This article presents a brief overview of the development of high-resolution SPECT for small-animal im- aging. A pinhole collimator has been used for high-resolution animal SPECT to provide better spatial resolution a...This article presents a brief overview of the development of high-resolution SPECT for small-animal im- aging. A pinhole collimator has been used for high-resolution animal SPECT to provide better spatial resolution and detection efficiency in comparison with a parallel-hole collimator. The theory of imaging characteristics of the pin- hole collimator is presented and the designs of the pinhole aperture are discussed. The detector technologies used for the development of small-animal SPECT and the recent advances are presented. The evolving trend of small-animal SPECT is toward a multi-pinhole and a multi-detector system to obtain a high resolution and also a high detection ef- ficiency.展开更多
A set of point spread functions (PSF) has been obtained by means of Monte-Carlo simulation for asmall gamma camera with a pinhole collimator of various hole diameters. The FOV (field of view) of the camera isexpended ...A set of point spread functions (PSF) has been obtained by means of Monte-Carlo simulation for asmall gamma camera with a pinhole collimator of various hole diameters. The FOV (field of view) of the camera isexpended from 45 mm to 70 mm in diameter. The position dependence of the variances of PSF is presented, and theacceptance for the 140 kev gamma rays is explored. A phantom of 70 mm in diameter was experimentally imaged inthe camera with effective FOV of only 45 mm in diameter.展开更多
A new compact gamma camera for small object imaging has been developed.It consists of a pixelized Nal(T1) scintillator array coupled to a position sensitive photomultiplier tube (Hamamatsu R2486) with a parallel-hole ...A new compact gamma camera for small object imaging has been developed.It consists of a pixelized Nal(T1) scintillator array coupled to a position sensitive photomultiplier tube (Hamamatsu R2486) with a parallel-hole lead collimator.The compact camera has better spatial resolution than Anger camera.The average value of intrinsic spatial resolutions is 2.3 mm (FWHM).The overall spatial resolution (FWHM) is 3,5 and 6 mm at 0,2.5 and 3 mm SCD (source-to-collimator distance),respectively.The phantom studies with the compact camera have demonstrated that parallel-hole collimator gamma camera is a practical technique for nuclear medicine application.展开更多
文摘This article presents a brief overview of the development of high-resolution SPECT for small-animal im- aging. A pinhole collimator has been used for high-resolution animal SPECT to provide better spatial resolution and detection efficiency in comparison with a parallel-hole collimator. The theory of imaging characteristics of the pin- hole collimator is presented and the designs of the pinhole aperture are discussed. The detector technologies used for the development of small-animal SPECT and the recent advances are presented. The evolving trend of small-animal SPECT is toward a multi-pinhole and a multi-detector system to obtain a high resolution and also a high detection ef- ficiency.
基金Supported by the National Natural Science Foundation of China(10275063)
文摘A set of point spread functions (PSF) has been obtained by means of Monte-Carlo simulation for asmall gamma camera with a pinhole collimator of various hole diameters. The FOV (field of view) of the camera isexpended from 45 mm to 70 mm in diameter. The position dependence of the variances of PSF is presented, and theacceptance for the 140 kev gamma rays is explored. A phantom of 70 mm in diameter was experimentally imaged inthe camera with effective FOV of only 45 mm in diameter.
基金Supported by National Natural Science Foundation of China (No.10275063)
文摘A new compact gamma camera for small object imaging has been developed.It consists of a pixelized Nal(T1) scintillator array coupled to a position sensitive photomultiplier tube (Hamamatsu R2486) with a parallel-hole lead collimator.The compact camera has better spatial resolution than Anger camera.The average value of intrinsic spatial resolutions is 2.3 mm (FWHM).The overall spatial resolution (FWHM) is 3,5 and 6 mm at 0,2.5 and 3 mm SCD (source-to-collimator distance),respectively.The phantom studies with the compact camera have demonstrated that parallel-hole collimator gamma camera is a practical technique for nuclear medicine application.
