 weeks postmenstrual age (n=11 453). Factors that were significantly associated with CLD at 36 weeks were entered into a multivariate logistic regress ion model. Results: After adjustment, low gestational age was the dominant risk factor, with an approximate doubling of the odds with each week of decreasing ge stational age from 31 to less than 25 weeks (trend P < 0.0001). Birth weight for gestational age also had a dose-response effect: the lower the birth weight for gestational age, the greater the risk, with infants below the third centile having 5.67 times greater odds of CLD than those between the 25th and 75th centile (trend P < 0.0001). There was also a significantly increased risk for male infa nts (odds ratio 1.51 (95%confidence interval 1.36 to 1.68), P < 0.0001). Conclu sions: These population based data show that the prenatal factors low gestational age, low birth weight for gestational age, and male sex significantly predict the development of chronic respiratory insufficiency in very preterm infants and may assist clinical decision about delivery.
